Systems and methods for providing beam scan patterns for high speed doppler optical frequency domain imaging

• US 9,375,158 B2
• Filed: 07/31/2008
• Issued: 06/28/2016
• Est. Priority Date: 07/31/2007
• Status: Active Grant

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Vakoc, Benjamin J., Tearney, Guillermo J., Bouma, Brett E.
• Primary Examiner(s): REMALY, MARK DONALD
• Application Number:
  US12/183,630
• Publication Number:
  US 20090036782A1
• Time in Patent Office: 2,889 Days
• Field of Search: 600/309, 600/310, 600/407, 600473-480, 356/39, 356/345, 356/346, 250/356.1, 250/363.01, 250/370.08
• US Class Current: 1/1
• CPC Class Codes: A61B 5/0066 Optical coherence imaging
• CPC Class Codes: A61B 5/0073 by tomography, i.e. reconstruction of 3D images from 2D projections A61B5/0066 takes precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light

Abstract

An exemplary apparatus and/or an exemplary method can be provided using which, it is possible (e.g., with at least one first arrangement) to measure an amplitude and/or a phase of at least one electromagnetic radiation provided from a particular portion of a sample. Further, it is possible (e.g., using at least one second arrangement) to scan a location of the particular portion along a path from a first point of the sample to a second point of the sample. In addition, it is possible to control the scan (e.g., with the second arrangement) such that the scan may comprise at least one first segment having a positive velocity and at least one segment having a negative velocity. A first distance of the first segment and/or the second segment can be smaller than a second distance between the first and second points.

Claims

1. An apparatus comprising:

at least one digitizer first arrangement configured to measure at least one of an amplitude or a phase of at least one electromagnetic radiation provided from a particular portion of a sample; and

at least one scanner second arrangement configured to perform a scan of a location of the particular portion along a path from a first point of the sample to a second point of the sample,

wherein the at least one second arrangement controls the scan such that the scan along the path comprises at least one segment in which a first portion of the scan is provided in a first direction and in which a second portion of the scan is returned in a second direction, wherein the scan of the at least one segment is repeated along exactly the same path, and wherein a first length along the path of the at least one segment is smaller than a second length along the path between the first and second points.

2. The apparatus according to claim 1, wherein the at least one second arrangement comprises at least one of a galvanometric reflecting arrangement or an acousto-optic deflecting arrangement.

3. The apparatus according to claim 1, wherein the at least one second arrangement performs the scan in less than about 200 msec.

4. The apparatus according to claim 1, wherein the at least one second arrangement performs the scan in less than about 50 msec.

5. The apparatus according to claim 1, wherein the at least one first arrangement is configured to receive an interference signal which is associated with the at least one electromagnetic radiation and at least one further radiation received from a reference.

6. The apparatus according to claim 1, further comprising a source arrangement which causes a frequency of the at least one electromagnetic radiation to change over time.

7. The apparatus according to claim 1, wherein at least one of the first length or the second length is less than a third length along the path from the first point to the second point.

8. The apparatus according to claim 1, wherein the sample includes a biological structure.

9. The apparatus according to claim 8, wherein the at least one first arrangement is configured to measure a blood flow within the sample.

10. The apparatus according to claim 8, wherein the at least one first arrangement is configured to determine a response by the biological sample to a treatment thereof.

11. The apparatus according to claim 1, wherein the path is transverse to a direction of a transmission of the at least one electromagnetic radiation.

12. A method comprising:

measuring at least one of an amplitude or a phase of at least one electromagnetic radiation provided from a particular portion of a sample;

performing a scan of a location of the particular portion along a path from a first point of the sample to a second point of the sample; and

controlling the scan such that the scan along the path comprises at least one segment in which a first portion of the scan is provided in a first direction and in which a second portion of the scan is returned in a second direction, wherein the scan of the at least one segment is repeated along exactly the same path, and wherein a first length along the path of the at least one segment is smaller than a second length along the path between the first and second points.

13. The method according to claim 12, wherein the scanning procedure is performed by at least one scanner arrangement which comprises at least one of a galvanometric reflecting arrangement or an acousto-optic deflecting arrangement.

14. The method according to claim 12, wherein a time of the scan is less than about 200 msec.

15. The method according to claim 12, wherein a time of the scan is less than about 50 msec.

16. The method according to claim 12, further comprising receiving an interference signal which is associated with the at least one electromagnetic radiation and at least one further radiation received from a reference.

17. The method according to claim 12, wherein a frequency of the at least one electromagnetic radiation changes over time.

18. The method according to claim 12, at least one of the first length or the second length is less than a third length along the path from the first point to the second point.

19. The method according to claim 12, wherein the sample includes a biological structure.

20. The method according to claim 19, further comprising measuring a blood flow within the sample.

21. The method according to claim 19, further comprising determining a response by the biological sample to a treatment thereof.

22. The method according to claim 12, wherein the path is transverse to a direction of a transmission of the at least one electromagnetic radiation.