Sample cartridge and device for measuring electrical characteristics of liquid sample

• US 9,366,663 B2
• Filed: 08/25/2011
• Issued: 06/14/2016
• Est. Priority Date: 09/01/2010
• Status: Active Grant

• Current Assignee: Sony Corporation (Sony Group Corp.)
• Original Assignee: Sony Corporation (Sony Group Corp.)
• Inventors: Hayashi, Yoshihito, Katsumoto, Yoichi
• Primary Examiner(s): Alexander, Lyle
• Assistant Examiner(s): EOM, ROBERT J
• Application Number:
  US13/217,918
• Publication Number:
  US 20120048732A1
• Time in Patent Office: 1,755 Days
• US Class Current: 1/1
• CPC Class Codes: G01N 27/026 Dielectric impedance spectroscopy electrochemical impedance spectroscopy for measuring corrosion G01N17/02
• CPC Class Codes: G01N 33/4905 Determining clotting time of blood by chemical methods G01N33/86, C12Q1/54
• CPC Class Codes: G01N 33/86 involving blood coagulating time or factors, or their receptors

Abstract

A sample cartridge for measuring the electrical characteristics of a liquid sample, which is made by forming an insulating material into a tubular body and is capable of holding the liquid sample in a region that is constituted by the surfaces of electrodes that are respectively inserted from openings of both ends into an inner cavity and the surface of the inner cavity, and in which a narrowing portion located between two facing electrodes and having a narrowed inner cavity is provided in the region.

Claims

1. A sample cartridge for measuring the electrical characteristics of a liquid sample, the sample cartridge being made by forming an insulating material into a tubular body having a first end and a second end,

wherein the sample cartridge is configured to hold the liquid sample in a region that is defined by:

(1) outer surfaces of two electrodes that face each other and are respectively inserted within an inner cavity of the tubular body between the first and second ends and (2) a first surface and a second surface of the inner cavity that face each other, and

wherein a narrowing portion comprising a narrowed inner cavity is provided between the outer surfaces of the two electrodes, wherein the narrowing portion is formed by (1) a first partition wall that protrudes to the inner cavity side from at least a first portion of the first surface of the inner cavity of the tubular body and (2) a second partition wall that protrudes to the inner cavity side from at least a second portion of the second surface of the inner cavity of the tubular body,

wherein the first partition wall and the second partition wall are formed opposite to each other and face each other,

wherein the first surface of the inner cavity and the second surface of the inner cavity are formed between the outer surfaces of the two electrodes facing each other.

2. The sample cartridge according to claim 1, wherein a cross-sectional area of the narrowed inner cavity of the narrowing portion is smaller than an area of each of the outer surfaces of the two electrodes facing each other.

3. The sample cartridge according claim 1, wherein the narrowing portion is in contact with the outer surfaces of the two electrodes facing each other.

4. The sample cartridge according claim 1, wherein the insulating material comprises a hydrophobic polymer, copolymer or blend polymer containing a polymer selected from the group consisting of:

polypropylene, polymethylmethacrylate, polystyrene and polytetrafluoroethylene.

5. The sample cartridge according claim 1, wherein the narrowing portion is formed of the insulating material used to form the tubular body.

6. A sample cartridge for measuring the electrical characteristics of a liquid sample, comprising:

a tubular body formed of an insulating material and having a first end and a second end; and

two electrodes which face each other and are respectively inserted within an inner cavity of the tubular body between the first and second ends,

wherein the sample cartridge is configured to hold the liquid sample in a region that is defined by outer surfaces of the two electrodes facing each other and a first surface and a second surface of the inner cavity of the tubular body that face each other, and

wherein a narrowing portion comprising a narrowed inner cavity is provided between the outer surfaces of the two electrodes, wherein the narrowing portion is formed by (1) a first partition wall that protrudes to the inner cavity side from at least a first portion of the first surface of the inner cavity of the tubular body and (2) a second partition wall that protrudes to the inner cavity side from at least a second portion of the second surface of the inner cavity of the tubular body,

wherein the first partition wall and the second partition wall are formed opposite to each other and face each other,

wherein the first surface of the inner cavity and the second surface of the inner cavity are formed between the outer surfaces of the two electrodes facing each other.

7. A device for measuring the electrical characteristics of a liquid sample, comprising:

a pair of electrodes configured to apply voltage to the liquid sample;

a sample cartridge which is made by forming an insulating material into a tubular body having a first end and a second end and is configured to hold the liquid sample in a region that is defined by;

(1) outer surfaces of the electrodes that face each other and are respectively inserted within an inner cavity of the tubular body between the first and second ends, and (2) a first surface and a second surface of the inner cavity that face each other, and

wherein a narrowing portion comprising a narrowed inner cavity is provided between the outer surfaces of the pair of electrodes, wherein the narrowing portion is formed by (1) a first partition wall that protrudes to the inner cavity side from at least a first portion of the first surface of the inner cavity of the tubular body and (2) a second partition wall that protrudes to the inner cavity side from at least a second portion of the second surface of the inner cavity of the tubular body,

wherein the first partition wall and the second partition wall are formed opposite to each other and face each other,

wherein the first surface of the inner cavity and the second surface of the inner cavity are formed between the outer surfaces of the pair of electrodes facing each other;

an applying section configured to apply voltage to the pair of electrodes; and

a measuring section configured to measure the electrical characteristics of the liquid sample.

8. The device according to claim 7, wherein the measuring section is configured to measure the electrical characteristics of the liquid sample present in the narrowed inner cavity.

9. A blood coagulation system analysis device comprising:

a pair of electrodes configured to apply voltage to blood;

a sample cartridge which is made by forming an insulating material into a tubular body having a first end and a second end and is configured to hold the blood in a region that is defined by;

(1) outer surfaces of the pair of electrodes that face each other and are inserted within an inner cavity of the tubular body between the first and second ends, and (2) a first surface and a second surface of the inner cavity that face each other, and

wherein a narrowing portion comprising a narrowed inner cavity is provided between the outer surfaces of the pair of electrodes, wherein the narrowing portion is formed by (1) a first partition wall that protrudes to the inner cavity side from at least a first portion of the first surface of the inner cavity of the tubular body and (2) a second partition wall that protrudes to the inner cavity side from at least a second portion of the second surface of the inner cavity of the tubular body,

wherein the first partition wall and the second partition wall are formed opposite to each other and face each other,

wherein the first surface of the inner cavity and the second surface of the inner cavity are formed between the outer surfaces of the pair of electrodes facing each other;

an applying section configured to apply alternating-current voltage to the pair of electrodes; and

a measuring section configured to measure the permittivity of the blood.

10. The blood coagulation system analysis device according to claim 9, wherein the measuring section is configured to measure the permittivity of the blood present in the narrowed inner cavity.