Device and method for sensing electrical activity in tissue

• US 9,351,658 B2
• Filed: 08/08/2006
• Issued: 05/31/2016
• Est. Priority Date: 09/02/2005
• Status: Active Grant

• Current Assignee: Nielsen Consumer LLC (Nielsen Holdings plc)
• Original Assignee: The Nielsen Company LLC (MOOD Media Corporation)
• Inventors: Lee, Michael J., Lee, Hans C.
• Primary Examiner(s): EISEMAN, ADAM JARED
• Application Number:
  US11/500,678
• Publication Number:
  US 20070055169A1
• Time in Patent Office: 3,584 Days
• Field of Search: 600/544, 600/545, 600/546, 128/925
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0015 characterised by features of the telemetry system
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/374 Detecting the frequency distribution of signals, e.g. detecting delta, theta, alpha, beta or gamma waves
• CPC Class Codes: A61B 5/6803 Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 5/6814 Head
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

An exemplary embodiment providing one or more improvements includes apparatus and methods for sensing electrical activity in tissue of a person in a manner which is substantially limits or eliminates interference from noise in a surrounding environment.

Claims

1. A method comprising:

detecting electrical activity from a tissue of a user via a sensor of a headpiece worn by the user, the sensor including;

a sensor electrode to contact a first point on skin of the user;

a reference electrode to contact a second point on the skin of the user, the contact between the reference electrode and the skin of the user to cause a contact resistance between a surface of the reference electrode and the skin of the user; and

an electronics module positioned proximate the reference electrode to reduce noise, a local reference potential in the electronics module and a potential of the second point on the skin being approximately equal to allow the surface of the reference electrode to be in direct contact with the skin of the user at the second point without having to prepare the skin or use a material that decreases the contact resistance, the electrical activity represented by a voltage signal including a signal of interest, undesired signals, and noise, the electronics module including;

an amplifier to (1) amplify the signal of interest and the undesired signals within a first frequency range while (2) filtering the noise occurring in a second frequency range, which includes frequencies higher than the first frequency range, prior to transmitting the amplified signal of interest and undesired signals to one or more filters; and

transforming, with a processor and a Fourier transform, the signal of interest to form an output signal.

2. A method as defined in claim 1, wherein the amplifier is to amplify the signal of interest and the undesired signals by using the local reference potential of the electronics module, and connecting the second point directly to the local reference potential.

3. A method as defined in claim 1, wherein the amplifier is to amplify the signal of interest at the electronics module by using the local reference potential and source voltages, and positioning the electronics module in a region of the headpiece adjacent to the second point so as to electrically couple the local reference potential and source voltages to the second point.

4. A method as defined in claim 1, wherein the amplifier is to amplify the signal of interest at the electronics module and detecting the electrical activity includes using conductors extending from the electronics module to the sensor and reference electrodes at the first and second points, and electrically isolating the electronics module by keeping the electronics module free of wires, optical fibers or other extensions other than the conductors extending to the sensor and reference electrodes.

5. A method as defined in claim 1 further including filtering an output signal of the amplifier with the electronics module to attenuate the undesired signals and to isolate the signal of interest from the undesired signals.

6. A method as defined in claim 5 further including communicating the signal of interest to a computing device.

7. A method as defined in claim 6, wherein the computing device is to display information relating to the signal of interest.

8. A method as defined in claim 6, wherein the computing device is to produce audio related to the signal of interest.

9. A method as defined in claim 5, wherein the signal of interest relates to electrical activity in brain tissue of the user.

10. A method as defined in claim 5, wherein the signal of interest relates to electrical activity in muscle tissue of the user.

11. A method as defined in claim 5, wherein the signal of interest relates to electrical activity in heart tissue of the user.

12. A method as defined in claim 5, wherein filtering the output signal of the amplifier attenuates undesired signals below about 4 Hz and above about 12 Hz.

13. A method as defined in claim 5, wherein the signal of interest includes Alpha and Theta band brain waves.

14. A method as defined in claim 1, wherein the second point is on an ear of the user.

15. A method as defined in claim 1, wherein the second point is approximately 4 inches from the first point.

16. A method as defined in claim 1, wherein the second point is on a forehead of the user.

17. A method as defined in claim 1, wherein the second point is within approximately 8 inches of the first point.

18. A method as defined in claim 1, wherein the undesired signals include noise signals caused by environmental noise.

19. A method as defined in claim 1, wherein a contact resistance of the sensor electrode and the reference electrode can be as high as 500,000 ohms.

