Electrode configuration for implantable modulator

• US 9,358,392 B2
• Filed: 01/05/2015
• Issued: 06/07/2016
• Est. Priority Date: 09/30/2011
• Status: Active Grant

• Current Assignee: Man & Science S.A.
• Original Assignee: Adi Mashiach
• Inventors: Mashiach, Adi
• Primary Examiner(s): Gedeon, Brian T
• Assistant Examiner(s): TEJANI, ANKIT D
• Application Number:
  US14/589,938
• Publication Number:
  US 20150335879A1
• Time in Patent Office: 519 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 2562/164 the sensor is mounted in or on a conformable substrate or carrier
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/113 occurring during breathing
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61F 5/566 Intra-oral devices
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0504 Subcutaneous electrodes
• CPC Class Codes: A61N 1/0514 Electrodes for the urinary tract
• CPC Class Codes: A61N 1/0526 Head electrodes A61N1/0551 takes precedence
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0548 Oral electrodes
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/3601 : of respiratory organs
• CPC Class Codes: A61N 1/3605 : Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36057 : adapted for stimulating afferent nerves
• CPC Class Codes: A61N 1/3606 : adapted for a particular treatment
• CPC Class Codes: A61N 1/36075 : Headache or migraine
• CPC Class Codes: A61N 1/3611 : Respiration control stimulating respiratory organs A61N1/3601
• CPC Class Codes: A61N 1/36117 : for treating hypertension
• CPC Class Codes: A61N 1/36125 : Details of circuitry or electric components
• CPC Class Codes: A61N 1/36135 : using physiological parameters
• CPC Class Codes: A61N 1/36139 : with automatic adjustment
• CPC Class Codes: A61N 1/36146 : specified by the stimulation parameters
• CPC Class Codes: A61N 1/37211 : Means for communicating with stimulators
• CPC Class Codes: A61N 1/37223 : Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37229 : Shape or location of the implanted or external antenna
• CPC Class Codes: A61N 1/37235 : Aspects of the external programmer
• CPC Class Codes: A61N 1/37264 : Changing the program; Upgrading firmware
• CPC Class Codes: A61N 1/3727 : characterised by the modulation technique
• CPC Class Codes: A61N 1/3756 : Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3787 : from an external energy source
• CPC Class Codes: A61N 2/006 : for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/02 : using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence
• CPC Class Codes: F04C 2270/0421 : Controlled or regulated

Abstract

A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.

Claims

1. A head pain management device, comprising:

an implantable flexible carrier configured for location beneath skin of a head of a subject; and

a pair of electrodes located on the carrier and configured for implantation beneath skin of a substantially haired region of the head of the subject in a vicinity of an occipital nerve, wherein the electrodes are spaced from each other by a distance greater than 3 mm, and are configured to facilitate, when supplied with an electrical signal, a substantially unidirectional electric field sufficient to modulate the occipital nerve.

2. The head pain management device of claim 1, wherein the modulation of the occipital nerve includes a modulation signal sufficient to reduce pain signals carried by the occipital nerve.

3. The head pain management device of claim 1, wherein the substantially unidirectional field facilitated by the pair of electrodes extends through tissue interposed between the pair of electrodes and the occipital nerve.

4. The head pain management device of claim 3, wherein the pair of electrodes and the occipital nerve are spaced apart by a distance of at least 5 mm.

5. The head pain management device of claim 1, wherein the flexible carrier comprises attachment points configured for securing the flexible carrier to a surface of tissue beneath the skin of the head.

6. The device of claim 1, wherein the electrodes are configured to cause, when supplied with an electrical signal via an implantable circuit, a unidirectional electrical field.

7. The device of claim 1, wherein the electrodes are configured to modulate the occipital nerve when non-nerve tissue is interposed between the electrodes and the occipital nerve.

8. The device of claim 1, wherein the electrodes are configured with a spacing distance such that the unidirectional electrical field is sufficient to modulate the occipital nerve located greater than 1 mm away from the electrodes.

9. The device of claim 1, wherein the flexible carrier includes attachment points configured for securing the flexible carrier to a surface of the non-nerve tissue.

10. The device of claim 1, wherein the flexible carrier further comprises an insulative coating, and

wherein the electrodes are exposed on one side of the flexible carrier.

11. The device of claim 1, further comprising at least one pair of additional electrodes.

12. The device of claim 1, further comprising an antenna electrically coupled with an implantable circuit, wherein the antenna is adapted to receive a transmitted alternating current signal;

wherein the implantable circuit includes a converter configured to convert the alternating current signal into a direct current signal for delivery to the at least one pair of implantable electrodes.

13. The device of claim 12, wherein the implantable circuit is located on the flexible carrier, and wherein the antenna is located on the flexible carrier.