Unfiltered radiation therapy

• US 9,370,672 B2
• Filed: 02/20/2007
• Issued: 06/21/2016
• Est. Priority Date: 02/21/2006
• Status: Active Grant

• Current Assignee: University of Toledo
• Original Assignee: University of Toledo
• Inventors: Parsai, E. Ishmael, Feldmeier, John J.
• Primary Examiner(s): Artman, Thomas R
• Application Number:
  US12/224,015
• Publication Number:
  US 20110033028A1
• Time in Patent Office: 3,409 Days
• Field of Search: 378/65
• US Class Current: 1/1
• CPC Class Codes: A61N 2005/1034 Monte Carlo type methods; particle tracking
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: A61N 5/1045 using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT
• CPC Class Codes: A61N 5/1077 Beam delivery systems
• CPC Class Codes: G21K 1/046 varying the contour of the field, e.g. multileaf collimators
• CPC Class Codes: G21K 5/00 Irradiation devices discharge tubes for irradiating H01J37/00

Abstract

This is a new technique in IMRT and 3D conformal gamma radiation dose delivery using a linear accelerator with no flattening filter. The technique improves patient radiation therapy by reducing radiation scattered to surrounding normal tissue and reducing electron contamination. It increases dose rate to shorten treatment time. Linear accelerators have for decades come with a photon flattening filter to make the photon profile of planar fluence to make the dose distribution more uniform. These filters, however, resulted in fluence attenuation and contamination of the beam. Now in the age of techniques such as intensity modulated radiation therapy (IMRT) the function of the flattening filter becomes redundant. The flattening filter now merely reduces the efficiency of the beam by reducing the fluence and increasing scattered radiation. Our technique involves removal of the flattening filter for complex treatments. It uses inverse planning along with multi-leaf collimators to shape the dose distribution.

Claims

1. A radiation therapy device comprising:

a radiation source that directs an unmodulated raw beam along a beam path toward a selected treatment zone;

wherein the radiation source is a linear accelerator without a flattening filter to provide a high radiation dose;

wherein the radiation dose is high energy X-rays ranging from 6 MV to 25 MV;

a beam shaping device controllable to selectively collimate the unmodulated raw beam including at least one multi-leaf collimators (MLC); and

a treatment planning system for delivering an Intensity Modulated Radiation Therapy (IMRT) by utilizing the raw unmodulated beam having a predetermined profile of the high energy radiation dose and using the MLC to shape and modulate the raw beam profile for a particular dose distribution, wherein by not using a flattening filter, the MLC is configured to apply a predetermined modulation of the high energy radiation dose to be applied to the predetermined treatment zone.

2. The radiation device of claim 1, wherein the modulated beam has a higher photon fluence compared to a flattened beam.