Guidewire with adjustable stiffness

• US 9,387,309 B2
• Filed: 12/19/2012
• Issued: 07/12/2016
• Est. Priority Date: 04/23/2007
• Status: Active Grant

• Current Assignee: CardioGuidance Biomedical, LLC
• Original Assignee: CardioGuidance Biomedical, LLC
• Inventors: Parodi, Juan Carlos, Hinchliffe, Peter W. J., Lupton, Henry, Mooney, Ivan, Donohue, Colin
• Primary Examiner(s): Stout, Michael C
• Application Number:
  US13/719,319
• Publication Number:
  US 20130131644A1
• Time in Patent Office: 1,301 Days
• Field of Search: 600/585
• US Class Current: 1/1
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61M 2025/0006 which can be secured against axial movement, e.g. by using a locking cuff
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/09075 having a core without a coil possibly combined with a sheath
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 2025/09091 where a sheath surrounds the coil at the distal part
• CPC Class Codes: A61M 2025/09116 Design of handles or shafts or gripping surfaces thereof for manipulating guide wires
• CPC Class Codes: A61M 2025/09133 having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
• CPC Class Codes: A61M 2025/0915 having features for changing the stiffness
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09025 with sliding mandrils
• CPC Class Codes: A61M 25/09041 Mechanisms for insertion of guide wires
• CPC Class Codes: A61M 25/0905 extendable, e.g. mechanisms for extension
• CPC Class Codes: A61M 5/007 for contrast media

Abstract

A medical guidewire system including an inner member having an outer diameter and an outer member having an inner diameter, the inner diameter being larger than the outer diameter. The inner and outer members are relatively slidable to adjust a stiffness of the guidewire system. The lumen of the outer member forms a gap for fluid flow therethrough. A connector to the inner member and a fluid infusion channel communicating with the gap for injection of fluid through the gap to exit a distal portion of the outer member.

Claims

1. A method of using a guidewire system having adjustable rigidity in a patient, the method comprising:

a) providing a guidewire system having an inner wire member having a closed tip, a first outer diameter and a first stiffness, and an outer tube member having regions of different flexibility along its length and a stiffness different than the first stiffness of the inner wire member, the outer tube member having an inner diameter larger than the first outer diameter of the inner member, and a lumen for receiving the inner wire member, wherein the inner wire member and outer tube member are independently slideable relative to one another to change the overall diameter and stiffness of the guidewire system, and together functions as a unitary guidewire structure for guiding a medical device into the patient;

b) advancing the guidewire system with the inner wire member in a retracted position within the lumen of the outer tube member to thereby provide a more stiff distal portion of the guidewire system to increase pushability;

c) advancing the inner wire member within the lumen from the retracted position to an advanced position wherein a distal tip of the inner wire member extends distal of a distal end of the outer tube member to thereby provide a less stiff distal portion of the guidewire system to enhance flexibility;

d) selectively locking and, as needed, selectively unlocking the inner wire member and outer tube member at a proximal region of the outer tube member in a fixed position with respect to one another when the inner wire member is in one of the retracted and advanced positions relative to the outer tube member; and

e) selectively repeating steps b), c) or d) above as the guidewire system advances into the patient, wherein each repeated step achieves a desired degree of pushability, flexibility or stiffness in advancement of the guidewire system to a desired location, without a need to exchange the system or a portion thereof;

wherein the proximal region is operable to permit a device to be delivered along the guidewire system to the desired location.

2. The method of claim 1, wherein the step of selectively locking the inner wire member comprises the step of applying a clamping force on an outer surface of the inner wire member.

3. The method of claim 1, wherein the step of selectively locking the inner wire member comprises applying a clamping force on a tubular member positioned over a portion of the inner wire member.

4. The method of claim 3, further comprising the step of detaching the tubular member from the inner wire member for advancement of a catheter.

5. The method of claim 1, wherein the inner wire member and outer tube member each comprise a handle and further comprising the step of advancing a catheter over the handles.

6. The method of claim 1, further comprising the step of removing the outer tube member and inserting a catheter over the inner wire member.

7. The method of claim 6, further comprising the step of removing a handle of the inner wire member prior to the step of inserting a catheter over the inner wire member.