Syringe pump with improved flow monitoring

• US 9,375,531 B2
• Filed: 10/24/2012
• Issued: 06/28/2016
• Est. Priority Date: 10/27/2011
• Status: Active Grant

• Current Assignee: Zyno Medical, LLC
• Original Assignee: Zyno Medical, LLC
• Inventors: Lee, Chaoyoung, Zhang, Mei, Lu, Cunyou
• Primary Examiner(s): Stigell, Theodore
• Assistant Examiner(s): KOO, BENJAMIN K
• Application Number:
  US13/659,619
• Publication Number:
  US 20140114238A1
• Time in Patent Office: 1,343 Days
• Field of Search: 604 65- 67, 604/154, 604/131
• US Class Current: 1/1
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/16804 Flow controllers
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: A61M 5/16877 Adjusting flow; Devices for setting a flow rate
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence

Abstract

A syringe pump provides a controlled metering of the medicament from a syringe by movement of the syringe plunger while also measuring flow from the syringe with a flow sensor. Simultaneous monitoring of flow command implicit in control of the syringe plunger and an actual flow provides additional safety and detection of irregularities in the delivery of the medicament.

Claims

1. A syringe pump comprising:

a housing adapted to hold a syringe holding a liquid medicament;

a motor drive attached to the housing having a portion adapted to hold a plunger portion of the syringe to move the plunger portion within a tube portion of the syringe according to a motor drive signal to eject the medicament from the syringe;

a motor controller powering the motor drive to provide movement of the plunger portion within the tube portion at a controlled rate and a controlled distance and in communication with one or more sensors to provide a flow estimate of medicament from the syringe based on known dimensions of the syringe tube and operation of the motor controller;

a flow sensor adjacent to a flow of medicament from the syringe and adapted to measure the flow of the medicament through a downstream elastomeric IV tube in communication with the syringe; and

an electronic controller configured to (i) interrogate the flow sensor to determine the flow of medicament, (ii) determine an acceptable flow range around zero when the motor controller is not operating and around the flow estimate when the motor controller is activated, (iii) compare the flow of medicament with the acceptable flow range to detect a flow error arising from a difference between the flow of the medicament and the acceptable flow range, and (iv) deactivate or adjust the motor drive upon detection of the flow error;

wherein the flow sensor is adapted to releasably receive the elastomeric IV tube passing from the syringe to a patient and having substantially continuous tubing walls unbroken by the flow sensor, the flow sensor positioned entirely outside the tubing walls of the IV tube without piercing the IV tube and without contact with fluid within the IV tube;

further including a pressure sensor adapted to releasably receive the elastomeric IV tube, the pressure sensor positioned entirely outside the tubing walls of the IV tube without piercing the IV tube and without contact with the fluid within the IV tube indicate a pressure of the medicament within an IV line attached to the syringe and communicate the pressure to the electronic controller.

2. The syringe pump of claim 1 further including an alarm indicator for a user of the syringe pump and wherein the electronic controller activates the alarm upon detection of at least one of the flow error and a pressure error.

3. The syringe pump of claim 2 wherein the flow error is a flow rate outside of the acceptable flow range.

4. The syringe pump of claim 3 wherein the electronic controller provides a pump speed command to the motor drive and wherein the acceptable flow range is a function of pump speed command.

5. The syringe pump of claim 4 wherein the flow sensor deduces flow from pressure differential along a length of the IV tube.

6. The syringe pump of claim 4 wherein the flow sensor includes an ultrasonic transducer and ultrasonic receiver emitting and receiving ultrasonic sound and wherein the second flow sensor deduces flow through a change in ultrasonic transmission speed of the ultrasonic sound through the liquid medicament as measured along an axis of the tube.

7. The syringe pump of claim 4 wherein the flow sensor deduces flow through at least one of a change in tubing deformation or moving pattern of minor optical inclusions in the medicament by utilizing at least one optical sensor.

8. The syringe pump of claim 4 wherein the flow sensor is integrated into an IV tube attached to the syringe and communicating with a patient.

9. The syringe pump of claim 1 wherein the pressure sensor is a component of the flow sensor.

10. The syringe pump of claim 1 wherein the flow error is detected by comparing flow to the acceptable flow range being a function of whether the motor drive is moving the plunger portion.