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Methods for the prevention or treatment of no-reflow following ischemia/reperfusion injury

  • US 9,345,738 B2
  • Filed: 07/08/2011
  • Issued: 05/24/2016
  • Est. Priority Date: 07/09/2010
  • Status: Active Grant
First Claim
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1. A method for treating a anatomic zone of no re-flow in a mammalian subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a peptide D-Arg-2′

  • ,6′

    -Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof, thereby treating the anatomical zone of no re-flow in the subject, wherein the anatomic zone of no re-flow comprises a zone of persistent ischemia.

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