Apparatus and method of fluid aspiration

• US 9,357,950 B2
• Filed: 11/15/2011
• Issued: 06/07/2016
• Est. Priority Date: 06/03/2009
• Status: Active Grant

• Current Assignee: Biometrix, Ltd. (Q Holding Company)
• Original Assignee: Biometrix, Ltd. (Q Holding Company)
• Inventors: Mendels, Yair, Uziel, Elad, Matan, Shamir, Revzin, Ilya, Rubinstein, Eldad Gabriel, Aframian, Vered, Gershuni, Yehonatan, Marco, Orga
• Primary Examiner(s): Dougherty, Sean
• Assistant Examiner(s): Leedy, Megan
• Application Number:
  US13/296,327
• Publication Number:
  US 20120123298A1
• Time in Patent Office: 1,666 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/1427 Multiple blood sampling, e.g. at periodic or pre-established intervals
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150862 intermediate range, e.g. within room or building
• CPC Class Codes: A61B 5/150946 Means for varying, regulating, indicating or limiting the speed or time of blood collection
• CPC Class Codes: A61B 5/150992 Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves tubing connectors and couplings A61M39/00
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: A61B 5/155 Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals devices loaded with multiple lancets simultaneously A61B5/15146
• CPC Class Codes: A61M 2005/14533 cam actuated
• CPC Class Codes: A61M 2039/0009 Assemblies therefor designed for particular applications, e.g. contrast or saline injection, suction or irrigation
• CPC Class Codes: A61M 2039/0018 designed for flushing a line, e.g. by a by-pass
• CPC Class Codes: A61M 2206/11 Laminar flow
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

An in-line sampling system that includes a sampling valve and a syringe for selectively introducing a fluid to and aspirating a fluid from a downstream fluid conduit connected to a catheterized patient. The syringe has a fluid chamber into which fluid is aspirated, a volume regulator for adjusting the volume, a fluid line through which fluid flows through the syringe to a downstream fluid conduit. The syringe also has a valve mechanism for selectively controlling fluid flow along the fluid line and selectively shifting the volume regulator to adjust the volume of the fluid chamber. A housing provides for the fluid chamber and mounts the fluid line, valve mechanism and volume regulator.

Claims

1. An in-line sampling syringe for selectively introducing a fluid to and aspirating a fluid from a downstream fluid conduit connected to a catheterized patient, said syringe comprising:

a. a housing defining a closed system composed of a fluid chamber having a first opening into which fluid is aspirated and an air chamber having a second opening in which a relief element is positioned;

b. a volume regulator mounted in said housing composed of a sealing gasket interposed between the fluid chamber and the air chamber and a drive mechanism connected to the sealing gasket for moving the sealing gasket for adjusting the volume of said fluid chamber;

c. a rigid fluid line mounted in a fixed position in said housing through which fluid flows relative to a downstream fluid conduit via said first opening, said rigid fluid line passing through the sealing gasket in a slidably sealed manner, and said rigid fluid line terminating adjacent to said first opening;

d. wherein said drive mechanism connected to the sealing gasket is mounted for linear sliding movement in said housing relative to said rigid fluid line; and

e. a rotatably mounted control member, which can be operated manually single handedly, is operatively connected to said drive mechanism for;

i. selectively controlling fluid flow relative to said rigid fluid line; and

, ii. selectively linearly shifting said volume regulator relative to said housing to adjust the volume of said fluid chamber.

2. The syringe of claim 1 wherein the relief element is one of a filter and a resilient membrane.

3. The syringe of claim 2 wherein the filter has properties of one of antimicrobial and antibacterial.

4. The syringe of claim 1, wherein the drive mechanism is a rack and pinion mechanism.

5. The syringe of claim 4, further including a shaft mounted for pivoting that is coupled with one end of an elongated handle the other end of the elongated handle being free, said shaft being coupled to rotate said pinion of said rack and pinion mechanism, said elongated handle being rotatable single-handedly.

6. The syringe of claim 5 wherein a scale marked with indicia is mounted on the housing and the free end of said elongated handle defines a pointer that coacts with the indicia on the scale to show precise correlated volume of aspirated fluid.

7. The syringe of claim 1, wherein the rigid fluid line comprises a first end in communication the fluid chamber and a second end in communication with a third opening to said housing.

8. The syringe of claim 1 further including a pressure transducer operatively mounted relative to said housing to sense pressure in one of said rigid fluid line and the first opening to said housing whereby an occlusion affecting the downstream fluid conduit connected to a catheterized patient can be sensed and detected;

detection circuitry operatively connected to receive pressure signals from said pressure transducer and in response thereto to signal detection of an occlusion by at least one of a display and audible alarm activated response.

9. The syringe of claim 8 further including a zeroing arrangement for the pressure transducer.

10. The syringe of claim 1 wherein the rotatably mounted control member includes a holding mechanism for detachably holding the rotatably mounted control member in a preselected position.

11. The syringe of claim 1 wherein one end of the termination of the rigid fluid line adjacent to said first opening is embedded in the housing at the first opening, for stability, with channels formed in the housing surrounding the embedded terminal end to enable fluid to flow from the first opening around the embedded terminal end into the housing.

12. In combination an in-line sampling system for selectively introducing a fluid to and aspirating a fluid from a downstream fluid conduit connected to a catheterized patient, comprising:

the syringe of claim 1;

a sampling port having a stopcock valve having a first port for connecting to a downstream fluid conduit connected to a catheterized patient, a second port connected to a sampling site for sampling and a third porter with the syringe according to claim 1 having its first opening via a downstream fluid conduit connected to the third port of the stopcock valve;

said rigid fluid line mounted in a fixed position in the housing of the syringe being connectable to a flushing fluid supply;

a controlling pressurizing mechanism for applying pressure to the flushing fluid supply;

a motor connected to the stopcock valve to control its position; and

an electronic controller operatively controlling said motor to position the stopcock valve to effect a monitoring step;

a flushing step, an aspirating step and a sampling step.

13. The combination according to claim 12 further including a pressure measuring mechanism for monitoring fluid pressure in said in-line sampling system.

14. The combination according to claim 12 wherein the electronic controller is operative for controlling monitoring of the patient blood pressure through the in-line sampling system, aspirating blood from a patient to the sampling valve for blood sampling and flushing fluid from the syringe back to the patient.

15. The combination according to claim 14 wherein the electronic controller includes one motor operatively coupled to the syringe, a second motor operatively coupled to the stopcock valve with the electronic controller automatically synchronizing the stopcock valve of the sampling port with the syringe, and automatically stepping through a monitoring operation, an aspirating operation, a sampling operation and a flushing operation.

16. The combination according to claim 12 wherein the pressurizing mechanism for applying pressure to a flushing fluid supply-includes a pressure cuff and a pump to apply pressure to the cuff and a valve to relieve pressure from the cuff.

17. The combination according to claim 12 further including a pressure transducer to monitor the pressure of fluid inside the system to provide an indication of the patient blood pressure.