Continuous, non-invasive, optical blood pressure monitoring system

• US 9,357,933 B2
• Filed: 01/18/2011
• Issued: 06/07/2016
• Est. Priority Date: 01/19/2010
• Status: Active Grant

• Current Assignee: Donna Baldwin, Matthew James Baldwin
• Original Assignee: Donna Baldwin, Matthew James Baldwin
• Inventors: Baldwin, Donna, Baldwin, Matthew James
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): CATINA, MICHAEL ANTHONY
• Application Number:
  US13/008,671
• Publication Number:
  US 20110178415A1
• Time in Patent Office: 1,967 Days
• Field of Search: 600/310, 600/480, 600/485, 356/457, 356/458
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence

Abstract

Various embodiments of the invention disclosed herein comprise a system of wearable devices that collectively allow for the continuous, non-invasive, measurement and monitoring of blood pressure, without the use of an inflatable cuff. The system incorporates: 1) An optical module, which is comprised of a coherent source of light, a semi-transparent hologram, optics for viewing the interference pattern developed between the illuminated hologram and arterial blood, a Charge-Coupled Device (CCD) array, and processing electronics with Bluetooth capability that facilitates digitization and wireless transmission of the fringe pattern to, 2) a personal digital assistant (PDA) that is worn on a waist belt. The PDA and associated software allow for continuous calculation and monitoring of real-time arterial blood pressure from the digitized fringe patterns received. The system further comprises 3) a personal computer (PC) with wireless capacity and connection to the internet. Continuous BP function, alerts, condition and medical assessment is conducted through PDA-PC communications with internet based medical facility.

Claims

1. A device for the non-invasive measurement of a person'"'"'s blood pressure parameters comprising:

a first optical module comprising an optical source of coherent light configured to provide light to a second optical module, said first optical module included in a wearable system configured to be worn on the person;

the second optical module included in the wearable system, the second optical module comprising optics configured to be worn proximal to the person'"'"'s skin, to deliver said coherent light to a sub-dermal region of the person, and to receive light reflected from said sub-dermal region;

an optical connection configured to couple light between the first optical module and the second optical module;

a hologram recorded in a non-transitory medium, said hologram not obtained directly from said person, said hologram configured to provide time dependent interferometric optical information from optical interference using said coherent light reflected from said sub-dermal region;

an electronic imaging system configured to transform the time dependent interferometric optical information into a digital format; and

a processing module configured to receive the time dependent interferometric optical information in a digital format and to calculate blood pressure parameters therefrom.

2. The device of claim 1, wherein said hologram comprises a reference calibration hologram.

3. The device of claim 2, wherein said reference calibration hologram is obtained from a master hologram.

4. The device of claim 2, wherein said reference calibration hologram comprises a holographic image of a fluid that is not blood.

5. The device of claim 1, further comprising a reference arm configured such that said light reflected from said sub-dermal region interferes with light in said reference arm to form interference fringes that are imaged by said electronic imaging system.

6. The device of claim 5, wherein said hologram is disposed in said reference arm.

7. The device of claim 5, further comprising a beamsplitter disposed in an optical path between said optical source of coherent light and said sub-dermal region, said beamsplitter configured to separate light from said optical source into an object beam and a reference beam, said object beam being delivered to said sub-dermal region and said reference beam to said reference arm.

8. The device of claim 7, wherein said hologram is in said reference arm.

9. The device of claim 1, wherein said processing module is included in said wearable system.

10. The device of claim 1, further comprising electronics configured for wireless transmission.

11. The device of claim 10, wherein said electronics configured for wireless transmission is configured to communicate wirelessly with another component worn by said patient.

12. The device of claim 10, wherein said electronics configured for wireless transmission is configured to communicate via long range wireless communication with a component that is not worn by said patient.

13. The device of claim 12, further comprising a component that is not worn by said patient, wherein said component comprises a computing device with wireless capacity and connection to a network.

14. The device of claim 1, wherein said optical source of coherent light comprises a laser.

15. The device of claim 1, wherein said optical connection comprises an optical fiber bundle.

16. The device of claim 1, wherein said non-transitory medium comprises a plate.