Steerable ultrasound catheter

• US 9,381,027 B2
• Filed: 12/23/2013
• Issued: 07/05/2016
• Est. Priority Date: 08/26/2002
• Status: Active Grant

• Current Assignee: Flowcardia Inc. (Becton, Dickinson & Co)
• Original Assignee: Flowcardia Inc. (Becton, Dickinson & Co)
• Inventors: Nita, Henry, Sarge, Jeff
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US14/139,447
• Publication Number:
  US 20140180304A1
• Time in Patent Office: 925 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/22004 using mechanical vibrations, e.g. ultrasonic shock waves A61B17/225 takes precedence
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 17/320068 using mechanical vibrations, e.g. ultrasonic A61B17/22012 takes precedence; dental tooth drilling devices operated by vibration A61C3/03; removing intra-ocular material using mechanical vibrations A61F9/00745
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/22014 the ultrasound transducer being outside patient's body; with an ultrasound transmission member; with a wave guide; with a vibrated guide wire not applied in A61B17/22012
• CPC Class Codes: A61B 2017/308 with suction cups
• CPC Class Codes: A61B 2017/32007 with suction or vacuum means
• CPC Class Codes: A61B 2017/320071 with articulating means for working tip
• CPC Class Codes: A61M 25/0054 with regions for increasing flexibility

Abstract

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

Claims

1. An ultrasound catheter comprising:

a catheter body having a proximal portion, a distal portion, a longitudinal axis, and a lumen;

an ultrasound transmission member, having a distal end, extending longitudinally through the lumen of the catheter body, radially offset from the center of the catheter body;

a distal head coupled with the distal end of the ultrasound transmission member and disposed adjacent the distal portion of the catheter body;

a guidewire lumen extending through the distal head, the guidewire lumen having a smaller diameter portion at a distal end and a larger diameter portion at a proximal end, the larger diameter portion forming a cavity in the distal head; and

a guidewire tube extending through at least a portion of the catheter body radially offset from the center of the catheter body and extending through the distal head along an axis not parallel to the longitudinal axis of the catheter body, a distal end of the guidewire tube being disposed in the cavity in the distal head, wherein the distal end of the guide-wire lumen exits approximately at the center of the distal end of the distal head.

2. The ultrasound catheter of claim 1 wherein the guidewire tube is coupled to the distal head in the cavity.

3. The ultrasound catheter of claim 2 wherein the exterior surface of the guidewire tube is coupled to an interior wall of the cavity.

4. The ultrasound catheter of claim 3 wherein a distal edge of the guidewire tube is coupled to an abutment surface formed at the distal end of the cavity.

5. The ultrasound catheter of claim 4 wherein the abutment surface extends circumferentially around the guidewire lumen.

6. The ultrasound catheter of claim 3 wherein the guidewire tube extends through the distal head in a distal direction beyond the distal end of the ultrasound transmission member.

7. The ultrasound catheter of claim 6 further comprising at least one coupling member for coupling the ultrasound transmission member with a source of ultrasound energy.

8. The ultrasound catheter of claim 7 wherein the guidewire tube enters the lumen of the catheter body at an entry point that is proximal to the distal head and distal to the proximal portion of the catheter body.

9. The ultrasound catheter of claim 8 wherein the exterior surface of the guidewire tube is coupled with the catheter body at the entry point.

10. An ultrasound catheter comprising:

a catheter body having a proximal portion, a distal portion, a longitudinal axis, and a lumen;

an ultrasound transmission member extending longitudinally through the lumen of the catheter body;

a distal head having a proximal end and a distal end, the distal head being coupled with the ultrasound transmission member and disposed adjacent to the distal portion of the catheter body;

a guidewire lumen extending through the distal head along an axis not parallel to the longitudinal axis of the catheter body; and

a guidewire tube comprising an exterior surface and a distal edge, the guidewire tube extending through the lumen of the catheter body, radially offset from the center of the catheter body and extending through the guidewire lumen so that the distal edge of the guidewire tube abuts the distal end of the distal head, wherein the distal end of the guidewire lumen exits approximately at the center of the distal end of the distal head.

11. The ultrasound catheter of claim 10 wherein the guidewire tube is coupled to the distal head in the guidewire lumen.

12. The ultrasound catheter of claim 11 wherein the exterior surface of the guidewire tube is coupled to an interior wall of the guidewire lumen.

13. The ultrasound catheter of claim 12 wherein the guidewire tube extends through the distal head distally beyond the ultrasound transmission member.

14. The ultrasound catheter of claim 13 further comprising at least one member for coupling the ultrasound transmission member with a source of ultrasound energy.

15. The ultrasound catheter of claim 14 wherein the guidewire tube enters the lumen of the catheter body at an entry point that is proximal to the distal head and distal to the proximal portion of the catheter body.

16. The ultrasound catheter of claim 15 wherein the exterior surface of the guidewire tube is coupled with the catheter body at the entry point.

17. An ultrasound catheter comprising:

a catheter body having a proximal portion, a distal portion, a longitudinal axis, and a lumen;

an ultrasound transmission member disposed in the catheter body, radially offset from the center of the catheter body;

a head coupled to the ultrasound transmission member;

a guidewire tube extending through at least a portion of the catheter body radially offset from the center of the catheter body and extending through the head along an axis not parallel to the longitudinal axis of the catheter body; and

a guidewire lumen, the guidewire lumen forming an abutment surface in the head so as to contact an end of the guidewire tube to prevent movement of the guidewire tube in at least one direction relative to the head.

18. The ultrasound catheter of claim 17 further comprising a guidewire, the guidewire being disposed in the guidewire tube.