Steerable medical guide wire device

• US 9,370,640 B2
• Filed: 01/04/2013
• Issued: 06/21/2016
• Est. Priority Date: 09/12/2007
• Status: Active Grant

• Current Assignee: Kemet Electronics Corporation (Yageo Corporation)
• Original Assignee: Novasentis, Inc. (Yageo Corporation)
• Inventors: Zhang, Shihai, Davis, Stephen, Levatich, Mark, Ducharme, Richard
• Primary Examiner(s): Roane, Aaron
• Application Number:
  US13/734,866
• Publication Number:
  US 20130123692A1
• Time in Patent Office: 1,264 Days
• Field of Search: 600/114, 600/117, 600/143, 600/145, 600/146, 600/151, 600/152, 604/95.01, 606/1
• US Class Current: 1/1
• CPC Class Codes: A61L 2420/08 Coatings comprising two or more layers
• CPC Class Codes: A61L 31/048 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/0058 having an electroactive polymer material, e.g. for steering purposes, for control of flexibility, for locking, for opening or closing
• CPC Class Codes: A61M 2025/0063 having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness
• CPC Class Codes: A61M 25/0045 multi-layered, e.g. coated coating materials A61L29/08
• CPC Class Codes: A61M 25/0158 with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09041 Mechanisms for insertion of guide wires
• CPC Class Codes: C08L 27/14 Homopolymers or copolymers of vinyl fluoride
• CPC Class Codes: C08L 27/16 Homopolymers or copolymers or vinylidene fluoride
• CPC Class Codes: C08L 27/18 Homopolymers or copolymers or tetrafluoroethene

Abstract

A steerable guide wire including one or more electroactive polymer layers, wherein each EAP layer is disposed between a layer of a first electrode and a layer of a plurality of second electrodes.

Claims

1. A medical device in a guide wire form, comprising:

one or more sections provided along the length of the guide wire form, divided lengthwise into one or more sections, each section comprising;

one or more layers of a first electrode, wherein at least one of the layers of the first electrode includes a part of an electrode that extends an entire length of the guide wide form;

one or more layers of a second electrode; and

a plurality of electroactive polymer (EAP) layers, wherein each EAP layer is disposed between a layer of the first electrode and a layer of the second electrode, each EAP layer being activated by a voltage across the corresponding layer of the first electrode and the corresponding layer of the second electrode, and wherein the one or more layers of the first electrode, and wherein a first group of the EAP layers and the second group of the EAP layers are independently activated to cause a bending of the guide wire form in a predetermined direction or to achieve a predetermined shape for the guide wire form.

2. The medical device of claim 1, wherein each of the one or more layers of the second electrode include a plurality of second electrodes disposed in a given pattern.

3. The medical device of claim 1, wherein second electrodes in the same layer are aligned with each other.

4. The medical device of claim 1, wherein corresponding second electrodes in different layers are aligned with each other.

5. The medical device of claim 1, wherein the EAP comprises:

at least one monomer of vinylidene-fluoride;

at least one monomer selected from the group consisting of trifluoroethylene and tetrafluoroethylene; and

at least one monomer selected from the group consisting of tetrafluoroethylene vinyl fluoride, perfluoro (methyl vinyl ether), bromotrifluorethylene, chlorofluoroethylene, chlorotrifluoroethylene, and hexafluoropropylene.

6. The medical device of claim 1, wherein a portion of the medical device comprises:

a first layer of the first electrode including a core;

a first EAP layer conformally disposed on the first layer of the first electrode; and

a first layer of the second electrode conformally disposed on the first EAP layer.

7. The medical device of claim 1, further comprising:

an EAP layer disposed between a layer of the first electrode and a layer of the second electrode as a sheet rolled or folded into the guide wire form factor; and

wherein a given pattern of the second electrode comprises a pattern in the direction that the sheet is rolled or folded such that portions of the second electrode are aligned in a stack.

8. The medical device of claim 1, wherein each of a plurality of the EAP layers are disposed between alternating layers of the first electrode and second electrode in a stack.