20. A method as defined in claim 1 further including positioning the electronics module with the processor at a temple of the user and positioning the reference electrode at an ear of the user.

21. A method as defined in claim 20, wherein the processor and reference electrode are to be positioned at the right temple and ear of the user.

22. A method as defined in claim 1 further including:

isolating the signal of interest from the undesired signals by filtering the output signal.

23. A method as defined in claim 1, wherein the processor is to convert the output signal from analog to digital, wherein the output signal is converted at a rate that is a multiple of 60 Hz.

24. A method as defined in claim 1 further including testing the output signal for data that is inconsistent with EEG data, and removing the inconsistent data from the output signal.

25. A method as defined in claim 1 further including transforming the output signal using the Fourier Transform to determine an energy spectrum signal based on an energy spectrum of the output signal.

26. A method as defined in claim 25 further including dividing the energy spectrum signal into groups of 60 samples and separating the energy spectrum into 1 Hz wide bins.

27. A method as defined in claim 25 further including dividing the energy spectrum signal into groups of 30 samples and separating the energy spectrum into 2 Hz wide bins.

28. A method as defined in claim 25 further including dividing the energy spectrum signal into groups of samples and separating the energy spectrum into bins which each represent energy in a certain range of frequencies, and summing energy in bins that have about 4-8 Hz to create a Theta band energy signal.

29. A method as defined in claim 28 further including summing energy in bins that have about 8-12 Hz to create an Alpha band energy signal.

30. A method as defined in claim 29 further including generating the signal of interest by determining a ratio of the Alpha and Theta band energy signals.

32. A method as defined in claim 1 further including:

sampling the output signal for a certain number of samples in each 1/60^th of a second; and

summing the samples from each 1/60^th of a second to create a processed signal with no 60 Hz interference.

33. A method as defined in claim 1, wherein the sensor electrode is electrically coupled to a first input of the amplifier, the reference electrode is electrically coupled to a second input of the amplifier, and an output of the amplifier is electrically coupled to the second input of the amplifier via a low pass filter.

34. A method as defined in claim 33, wherein the reference electrode is in circuit with the local reference potential in the electronics module.

35. A method as defined in claim 34, wherein a signal path of the sensor electrode to the first input is electrically isolated from a signal path of the reference electrode to the second input.

36. A method as defined in claim 1, wherein the amplifier is a low pass operational amplifier.

37. A method as defined in claim 36, wherein the noise includes signals above about 60 Hz.

38. A method as defined in claim 1, wherein the electronics module further includes a filter electrically coupled to an output of the amplifier, wherein the filter is to isolate the signal of interest and further attenuate the noise.

39. A method as defined in claim 38, wherein the amplifier is a first amplifier, and the filter includes a second amplifier, and wherein the output of the first amplifier is electrically coupled to a first input of the second amplifier, and an output of the second filter is electrically coupled to a second input of the second filter via a low pass filter.

40. A method as defined in claim 1, wherein the electronics module includes a converter to convert the signal of interest into digital form prior to transforming the signal of interest with the Fourier transform.

41. A method as defined in claim 1, wherein the electrical activity is from a muscle and a heart of the user.

31. A method comprising:

detecting electrical activity from a tissue of a user via a sensor of a headpiece worn by the user, the sensor including an electronics module, a sensor electrode and a reference electrode, the sensor electrode is to contact a first point on skin of the user and the reference electrode is to contact a second point on the skin of the user, the contact between the reference electrode and the skin of the user to cause a contact resistance between a surface of the reference electrode and the skin of the user, the electronics module being positioned proximate the reference electrode to reduce noise, a local reference potential in the electronics module and a potential of the second point on the skin being approximately equal to allow the surface of the reference electrode to be in direct contact with the skin of the user at the second point without having to prepare the skin or use a material that decreases the contact resistance, the electrical activity represented by a voltage signal including a signal of interest and undesired signals;

transforming, with a processor, the voltage signal using a Fourier Transform to determine an energy spectrum signal based on an energy spectrum of the voltage signal;

dividing the energy spectrum signal into groups of samples and separating the energy spectrum into bins that represent energy in a certain range of frequencies;

summing energy in bins that have about 4-8 Hz to create a Theta band energy signal;

summing energy in bins that have about 8-12 Hz to create an Alpha band energy signal; and

generating the signal of interest by determining a ratio of the Alpha and Theta band energy signals, wherein the ratio includes (Theta signal−

Alpha signal)/(Theta signal+Alpha signal).