Modulators of aldehyde dehydrogenase and methods of use thereof
First Claim
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1. A method of treating an ALDH-mediated disorder comprising administering to individual in need thereof a compound of Formula I:
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Abstract
The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.
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25 Claims
- 1. A method of treating an ALDH-mediated disorder comprising administering to individual in need thereof a compound of Formula I:
Specification