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Liquid levothyroxine formulations

  • US 9,345,772 B1
  • Filed: 02/27/2015
  • Issued: 05/24/2016
  • Est. Priority Date: 02/27/2015
  • Status: Active Grant
First Claim
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1. A pharmaceutical solution comprising:

  • from 0.001% w/v to 0.01% w/v of a levothyroxine;

    from 75% w/w to 95% of glycerol;

    from 0.01% w/w to 1.5% w/w of an ethylenediaminetetraacetic acid (EDTA); and

    an amount of water sufficient to adjust the pharmaceutical solution to 100% w/w, andwherein the solution is storage stable.

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