Piperidino-pyrimidine derivatives for the treatment of viral infections

• US 9,365,571 B2
• Filed: 08/04/2015
• Issued: 06/14/2016
• Est. Priority Date: 02/08/2012
• Status: Active Grant

• Current Assignee: Janssen Sciences Ireland UC (Johnson & Johnson)
• Original Assignee: Janssen Sciences Ireland UC (Johnson & Johnson)
• Inventors: McGowan, David Craig, Raboisson, Pierre Jean-Marie Bernard, Jonckers, Tim Hugo Maria, Daoubi Khamlichi, Mourad
• Primary Examiner(s): Balasubramanian, Venkataraman
• Application Number:
  US14/818,094
• Publication Number:
  US 20150336955A1
• Time in Patent Office: 315 Days
• Field of Search: 544/279, 514/264.1
• US Class Current: 1/1
• CPC Class Codes: A61K 31/519 ortho- or peri-condensed with heterocyclic rings
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 31/12 Antivirals
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
• CPC Class Codes: C07D 471/04 Ortho-condensed systems

Abstract

This invention relates to piperidino-pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.

Claims

1. A compound selected from the group consisting of:

2. A pharmaceutical composition comprising a pharmaceutically acceptable excipient and an effective amount of a compound selected from the group consisting of: