Visualization and characterization of pulmonary lobar fissures

• US 9,390,498 B2
• Filed: 04/18/2015
• Issued: 07/12/2016
• Est. Priority Date: 10/11/2012
• Status: Active Grant

• Current Assignee: VIDA Diagnostics, Inc.
• Original Assignee: VIDA Diagnostics, Inc.
• Inventors: Yin, Youbing, Newell, John D. Jr., Raffy, Philippe, Wood, Susan A.
• Primary Examiner(s): Harandi, Siamak
• Application Number:
  US14/690,391
• Publication Number:
  US 20150294462A1
• Time in Patent Office: 451 Days
• Field of Search: None
• US Class Current: 1/1
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: G06T 19/20 Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• CPC Class Codes: G06T 2200/24 involving graphical user interfaces [GUIs]
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/30061 Lung
• CPC Class Codes: G06T 2210/41 Medical
• CPC Class Codes: G06T 2219/2012 Colour editing, changing, or manipulating; Use of colour codes
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

Systems and methods for visualizing pulmonary fissures including a processor and software instructions for creating a 3 dimensional model of the fissures. Creating the 3 dimensional model includes accessing volumetric imaging data of the patient'"'"'s lungs, analyzing the volumetric imaging data to segment the lungs into lobes, using the segmented lobes to identify locations at which pulmonary fissures should be present where the lobes abut each other, analyzing the volumetric images to identify locations at which pulmonary fissures actually are present as existing fissure, comparing the locations at which pulmonary fissures should be present to the locations at which pulmonary fissures are present to identify locations of missing fissure, and creating a visual display comprising a 3 dimensional model of the pulmonary fissures including existing fissure portions and missing fissure portions, with the existing fissure portion visually distinct from the missing fissure portions.

Claims

1. A system for visualizing pulmonary fissures of a person'"'"'s lungs comprising;

a processor;

software comprising instructions for the processor for creating a visual display comprising a two-dimensional model of the pulmonary fissures,

wherein creating a visual display comprising the two-dimensional model of the pulmonary fissures comprises;

accessing volumetric imaging data of the person'"'"'s lungs;

analyzing the volumetric imaging data to segment the lungs into lobes;

using the segmented lobes, identifying locations at which pulmonary fissures should be present as the locations where the lobes abut each other;

analyzing the volumetric images to identify locations at which pulmonary fissures are present as existing fissure;

comparing the identified locations at which pulmonary fissures should be present to the identified locations at which pulmonary fissures are present to identify locations of missing fissure; and

creating a visual display comprising the two-dimensional model of the pulmonary fissures comprising existing fissure portions and missing fissure portions, wherein the existing fissure portions are visually distinct from the missing fissure portions.

2. The system of claim 1 wherein the existing fissure portions are displayed in a different color than the missing fissure portions in the two-dimensional model of the pulmonary fissures.

3. The system of claim 2 wherein the software further comprises instructions to create a graphical user interface allowing a user to reclassify a location on the two-dimensional model of the pulmonary fissures from existing to missing or from missing to existing by interacting with the two-dimensional model of the pulmonary fissures on the graphical user interface.

4. The system of claim 2 wherein the two-dimensional model of the pulmonary fissures further comprises a two-dimensional representation of the lung parenchyma in combination with the fissures.

5. The system of claim 2 wherein the two-dimensional model of the pulmonary fissures further comprises a two-dimensional representation of a tumor in combination with the fissures, wherein the software further comprises instructions for identifying a location of the tumor by analyzing the volumetric imaging data.

6. The system of claim 5 wherein the software further includes instructions to calculate a distance between the tumor and a nearest fissure location.

7. The system of claim 1 wherein the software further comprises instructions for calculating a numerical value representing integrity of the fissures.

8. The system of claim 7 wherein the numerical value provides a relative proportion of amount of the fissures that is existing and amount of the fissures that is missing.

