Systems, devices, and methods for quality assurance of radiation therapy
First Claim
Patent Images
1. A method for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device including a gantry, comprising:
- acquiring and converting 2D images in order togenerate radiation dose distribution images at predetermined radiation fields, each radiation field corresponding to a predetermined arc segment of the gantry;
comparing the generated radiation dose distribution images with corresponding predicted radiation dose distribution images using a three-dimensional (3D) gamma evaluation method, the comparing including;
calculating dose differences, spatial differences, and angular differences between points in the generated images and corresponding points in the predicted images; and
evaluating the calculated differences using a gamma error function, the gamma error function determining minimums of a metric comprising the calculated dose, spatial, and angular differences for the points evaluated in the generated image; and
determining acceptability of a quantity of interest based on a result of the evaluation.
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Abstract
Systems, devices, and methods for quality assurance for verification of radiation dose delivery in arc-based radiation therapy devices using a 3D gamma evaluation method.
17 Citations
31 Claims
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1. A method for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device including a gantry, comprising:
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acquiring and converting 2D images in order to generate radiation dose distribution images at predetermined radiation fields, each radiation field corresponding to a predetermined arc segment of the gantry; comparing the generated radiation dose distribution images with corresponding predicted radiation dose distribution images using a three-dimensional (3D) gamma evaluation method, the comparing including; calculating dose differences, spatial differences, and angular differences between points in the generated images and corresponding points in the predicted images; and evaluating the calculated differences using a gamma error function, the gamma error function determining minimums of a metric comprising the calculated dose, spatial, and angular differences for the points evaluated in the generated image; and determining acceptability of a quantity of interest based on a result of the evaluation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A system for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device including a gantry, comprising:
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a portal dose imaging device adapted to measure incident radiation dose from each predetermined radiation field, each radiation field corresponding to a predetermined arc segment of the gantry, the portal dose imaging device being further configured generate two-dimensional (2D) portal images for each arc segment; and a processing device operably connected to the portal dose imaging device and being configured to convert the 2D portal images to 2D portal dose images and to store a plurality of measured 2D portal dose image data in a first 3D data array including 3D position information of points in the measured 2D portal dose images, and having spatial and angular locations of the delivered beams (X, Y, θ
) as dimensions, the processing device being further configured to store a plurality of predicted 2D portal dose image data in a second 3D data array including 3D position information of points in the predicted 2D portal dose images, and having spatial and angular locations of the predicted beams (X, Y, θ
) as dimensions;the processing device being further configured to compare the points in the first 3D data array with corresponding points in the second 3D data array using a 3D gamma evaluation method, the gamma evaluation method including calculating dose differences, spatial differences, and angular differences between corresponding points in the first and second 3D data arrays as parameters; the processing device being further configured to evaluate the calculated differences using a gamma error function, the gamma error function determining minimums of a metric comprising the calculated dose, spatial, and angular differences for the points evaluated in the generated image, and to determine acceptability of a quantity of interest based on a result of the evaluation, wherein errors in the quantities of interest are determined based on the comparison. - View Dependent Claims (14, 15, 16, 17, 18)
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19. A non-transitory computer-readable storage medium upon which is embodied a sequence of programmed instructions for verifying quantities of interest of a radiation beam in a system including an arc-based radiation therapy device including a gantry and a computer processing system which executes the sequence of programmed instructions embodied on the computer-readable storage medium to cause the computer processing system to perform the steps of:
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acquiring and converting 2D images in order to generate radiation dose distribution images at predetermined radiation fields, each radiation field corresponding to a predetermined arc segment of the gantry; and comparing the generated radiation dose distribution images with corresponding predicted radiation dose distribution images using a three- dimensional (3D) gamma evaluation method including calculating dose differences, spatial differences, and angular differences between points in the generated images and corresponding points in the predicted images as parameters, wherein the comparing includes evaluating the calculated differences using a gamma error function, the gamma error function determining minimums of a metric comprising the calculated dose, spatial, and angular differences for the points evaluated in the generated image, and determining acceptability of a quantity of interest based on a result of the evaluation. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method for verifying quantities of interest of a radiation beam in an arc-based radiation therapy device including a gantry, comprising:
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delivering radiation at a plurality of radiation fields corresponding to a predetermined arc segment of the gantry; measuring transmitted or absorbed radiation from each arc segment using an electronic portal dose imaging device; generating 2D images based on the measured radiation; converting the 2D images into corresponding 2D portal dose images (PDIs) using a portal dose reconstruction model; and comparing the obtained 2D portal dose images with corresponding predicted radiation dose images using a three-dimensional (3D) gamma evaluation method including calculating dose differences, spatial differences, and angular differences between points in the generated images and corresponding points in the predicted images as parameters; evaluating the calculated differences using a gamma error function, the gamma error function determining minimums of a metric comprising the calculated dose, spatial, and angular differences for the points evaluated in the generated image; and determining acceptability of a quantity of interest based on a result of the evaluation.
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Specification