System for collecting samples and method for collecting a liquid sample

• US 9,364,172 B2
• Filed: 04/10/2009
• Issued: 06/14/2016
• Est. Priority Date: 10/12/2006
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Inventors: Konya, Ahmet, Deck, Frank, Ebert, Karl-Peter
• Primary Examiner(s): Eiseman, Adam J
• Assistant Examiner(s): FERNANDES, PATRICK M
• Application Number:
  US12/422,021
• Publication Number:
  US 20090270763A1
• Time in Patent Office: 2,622 Days
• Field of Search: 600/567, 600/583, 600/562, 600/564, 606/181, 606/182
• US Class Current: 1/1
• CPC Class Codes: A61B 5/1411 by percutaneous method, e.g. by lancet
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15128 comprising 2D- or 3D-shaped elements, e.g. cams, curved guide rails or threads comprising tooth-shaped elements A61B5/15132
• CPC Class Codes: A61B 5/15146 Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means. multiple simultaneous cutting or piercing A61B5/150977
• CPC Class Codes: A61B 5/15153 Multiple piercing elements stocked in a single compartment

Abstract

The invention relates to a system for collecting samples and to a method for collecting a liquid sample. The system comprises at least one analytical aid, the analytical aid comprising a lancet and a test element, and the test element having a test field for analysis of the liquid sample. The system for collecting samples comprises a coupling element which can be successively connected to the lancet, in a first position of the analytical aid, and to the test element, in a second position of the analytical aid. The system for collecting samples also comprises a drive unit for moving the coupling element from a rest position to a deployed position, such that the movement of the coupling element is transmitted to the lancet, coupled thereto, in order to execute a puncturing movement, or is transmitted to the test element, coupled thereto, in order to execute a sample recovery movement.

Claims

1. A system for collecting liquid samples, comprising:

a housing;

several analytical aids, each analytical aid comprising a lancet and a test element having a test field for analysis of a liquid sample wherein the lancet and the test element are disposed on a support;

a coupling element wherein the support of each analytical aid is positionable in first and second positions relative to the coupling element to thereby respectively define first and second positions of the analytical aid; and

a drive unit configured to move the coupling element from a rest position to a deployed position, a selected one of the analytical aids being moveable relative to the coupling element from the first position to the second position when the coupling element is in the rest position and wherein during the movement of the coupling element from the rest position to the deployed position when the one analytical aid is positioned in the first position, the coupling element is connectable to the lancet of the one analytical aid to execute a puncturing movement, and during the movement of the coupling element from the rest position to the deployed position when the one analytical aid is positioned in the second position, the coupling element is connectable to the test element of the one analytical aid to execute a sample recovery movement.

2. The system of claim 1, further comprising a transport device for transporting the support of the analytical aid from the first position to the second position relative to the coupling element arranged in the rest position.

3. The system of claim 1, wherein the drive unit comprises a mechanical energy reservoir that can output energy to and move the coupling element to the deployed position.

4. The system of claim 3, wherein the mechanical energy reservoir comprises a spring.

5. The system of claim 3, wherein the drive unit comprises a motor for charging the mechanical energy reservoir.

6. The system of claim 3, wherein, during charging of the mechanical energy reservoir, the drive unit transmits energy to the coupling element to execute the sample recovery movement of the test element.

7. The system of claim 3, wherein the drive unit comprises a mechanical movement converter and the coupling element is connected to the mechanical energy reservoir via the mechanical movement converter.

8. The system of claim 7, wherein the mechanical movement converter is configured to transmit energy of the mechanical energy reservoir to the coupling element to execute the puncturing movement of the lancet.

9. The system of claim 7, wherein the mechanical movement converter comprises a slide body having a guide slot into which an engagement element arranged on the coupling element engages.