9. The system of claim 7 wherein the software further comprises instructions for calculating a numerical value representing integrity of a portion of a fissure abutting a lobe, wherein the portion of the fissure abutting the lobe is less than all of the fissure.

10. The system of claim 7 wherein the software further comprises instructions for calculating a numerical value representing integrity of a portion of a fissure abutting a sub-lobe.

11. The system of claim 1 wherein the software further comprises instructions for receiving directions from a user to reclassify a fissure location identified by the system as existing fissure to be identified and displayed as missing fissure in the two-dimensional model of the pulmonary fissures.

12. A system for visualizing pulmonary fissures of a patient'"'"'s lungs comprising;

a processor;

software comprising instructions for the processor for creating a visual display comprising a two-dimensional model of the pulmonary fissures,

wherein creating a visual display comprising the two-dimensional model of the pulmonary fissures comprises;

accessing volumetric imaging data of the patient'"'"'s lungs;

analyzing the volumetric imaging data to segment the lungs into lobes and sub-lobes;

using the segmented lobes, identifying locations at which pulmonary fissures should be present where the lobes abut each other;

analyzing the volumetric images to identify locations at which pulmonary fissures are present;

comparing the identified locations at which pulmonary fissures should be present to the identified locations at which pulmonary fissures are present to identify locations of missing fissure;

identifying portions of the present and missing fissures which abut the sub-lobes; and

creating a visual display comprising the two-dimensional model of the pulmonary fissures comprising existing fissure portions and missing fissure portions, wherein the existing fissure portions are visually distinct from the missing fissure portions and wherein the portions of the missing and existing fissures abutting the sub-lobes are visually distinct from each other.

13. The system of claim 12 wherein the existing fissure portions are displayed in a different color than the missing fissure portions in the two-dimensional model of the pulmonary fissures.

14. The system of claim 12 wherein the portions of the missing and existing fissures abutting the sub-lobes are each presented in a different color.

15. The system of claim 12 wherein the software further comprises instructions for calculating a numerical value representing integrity of the fissures, wherein the numerical value provides a relative proportion of amount of the fissures that is existing and amount of fissure that is missing.

16. The system of claim 15 wherein the numerical value representing integrity of the fissures is a calculation for the integrity of an entire fissure, of only a portion abutting a lobe, or only a portion of a fissure abutting a sub-lobe, wherein selection of the entire fissure, the portion abutting the lobe, or the portion abutting a sub-lobe can be determined by a user.

17. The system of claim 12 wherein the software further comprises instructions for receiving directions from a user interacting with the two-dimensional model of the pulmonary fissures on a graphical user interface to reclassify a fissure location identified by the system as existing fissure to be identified and displayed as missing fissure, and to reclassify a fissure location identified by the system as missing fissure to be identified and displayed as existing fissure.

18. A method for creating a two-dimensional model of pulmonary fissures of a patient comprising:

accessing volumetric imaging data of the patient'"'"'s lungs;

analyzing the volumetric imaging data to segment the lungs into lobes;

using the segmented lobes, identifying locations at which pulmonary fissures should be present as the locations where the lobes about each other;

analyzing the volumetric images to identify locations at which pulmonary fissures are present as existing fissure;

comparing the identified locations at which pulmonary fissures should be present to the identified locations at which pulmonary fissures are present to identify locations of missing fissure; and

displaying the two-dimensional model of the pulmonary fissures on a display, wherein the visual display comprises existing fissure portions and missing fissure portions, wherein the existing fissure portions are visually distinct from the missing fissure portions.

19. The method of claim 18 further comprising calculating a numerical value representing integrity of the fissures, wherein the numerical value provides a relative proportion of amount of the fissures that is existing and amount of fissure that is missing.

20. The method of claim 18 further comprising receiving directions from a user interacting with the two-dimensional model of the pulmonary fissures to reclassify a fissure location identified by the system as existing fissure to be identified and displayed as missing fissure, and to reclassify a fissure location identified by the system as missing fissure to be identified and displayed as existing fissure.