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Compositions and methods for modulating angiopoietin-like 3 expression

  • US 9,382,540 B2
  • Filed: 05/01/2015
  • Issued: 07/05/2016
  • Est. Priority Date: 05/01/2014
  • Status: Expired due to Fees
First Claim
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1. A compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 20 contiguous nucleobases complementary to an equal length portion of nucleobases 1140 to 1159 of SEQ ID NO:

  • 1, wherein the nucleobase sequence of the modified oligonucleotide is at least 80% complementary to SEQ ID NO;

    1; and

    wherein the conjugate group comprises;

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