9. A medical device comprising:

a guide wire including;

one or more layers of a first electrode, wherein at least one of the layers of the first electrode includes an electrode that extends an entire length of the guide wide;

one or more layers of a plurality of second electrodes; and

a plurality of electroactive polymer layers, wherein each electroactive polymer layer is disposed between a layer of a first electrode and a layer of a plurality of second electrodes, each electroactive polymer layer being activated by a voltage across the corresponding layer of the first electrode and the corresponding layer of the second electrode, and wherein the one or more layers of the first electrode, the one or more layers of the plurality of second electrode and the plurality of electroactive polymer layers are arranged in a guide wire form, and wherein at least a first group of the electroactive polymer layers and the second group of the electroactive polymer layers are independently activated to cause a bending of the guide wire form in a predetermined direction or to achieve a predetermined shape for the guide wire form; and

a drive unit coupled to the guide wire to generate one or more potential voltages and to apply each of the one or more potential voltages respectively across one or more sets of the first electrode and the second electrode.

10. The medical device of claim 9, wherein the guide wire further includes a core, wherein a stack of the plurality of electroactive polymer are disposed around at least a portion of the core.

11. The medical device of claim 9, wherein:

a single electroactive polymer layer is disposed between a single layer of the first electrode and a single layer of the plurality of second electrodes as a sheet rolled or folded into the guide wire form factor;

wherein a given pattern of the second electrodes comprises a geometrically expanding pattern in the direction that the sheet is rolled or folded such that corresponding second electrodes are radially aligned in a stack.

12. The medical device of claim 9, wherein the guide wire form includes a lumen through the one or more layers of the first electrode, the one or more layers of the plurality of second electrode and the plurality of electroactive polymer layers.

13. The medical device of claim 9, wherein the one or more potential voltages respectively applied across one or more sets of the first electrode and second electrode causes a deflection in the guide wire form.

14. The medical device of claim 9, wherein the one or more potential voltages respectively applied across one or more sets of the first electrode and second electrode causes a change in the rigidity of the guide wire form.

15. A device comprising:

a guide wire including a plurality of active EAP portions arranged in multiple stacks, wherein the active EAP portions in each stack are aligned with each other, each EAP portion comprising an EAP layer between a layer of a first electrode and a layer of a second electrode, each EAP layer being activated by a voltage across the corresponding layer of first electrode and the corresponding layer of the second electrode, and wherein a first stack of the active EAP portions and the second stack of the active EAP portions are independently activated to cause a bending of the guide wire in a predetermined direction or to achieve a predetermined shape for the guide wire, wherein an electrode in a layer of the first electrode extends an entire length of the guide wide; and

a drive unit, coupled to the guide wire, to generate one or more potential voltages and applied to each of the one or more generated voltages to one or more active EAP portions to control one or more physical parameters of the guide wire.

16. The device according to claim 15, wherein the one or more generated voltages applied by the drive unit to the one or more active EAP portions of the guide wire control a deflection of the guide wire.

17. The device according to claim 15, wherein the one or more generated voltages applied by the drive unit to the one or more active EAP portions of the guide wire control a rigidity of the guide wire.

18. The device according to claim 15, wherein the guide wire comprises:

a core;

a first layer of the first electrode formed on the core;

a first layer of EAP formed on the first layer of the first electrode;

a first layer of a plurality of the second electrodes formed on the first layer of EAP;

a second layer of EAP formed on the first layer of the plurality of the second electrodes; and

a second layer of the first electrode formed on the second layer of EAP.

19. The device according to claim 15, wherein the guide wire comprises a rolled or folded sheet including:

a layer of a first electrode disposed on a first side of a electroactive polymer layer; and

a layer of a plurality of second electrodes disposed on a second side of the EAP layer, wherein the plurality of second electrodes are arranged in a geometrically expanding pattern in a direction that the sheet is rolled or folded.

20. The device according to claim 15, wherein the EAP comprises:

at least one monomer of vinylidene-fluoride;

at least one monomer selected from the group consisting of trifluoroethylene and tetrafluoroethylene; and

at least one monomer selected from the group consisting of tetrafluoroethylene vinyl fluoride, perfluoro (methyl vinyl ether), bromotrifluorethylene, chlorofluoroethylene, chlorotrifluoroethylene, and hexafluoropropylene.