Luminescent nanostructured materials for use in electrogenerated chemiluminescence

• US 9,346,997 B2
• Filed: 07/09/2014
• Issued: 05/24/2016
• Est. Priority Date: 05/08/2008
• Status: Active Grant

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Bard, Allen J., Fan, Fu-Ren F., Omer, Khalid
• Primary Examiner(s): Xu, Robert
• Application Number:
  US14/327,326
• Publication Number:
  US 20140322538A1
• Time in Patent Office: 685 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: B82Y 20/00 Nanooptics, e.g. quantum optics or photonic crystals
• CPC Class Codes: C07C 2/64 Addition to a carbon atom of a six-membered aromatic ring
• CPC Class Codes: C09K 11/06 containing organic luminescent materials
• CPC Class Codes: C09K 11/07 having chemically interreactive components, e.g. reactive chemiluminescent compositions
• CPC Class Codes: C09K 2211/1007 Non-condensed systems
• CPC Class Codes: C09K 2211/1011 Condensed systems
• CPC Class Codes: G01N 21/64 Fluorescence; Phosphorescence
• CPC Class Codes: G01N 21/66 electrically excited, e.g. electroluminescence
• CPC Class Codes: G01N 21/76 Chemiluminescence; Bioluminescence
• CPC Class Codes: Y10T 428/298 Physical dimension
• CPC Class Codes: Y10T 428/2982 Particulate matter [e.g., sphere, flake, etc.]

Abstract

A nanostructured particulates formed from a redox active, luminescent phenyl substituted polycyclic aromatic hydrocarbon are provided herein. The nanostructured particulates may be used for determining the presence of an analyte of interest in a sample by detecting the emitted electromagnetic radiation generated by exposing a reagent mixture, which includes the nanostructured particulates and the sample, to electrochemical energy.

Claims

1. 9,10-Diphenvlanthracene nanorods;

wherein the nanorods have a least two dimensions which are no larger than about 200 nm.

2. The nanorods of claim 1, wherein the nanorods are substantially free of surfactant.

3. The nanorods of claim 1, wherein the nanorods can be induced to repeatedly emit electromagnetic radiation by direct exposure to an electrochemical energy source.

4. The nanorods of claim 1, wherein the nanorods have an average hydrodynamic radius of no more than about 100 nm.

5. The nanorods of claim 1, wherein the 9,10-diphenylanthracene nanorods have a diameter of about 10 to 150 nm and a length of about 50 nm to 1 micron.

6. The nanorods of claim 1, wherein the nanorods are polydisperse 9,10-diphenylanthracene nanorods with diameters of about 20 to 100 nm and lengths of about 100 to 600 nm.

7. The nanorods of claim 1, wherein the 9,10-diphenylanthracene nanorods have an average hydrodynamic radius of about 45 nm.

10. The nanorods of claim 1, wherein the nanorods are formed by a process which comprises injecting a solution of 9,10-diphenylanthracene in organic solvent into deionized water.

11. The nanorods of claim 1 comprising polydisperse nanorods consisting essentially of 9,10-diphenylanthracene, wherein the nanorods have an average diameter of about 10 to 150 nm and an average length of about 50 nm to 1 micron.

12. The nanorods of claim 11, wherein the polydisperse nanorods are substantially free of surfactant.

8. Nanorods having a least two dimensions which are no larger than about 200 nm wherein nanorods are formed by a process which comprises injecting a 9,10-diphenylanthracene solution in organic solvent into deionized water;

wherein the organic solvent is acetonitrile, tetrahydrofuran, and/or N,N-dimethylformamide.

9. The nanorods of claim 8, wherein the organic solvent is acetonitrile.

13. The nanorods of claim 8, wherein the nanorods are polydisperse nanorods consisting essentially of 9,10-diphenylanthracene, wherein the nanorods have an average diameter of about 10 to 150 nm and an average length of about 50 nm to 1 micron.

14. The nanorods of claim 8, wherein the nanorods have an average hydrodynamic radius of no more than about 100 nm.

15. The nanorods of claim 8, wherein the nanorods have an average hydrodynamic radius of about 45 nm.

16. The nanorods of claim 8, wherein the nanorods are polydisperse 9,10-diphenylanthracene nanorods with diameters of about 20 to 100 nm and lengths of about 100 to 600 nm.

17. The nanorods of claim 8, wherein the nanorods are substantially free of surfactant.