Test strip and methods and apparatus for reading the same

• US 9,390,237 B2
• Filed: 11/22/2013
• Issued: 07/12/2016
• Est. Priority Date: 11/22/2012
• Status: Active Grant

• Current Assignee: R-Biopharm AG (RMD Holding GmbH)
• Original Assignee: MicroLab Devices Ltd
• Inventors: Myers, Thomas Oliver, Davies, Thomas Oliver
• Primary Examiner(s): Lee, Seung
• Application Number:
  US14/646,698
• Publication Number:
  US 20150286803A1
• Time in Patent Office: 963 Days
• Field of Search: 235/375, 235/462.15
• US Class Current: 1/1
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

Embodiments of the present invention provide a method of analyzing a response of an analyte test device, comprising recording, by a device reading device, an image of coded test information associated with the test device, determining, based directly on the image of the test information, one or more test parameters, recording, by the reading device, an image of one or more optically responsive portions of the test device, and determining the response of the test device based on the one or more test parameters and the image of the one or more optically responsive portions of the test device.

Claims

1. A method of analysing a response of an analyte test device, comprising:

recording, by a reading device, an image of coded test information associated with the test device;

determining directly based on the image of the test information one or more test parameters, wherein the test parameters comprise location information for providing a location on the test device of one or more features;

recording, by the reading device, an image of one or more optically responsive portions of the test device; and

determining the response of the test device based on the one or more test parameters and the image of the one or more optically responsive portions of the test device, wherein the determining the response comprises applying a perspective transform to the image of the one or more optically responsive portions of the test device based on the location information.

2. The method of claim 1, wherein the perspective transform is a mathematical operation applied to the image of the optically responsive portions, such that the image appears to be viewed from another position.

3. The method of claim 1, wherein the test information comprises first and second registration marks.

4. The method of claim 3, wherein the perspective transform corrects for an attitude between the reading device and the test device based on the registration marks and distance points identified by the test information.

5. The method of claim 1, wherein the location information provides one or more of a distance and an angle between the test information to the one or more features.

6. The method of claim 5, wherein the distance is determined based on a length between first and second registration marks.

7. The method of claim 1, wherein the location information provides an initial estimate of a location of the one or more features of the test device.

8. The method of claim 7, comprising performing, by the reading device, a search process based on one or more search regions denoted by the location information.

9. The method of claim 7, wherein the test information provides a search radius within which the reading device is arranged to perform a search for a respective feature.

10. The method of claim 7, wherein the reading device is arranged to use a feature detection technique such as a Harris detector, FAST-ER or AGAST.

11. The method of claim 1, wherein the optically responsive portions are arranged to one of change colour and fluoresce in the presence of the analyte.

12. A reading device for analysing a response of an analyte test device, comprising:

an imaging device for recording images;

a software module which, when executed by a processor of the reading device is arranged to directly determine one or more test parameters based on an image of coded test information associated with a test device, wherein the parameters comprise location information for providing a location on the test device of one or more features, and to determine a response of the test device based on the one or more test parameters and an image of one or more optically responsive regions of the test device, wherein the determining the response comprises applying a perspective transform to the image of the one or more optically responsive portions of the test device based on the location information.

13. The reading device of claim 12, wherein the perspective transform is a mathematical operation applied to the image of the optically responsive portions, such that the image appears to be viewed from another position.

14. The reading device of claim 12, wherein the perspective transform corrects for an attitude between the reading device and the test device based on one or more registration marks and distance points identified by the test information.

15. The reading device of claim 12, wherein the location information provides one or more of a distance and an angle between the test information to the one or more features.

16. The reading device of claim 15, wherein the distance is determined based on a length between first and second registration marks.

17. The test device of claim 12, wherein the coded test information comprises configuration information for configuring a reading device to record the image of the one or more optically responsive portions of the test device.

18. The test device of claim 12, wherein the coded test information is provided by an optically readable data code.

19. The reading device of claim 12, wherein the software module is arranged to determine threshold information indicative of one or one or more test thresholds for the optically responsive portions based the test parameters, and to determine the response of the test device is based on the one or more test thresholds.

20. The reading device of claim 12, wherein the software module is arranged to record an image of one or more calibration regions, and to determine the response of the test device based in part on the image of the one or more calibration region.