10. The system of claim 9, wherein the mechanical energy reservoir and a motor are connected to the slide body via a drive element, wherein energy of the mechanical energy reservoir is transmitted to and moves the slide body in a first direction relative to the coupling element, and, during the charging of the mechanical energy reservoir, energy of the motor is transmitted to and moves the slide body relative to the coupling element in a second direction counter to the first direction.

11. The system of claim 7, wherein the mechanical movement converter comprises a connecting rod and a drive rotor which interact with the coupling element, wherein a rotating movement of the drive rotor is converted into a linear movement of the coupling element.

12. The system of claim 11, wherein the mechanical energy reservoir and a motor are connected to the drive rotor, wherein energy of the mechanical energy reservoir is transmitted to and rotates the drive rotor in a first direction, and, during charging of the mechanical energy reservoir, energy of the motor is transmitted to and rotates the drive rotor in a second direction counter to the first direction.

13. The system of claim 1, wherein the several analytical aids are received on an analysis tape, on a multiplicity of analytical aids, on a transport tape, in a magazine, or on a test element disk.

14. A system for collecting liquid samples, comprising:

a housing;

an analytical aid having a lancet and a test element disposed on a support;

a mechanical energy reservoir which outputs energy to the lancet to execute a puncturing movement; and

a transmission connected to the mechanical energy reservoir and to a coupling member, the coupling member and the support of the analytical aid being movable relative to each other wherein the coupling member is selectively couplable with the lancet and the test element wherein the mechanical energy reservoir outputs energy through the transmission to drive the lancet when the coupling member is coupled with the lancet and, wherein movement of the transmission simultaneously transmits energy to the mechanical energy reservoir to charge the mechanical energy reservoir and drives a sample recovery movement of the test element when the coupling member is coupled with the test element.

15. The system of claim 14, wherein the transmission in a first movement transmits energy of the mechanical energy reservoir to the lancet to execute the puncturing movement, and in a second movement simultaneously transmits energy to charge the mechanical energy reservoir and moves the test element.

16. The system of claim 15, wherein the first movement is faster than the second movement.

17. The system of claim 14, wherein the transmission comprises a connecting rod drive or a slide body with a guide slot.

18. A system for collecting liquid samples, comprising:

a housing;

a lancet;

a drive unit for driving the lancet such that the lancet can emerge at least partially from the housing in order to execute a puncturing movement, the drive unit comprising;

a mechanical energy reservoir which outputs energy to execute a puncturing movement with the lancet;

a mechanical movement converter, the lancet being connected to the mechanical energy reservoir via the mechanical movement converter, the mechanical movement converter comprising a connecting rod operably coupled with a drive rotor wherein the drive rotor is operably coupled with the mechanical energy reservoir and the connecting rod is operably couplable with the lancet, a rotating movement of the drive rotor being transmitted through the connecting rod and converted into a linear movement of the lancet, wherein a rotation movement of the drive rotor in one direction is transmitted to charge the mechanical energy reservoir and a rotation movement of the drive rotor in the other direction is transmitted by the connecting rod to the lancet to execute the puncturing movement.

19. The system of claim 18, further comprising a motor for charging the mechanical energy reservoir.

20. The system of claim 18, wherein the movement converter or the motor is connected to a further system function which is independent of the mechanical energy reservoir.

21. The system of claim 20, wherein the system function independent of the mechanical energy reservoir comprises at least one function from the following group:

execution of a sample recovery movement of a test element, transporting of an analytical aid comprising the lancet, transporting of a test element, and transporting of a test element magazine.

22. The system of claim 20, wherein the independent system function is actuated at the same time as the charging of the mechanical energy reservoir.

30. The system of claim 18 wherein the mechanical movement converter is configured to couple with a test element when the drive rotor is rotated in the one direction to charge the mechanical energy reservoir and thereby convert rotational movement of the drive rotor in the one direction to linear movement of the test element and execute a sample recovery movement.

