Stent and living organ dilator

• US 9,375,329 B2
• Filed: 06/30/2014
• Issued: 06/28/2016
• Est. Priority Date: 09/27/2007
• Status: Active Grant

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Kabushiki Kaisha
• Inventors: Takayuki, Kito, Hiroki, Goto
• Primary Examiner(s): Shi, Katherine M
• Application Number:
  US14/319,399
• Publication Number:
  US 20140316512A1
• Time in Patent Office: 729 Days
• Field of Search: 623/1.15, 623/1.16, 623/1.38
• US Class Current: 1/1
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0031 made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts
• CPC Class Codes: A61F 2250/0071 breakable or frangible
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/128 containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: A61M 29/00 Dilators with or without means for introducing media, e.g. remedies instruments for performing visual medical inspections of cavities or tubes of the body A61B1/00

Abstract

A stent configured to closely contact tissue in vivo by being deformed when set indwelling in vivo. The stent has a plurality of axially arranged annular members, with axially adjacent annular members being interconnected by at least one link part; and a metallic wavy-linear annular member positioned at each end of the stent. The plurality of axially arranged annular members include a plurality of linear components, the linear components including a plurality of metallic linear components and a plurality of biodegradable material-made linear components. The at least one link part is defined by one of the metallic linear components. After a predetermined period of time when the stent is left indwelling in vivo and biodegradation of the biodegradable material-made linear components proceeds, the plurality of metallic linear components and the at least one link part remain intact such that a unitary metallic structure is maintained in vivo.

Claims

1. A stent configured to closely contact tissue in vivo by being deformed when set indwelling in vivo, the stent comprising:

a plurality of axially arranged annular members, with axially adjacent annular members being interconnected by at least one link part; and

a metallic wavy-linear annular member positioned at each end of the stent;

wherein said plurality of axially arranged annular members comprise a plurality of linear components configured to deform and exhibit a force for maintaining dilation when the stent is set indwelling in vivo, the linear components comprising a plurality of metallic linear components and a plurality of biodegradable material-made linear components;

wherein the at least one link part is defined by one of the metallic linear components; and

wherein, after a predetermined period of time when the stent is left indwelling in vivo and biodegradation of the biodegradable material-made linear components proceeds, the plurality of metallic linear components and the at least one link part remain intact such that a unitary metallic structure is maintained in vivo; and

wherein the metallic linear components are zigzag in shape and the biodegradable material-made linear components are zigzag in shape, the metallic linear components comprising a plurality of metallic linear spiral members extending in a spiral manner in relation to an axial direction of the stent, the plurality of metallic linear spiral members being interconnected by the biodegradable material-made linear components.

2. The stent according to claim 1, wherein the metallic linear spiral members extending in a spiral direction, the biodegradable material-made linear components each extending in a direction different from the spiral direction in which the metallic linear spiral members extend.

3. The stent according to claim 1, wherein the metallic linear components have at least one joint part which protrudes from the at least one link part in a direction of the biodegradable material-made linear components.

4. The stent according to claim 3, wherein the biodegradable material-made linear components envelop only a free end of the at least one joint part.

5. The stent according to claim 3, wherein an end portion of the biodegradable material-made liner component is joined to the at least one joint part.

6. The stent according to claim 1, wherein each annular member comprises a plurality of circumferentially arranged annular components surrounding a central axis of the stent and each elongated in an axial direction of the stent, each annular component possessing a centrally located opening and being in a collapsed form, with circumferentially adjacent annular components connected at a connection part, at least some of the connection parts connecting circumferentially adjacent annular components of a first annular member being connected by way of the link part to respective connection parts connecting circumferentially adjacent annular components of an axially adjacent second annular member, the connection parts and the link parts being composed of the metallic linear components, and at least some of the annular components each being configured such that one part of the annular component not connected to the connection part is composed of the biodegradable material-made linear component, while a remaining part is composed of the metallic linear component.

7. The stent according to claim 1, comprising means for restraining disconnection between the metallic linear component and the biodegradable material-made linear component, the means for restraining disconnection being positioned at a joint between the metallic linear component and the biodegradable material-made linear component.

8. The stent according to claim 1, wherein the biodegradable material-made linear components are connected to the metallic linear components at respective joints, the biodegradable material-made linear components covering an outer surface and/or an inner surface of the metallic linear component at the joint.

9. The stent according to claim 1, wherein the linear components deformed when the stent is set indwelling in vivo comprise a multiplicity of bent or curved more easily deformable parts which are deformed when the stent is set indwelling in vivo, and joint parts which join the more easily deformable parts and are less easily deformed when the stent is set indwelling, the more easily deformable parts being comprised of the metallic linear components, and the joint parts being comprised of the biodegradable material-made linear components.

10. The stent according to claim 9, wherein each joint part joins free ends of two respective more easily deformable parts.

11. The stent according to claim 9, wherein the joint parts and the more easily deformable parts include means for restraining disconnection of the more easily deformable parts and the respective joint parts.

12. The stent according to claim 9, wherein the joint part covers an outer surface and/or an inner surface of the more easily deformable part.

13. The stent according to claim 9, wherein the joint part covers an entire surface of the more easily deformable part.

14. The stent according to claim 1, wherein the metallic linear component is a plastically deformable metallic linear component, the stent is a tubular body possessing a diameter permitting insertion into a lumen in vivo, and the stent is expanded when a radially outwardly directed dilating force is exerted on the stent from inside the stent.

15. The stent according to claim 1, wherein the metallic linear component is a superelastic metallic linear component, the stent possesses a hollow cylindrical shape and is compressed in a direction of a center axis of the stent when inserted into a living body, and the stent expands externally to restore a pre-compression shape when left indwelling in vivo.

16. A living organ dilator comprising a tubular shaft body part, a foldable and dilatable balloon provided at a distal portion of the shaft body part, and the stent according to claim 14 which is positioned to cover the balloon in a folded state and which is expandable by expansion of the balloon.

17. A living organ dilator comprising a sheath and the stent according to claim 15 which is accommodated in a distal portion of the sheath, and an inner tube for pushing out the stent from a distal end of the sheath, the inner tube being slidably inserted in the sheath.