Ventricular volume reduction

• US 9,364,327 B2
• Filed: 03/20/2015
• Issued: 06/14/2016
• Est. Priority Date: 10/26/2009
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Cardiokinetix Incorporated
• Inventors: Kermode, James R., Alexander, Miles D., Boutillette, Michael P., Davila, Matthew T., Tan, Irene Bing Bie
• Primary Examiner(s): LACYK, JOHN P
• Application Number:
  US14/664,684
• Publication Number:
  US 20150182338A1
• Time in Patent Office: 452 Days
• Field of Search: 600 16- 18, 600/37
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/0053 Loading magazines or sutures into applying tools
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 25/0067 characterised by the distal end, e.g. tips A61M25/0054, A61M25/04 take precedence; balloon catheters A61M25/10
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 60/17 inside a ventricle, e.g. intraventricular balloon pumps
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/289 Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices
• CPC Class Codes: A61M 60/295 Balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/468 the force acting on the actuation means being hydraulic or pneumatic
• CPC Class Codes: A61M 60/47 the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
• CPC Class Codes: A61M 60/497 for balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/833 Occluders for preventing backflow
• CPC Class Codes: A61M 60/861 Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body
• CPC Class Codes: A61M 60/865 Devices for guiding or inserting pumps or pumping devices into the patient's body
• CPC Class Codes: A61M 60/867 using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter

Abstract

Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient'"'"'s heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.

Claims

1. A ventricular volume reduction implant for insertion into a ventricle to reduce an active volume of the ventricle, the implant having a collapsed configuration that may be passed through a cannula and an expanded configuration spanning a portion of the ventricle, the implant comprising:

a plurality of flattened leaves extending outwards from a central hub, wherein in the expanded configuration the leaves are configured to form a partitioning barrier across the ventricle, wherein the leaves are discrete from each other; and

a plurality of anchors at the distal edge of the partitioning barrier configured to secure the partitioning barrier to the walls of the ventricle.

2. The implant of claim 1, wherein the leaves are coupled to the central hub and configured to fan out from a collapsed configuration into an overlapping expanded configuration to form the partitioning barrier.

3. The implant of claim 1, wherein the leaves are hinged to each other along a radial length of each leaf.

4. The implant of claim 3, wherein the leaves are hinged with square joints.

5. The implant of claim 3, wherein the leaves are hinged with triangular joints.

6. The implant of claim 3, wherein the leaves are hinged with sinusoidal joints.

7. The implant of claim 1, further comprising a foot extending from the central hub.

8. The implant of claim 1, wherein the leaves are overlapping in the collapsed configuration.

9. The implant of claim 1, wherein the leaves comprise a laminated membrane.

10. The implant of claim 1, wherein the leaves are made of metal.

11. The implant of claim 1, wherein the leaves are made of plastic.

12. An implant having a collapsed configuration and an expanded configuration, the implant comprising:

a central hub; and

a plurality of flattened plates extending from the central hub, wherein the plates are discrete from each other, wherein the plates are overlapping in the collapsed configuration and fanned out in the expanded configuration, wherein in the collapsed configuration the implant is configured to be delivered percutaneously through a delivery catheter and in in the expanded configuration the implant is configured to partition a chamber in a heart.

13. The implant of claim 12, further comprising a foot extending form the central hub.

14. The implant of claim 12, wherein the plates are hinged to each other.

15. The implant of claim 12, further comprising anchors configured to secure the implant within the chamber in the heart.

16. The implant of claim 12, wherein the plates are made of plastic.

17. The implant of claim 12, wherein the plates are made of metal.

18. The implant of claim 12, wherein the plates comprise a laminated membrane.