23. A method for collecting a liquid sample in a sample-collecting system having a housing by means of at least one analytical aid, the analytical aid comprising a lancet and a test element, the lancet and the test element being disposed on a support, and the test element having a test field for analysis of the liquid sample, the method comprising the following steps:

connecting a coupling element of the system to the lancet when the support of the analytical aid is positioned in a first position;

moving the coupling element with a drive unit from a rest position to a deployed position when the coupling element is coupled to the lancet with the support of the analytical aid in the first position to thereby move the lancet in a puncturing movement;

moving the support of the analytical aid relative to the coupling element from the first position to a second position and then connecting the coupling element to the test element when the support of the analytical aid is positioned in the second position; and

moving the coupling element with the drive unit from the rest position to the deployed position when the coupling element is coupled to the test element to thereby execute a sample recovery movement.

24. The method of claim 23, wherein the moving of the coupling element with the drive unit comprises moving the coupling element to move the lancet in the puncturing movement and then moving the coupling element to move the test element to execute the sample recovery movement.

25. The method of claim 23, further comprising:

recovering the liquid sample onto the analytical aid by driving the coupling element connected to the test element in order to execute the sample recovery movement; and

at the same time charging a mechanical energy reservoir with energy to drive a puncturing movement of the lancet connected to the coupling element;

wherein the coupling element is connected successively to the lancet and to the test element, further wherein the coupling element is moved from a rest position to a deployed position and back to the rest position in both the puncturing movement and in the sample recovery movement.

26. A method for collecting a liquid sample in a sample-collecting system having a housing by means of an analytical aid, the analytical aid comprising a lancet and a test element wherein the lancet and the test element are disposed on a support, the method comprising connecting a coupling member with the lancet and outputting energy from a mechanical energy reservoir to the coupling member through a transmission to drive the lancet in a puncture movement;

moving the support of the analytical aid relative to the coupling member and connecting the coupling member to the test element and then moving the transmission to charge the mechanical energy reservoir with energy in order to drive a subsequent puncturing movement and wherein movement of the transmission simultaneously moves the test element in a sample recovery movement.

27. The method of claim 26, further comprising:

driving a coupling element connected to the test element in order to execute a sample recovery movement and thereby recovering a liquid sample; and

at the same time charging a mechanical energy reservoir with energy to drive a puncturing movement of the lancet connected to the coupling element;

wherein the coupling element is connected successively to the lancet and to the test element, further wherein the coupling element is moved from a rest position to a deployed position and back to the rest position in both the puncturing movement and in the sample recovery movement.

28. A method of executing a puncturing movement, the method comprising:

providing a housing with a drive unit couplable with a lancet, wherein the drive unit comprises a mechanical energy reservoir and a mechanical movement converter, the mechanical movement converter comprising a drive rotor operably couplable with the mechanical energy reservoir and operably couplable with a connecting rod;

rotating the drive rotor in a first rotational direction to charge the mechanical energy reservoir; and

after charging the mechanical energy reservoir, releasing stored energy from the mechanical energy reservoir to rotate the drive rotor in a second rotational direction opposite the first rotational direction to thereby impart motion to the connecting rod while the connecting rod is operably coupled with the lancet, the connecting rod converting the rotational movement of the drive rotor in the second rotational direction into linear movement of the lancet to thereby execute a puncturing movement.

29. The method of claim 28 wherein the lancet is provided as a part of an analytical aid wherein the analytical aid further comprises a test element and wherein the method further comprises:

uncoupling the lancet from the connecting rod after completing the puncture movement;

moving the analytical aid relative to the housing after uncoupling the lancet from the connecting rod;

rotating the drive rotor in the first direction to recharge the mechanical energy reservoir and simultaneously transmit movement to the connecting rod;

operably coupling the connecting rod with the test element as the drive rotor is rotated in the second rotational direction and using the connecting rod to convert the rotational movement of the drive rotor in the second rotational direction to linear movement of the test element and thereby execute a sample recovery movement.