Low frequency neurostimulator for the treatment of neurological disorders

• US 9,352,168 B2
• Filed: 04/16/2015
• Issued: 05/31/2016
• Est. Priority Date: 08/31/2000
• Status: Expired due to Term

• Current Assignee: Neuropace Inc.
• Original Assignee: Neuropace Inc.
• Inventors: Fischell, David R., Upton, Adrian R. M.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US14/688,935
• Publication Number:
  US 20150217127A1
• Time in Patent Office: 411 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61N 1/32 alternating or intermittent currents applying electric fields by inductive or capacitive coupling A61N1/40; microwave apparatus A61N5/02
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 2/006 for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/008 for pain treatment or analgesia
• CPC Class Codes: A61N 2/02 using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence

Abstract

A system for treating neurological conditions by low-frequency time varying electrical stimulation includes an electrical device for applying such low-frequency energy, in a range below approximately 10 Hz, to the patient'"'"'s brain tissue. An implantable embodiment applies direct electrical stimulation to electrodes implanted in or on the patient'"'"'s brain, while a non-invasive embodiment causes a magnetic field to induce electrical currents in the patient'"'"'s brain.

Claims

1. A magnetic depolarizer adapted to be portable and placed on the head of a patient comprising:

at least one magnetic coil;

a power source; and

control circuitry in operable communication with the power source and the at least one magnetic coil, the control circuitry configured to cause the at least one magnetic coil to deliver a single magnetic pulse to the patient as a form of treatment for a neurological disorder when a power is supplied to the control circuitry from the power source,

wherein the single magnetic pulse corresponds to one of a plurality of magnetic pulses provided by a carrier frequency having a low frequency signal modulated thereon.

2. The magnetic depolarizer system of claim 1 wherein the control circuitry is further configured to preset the duration of the single magnetic pulse.

3. The magnetic depolarizer of claim 1 wherein the control circuitry is further configured to preset the duration of the single magnetic pulse to a duration in the range between about 10 microseconds and 1,000 microseconds.

4. The magnetic depolarizer of claim 1 wherein the magnetic field produced by the single magnetic pulse has an intensity of 0.1 to 10 Tesla at a surface of the patient'"'"'s brain.

5. The magnetic depolarizer of claim 1 wherein the power source comprises a rechargeable battery.

6. The magnetic depolarizer of claim 1, wherein the carrier frequency is on the order of 100 Hz.

7. The magnetic depolarizer of claim 1, further comprising a positioning element in which the at least one magnetic coil and the control circuitry may be disposed and configured to be situated on or adjacent the head of the patient.