Angle distribution technique for analyzing a physiological sensor signal

• US 9,370,308 B2
• Filed: 05/01/2012
• Issued: 06/21/2016
• Est. Priority Date: 05/01/2012
• Status: Active Grant

• Current Assignee: Nellcor Puritan Bennett Ireland
• Original Assignee: Nellcor Puritan Bennett Ireland
• Inventors: Addison, Paul, Ochs, James, Watson, James
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US13/461,002
• Publication Number:
  US 20130296659A1
• Time in Patent Office: 1,512 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02108 from analysis of pulse wave characteristics
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

The present disclosure relates generally to patient monitoring systems and, more particularly, to signal analysis for patient monitoring systems. In one embodiment, a method of analyzing a detector signal of a physiological patient sensor includes obtaining the detector signal from the physiological patient sensor, and determining a ratio of the signal between two or more channels. A distribution of the angles between the points of the ratio over time may be used to determine a true ratio or a ratio of ratios for use in the determination of a physiological parameter.

Claims

1. A method for determining a physiological parameter, comprising:

using a processor;

receiving a signal from a sensor, wherein the signal comprises at least two components;

determining a plurality of angles formed by a respective plurality of individual points of a Lissajous plot derived from the at least two components and wherein the angles comprise angles formed between a first line passing through an initial point selected from the plurality of individual points of the Lissajous plot and a second line passing through an individual point selected from another of the plurality of individual points of the Lissajous plot and the initial point;

determining a distribution of the angles; and

determining a physiological parameter based at least in part on the distribution of the angles.

2. The method of claim 1, wherein the Lissajous plot is derived from a logarithm of the components of the signal.

3. The method of claim 1, wherein determining the physiological parameter based on the distribution of the angles comprises determining a peak or mean of the distribution or a combination thereof.

4. The method of claim 1, wherein the physiological parameter comprises a blood oxygen saturation.

5. The method of claim 1, wherein the physiological parameter comprises a measure of arrhythmia.

6. The method of claim 1, wherein determining a physiological parameter of a patient comprises determining a pulse rate, respiration rate, respiration effort, continuous non-invasive blood pressure, cardiac output, fluid responsiveness, perfusion, pulse rhythm type, hydration level, or any combination thereof.

7. The method of claim 1, wherein the at least two components comprise an infrared channel and a red channel.

8. The method of claim 1, comprising determining a signal quality metric by comparing a signal quality of the signal received from the sensor to a predetermined threshold.

9. The method of claim 8, comprising determining the distribution of the angles when the signal quality is below the predetermined threshold.

10. The method of claim 9, comprising determining the physiological parameter based at least in part on the distribution of the slopes when the signal quality is above the predetermined threshold.

16. The method of claim 1, wherein the Lissajous plot is derived from a wavelet transform.

11. A patient monitoring system, comprising:

a patient monitor comprising a processor configured to;

receive a plethysmographic signal from a sensor;

determine a plurality of ratio values related to the signal at a plurality of time points;

determine a distribution of gradients between the plurality of ratio values;

determine angles between each of the plurality of ratio values based at least in part on a position of the plurality of ratio values relative to one another;

determine a distribution of the angles;

compare a first mean and/or peak ratio value determined based on the distribution of the angles to a second mean and/or peak ratio value determined based on the distribution of gradients;

determine a physiological parameter based at least in part on the distribution of the angles; and

determine a confidence of a value of the physiological parameter based on the comparing of the first mean and/or peak value to the second mean and/or peak value.

12. The system of claim 11, wherein the processor is configured to determine a signal quality of the plethysmographic waveform signal based on a difference between the first mean and/or peak ratio value and the second mean and/or peak ratio value.

13. The system of claim 11, wherein the processor is configured to determine a second physiological parameter based at least in part on the distribution of gradients between the plurality of ratio values.

14. The system of claim 11, wherein the processor is configured to determine the physiological parameter based at least in part on the distribution of gradients between the plurality of ratio values if a signal quality metric is above a predetermined threshold and wherein the processor is configured to determine the physiological parameter based at least in part on the distribution of the angles if the signal quality metric is below the predetermined threshold.

15. The system of claim 11, wherein the patient monitor comprises a display configured to provide an indication related to the physiological parameter.