Identification of pressure cuff conditions using frequency content of an oscillometric pressure signal

• US 9,375,150 B2
• Filed: 04/25/2012
• Issued: 06/28/2016
• Est. Priority Date: 04/25/2012
• Status: Active Grant

• Current Assignee: Summit Doppler Systems Incorporated
• Original Assignee: Summit Doppler Systems Incorporated
• Inventors: Jarrell, Kenneth E., Jones, David C.
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): Ramachandran, Vasuda
• Application Number:
  US13/455,967
• Publication Number:
  US 20130289421A1
• Time in Patent Office: 1,525 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

A method, system and computer program product are provided for evaluating whether an oscillometric signal representative of pressure oscillations in the vasculature of a patient is associated with special conditions that may lead to inadvertently identifying the signal as being indicative of peripheral arterial disease or non-analyzable. In one embodiment, the method includes obtaining an oscillometric signal at a location on an extremity of the patient, determining a ratio using a value associated with a first frequency component of the oscillometric signal and a value associated with a second frequency component of the oscillometric signal, comparing the ratio to a threshold value, associating a first diagnostic class with the oscillometric signal when a first outcome results from comparing the ratio to a threshold value, and associating a second diagnostic class with the oscillometric signal when a second outcome results from comparing the ratio to a threshold value.

Claims

1. A method for evaluating whether an oscillometric signal representative of pressure oscillations in the vasculature of a patient is associated with special conditions, said method comprising:

obtaining, from a blood pressure cuff, an oscillometric signal at a location on an extremity of the patient;

determining, using a processor, a ratio using a value associated with a first frequency component of the oscillometric signal and a value associated with a second frequency component of the oscillometric signal;

comparing, using the processor, the ratio to a threshold value;

associating, using the processor, a first diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a first outcome of the comparison to the threshold value results from said comparing the ratio to a threshold value;

associating, using the processor, a second diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a second outcome of the comparison to the threshold value results from said comparing the ratio to a threshold value, wherein the first diagnostic class is characterized as the patient having a first severity of peripheral arterial disease and the second diagnostic class is characterized as the patient having a second severity of peripheral arterial disease;

selecting, using the processor, a characteristic ratio based on the diagnostic class associated with the oscillometric signal;

applying, using the processor, the characteristic ratio to a maximum amplitude of the oscillometric signal to determine an adjusted amplitude value of the oscillometric signal; and

correlating, using the processor, the adjusted amplitude value of the oscillometric signal to a pressure in the blood pressure cuff to determine an indicated blood pressure value for the patient.

2. The method according to claim 1, wherein the extremity comprises a lower extremity.

3. The method according to claim 2, wherein the location on the lower extremity comprises an ankle.

4. The method according to claim 1 wherein the first outcome of the comparison to the threshold value comprises the ratio being less than the threshold value, and wherein the second outcome of the comparison to the threshold value comprises the ratio being greater than or equal to the threshold value.

5. The method according to claim 1 further comprising:

transforming the oscillometric signal from a time domain representation into a frequency domain representation; and

identifying the first frequency component and the second frequency component from the frequency domain representation of the oscillometric signal.

6. The method according to claim 5 wherein said transforming the oscillometric signal comprises performing a Fourier transform operation.

7. The method according to claim 5 wherein the value associated with the first frequency component comprises an amplitude of the first frequency component in the frequency domain, and wherein the value associated with the second frequency component comprises an amplitude of the second frequency component in the frequency domain.

8. The method according to claim 5 wherein the first frequency component comprises the fundamental frequency of the oscillometric signal in the frequency domain and wherein the second frequency component comprises the second harmonic frequency of the oscillometric signal in the frequency domain.

9. The method according to claim 1 wherein said steps of said method are included within a process for evaluating the presence of peripheral arterial disease in a patient using an oscillometric signal obtained at a lower extremity of the patient.

10. A system operable to evaluate whether an oscillometric signal representative of pressure oscillations in the vasculature of a patient is associated with special conditions, said system comprising:

a pressure applicator positionable at a location on an extremity of a patient, said pressure applicator being controllable to apply a pressure to occlude blood flow in a portion of the extremity and to reduce the pressure applied thereby to permit blood flow to return in the portion of the extremity;

a processor in operative communication with said pressure applicator;

a pressure transducer in operative communication with said pressure applicator to obtain an oscillometric signal from the extremity as pressure applied by the pressure applicator to the extremity is reduced, wherein said pressure transducer is in operative communication with said processor; and

a special conditions evaluation module executable by said processor, said special conditions evaluation module being operable to;

determine a ratio using a value associated with a first frequency component of the oscillometric signal and a value associated with a second frequency component of the oscillometric signal;

compare the ratio to a threshold value;

associate a first diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a first outcome of the comparison to the threshold value results from comparing the ratio to a threshold value;

associate a second diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a second outcome of the comparison to the threshold value results from comparing the ratio to a threshold value, wherein the first diagnostic class is characterized as the patient having a first severity of peripheral arterial disease and the second diagnostic class is characterized as the patient having a second severity of peripheral arterial disease;

select a characteristic ratio based on the diagnostic class associated with the oscillometric signal;

apply the characteristic ratio to a maximum amplitude of the oscillometric signal to determine an adjusted amplitude value of the oscillometric signal; and

correlate the adjusted amplitude value of the oscillometric signal to a pressure in the pressure applicator to determine an indicated blood pressure value for the patient.

11. A computer program product for evaluating whether an oscillometric signal representative of pressure oscillations in the vasculature of a patient is associated with special conditions, said computer program product comprising:

a non-transitory computer readable medium having computer readable program code embodied therein, the computer readable program code including;

computer readable program code enabling a processor to obtain, from a blood pressure cuff, an oscillometric signal at a location on an extremity of the patient;

computer readable program code enabling a processor to determine a ratio using a value associated with a first frequency component of the oscillometric signal and a value associated with a second frequency component of the oscillometric signal;

computer readable program code enabling a processor to compare the ratio to a threshold value;

computer readable program code enabling a processor to associate a first diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a first outcome of the comparison to the threshold value results from comparing the ratio to a threshold value;

computer readable program code enabling a processor to associate a second diagnostic class from a plurality of diagnostic classes with the oscillometric signal when a second outcome of the comparison to the threshold value results from comparing the ratio to a threshold value, wherein the first diagnostic class is characterized as the patient having a first severity of peripheral arterial disease and the second diagnostic class is characterized as the patient having a second severity of peripheral arterial disease;

computer readable program code enabling a processor to select a characteristic ratio based on the diagnostic class associated with the oscillometric signal;

computer readable program code enabling a processor to apply the characteristic ratio to a maximum amplitude of the oscillometric signal to determine an adjusted amplitude value of the oscillometric signal; and

computer readable program code enabling a processor to correlate the adjusted amplitude value of the oscillometric signal to a pressure in the blood pressure cuff to determine an indicated blood pressure value for the patient.