Devices and methods to treat vascular dissections

• US 9,393,100 B2
• Filed: 11/16/2011
• Issued: 07/19/2016
• Est. Priority Date: 11/17/2010
• Status: Active Grant

• Current Assignee: Endologix
• Original Assignee: Endologix
• Inventors: Schreck, Stefan G.
• Primary Examiner(s): Weisberg, Amy R
• Application Number:
  US13/988,175
• Publication Number:
  US 20130253632A1
• Time in Patent Office: 1,707 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61M 25/0043 characterised by structural features
• CPC Class Codes: A61M 25/01 Introducing, guiding, advancing, emplacing or holding catheters A61M25/10 takes precedence

Abstract

A device system and method for the treatment of aortic dissections comprising placing a stent in the true lumen and displacing the blood in the false lumen with an inflatable bag.

Claims

1. A method of treating an aortic dissection having a true lumen and a false lumen, comprising:

deploying a support structure in the true lumen of a blood vessel adjacent to or overlapping a portion of the dissection to maintain the true lumen in an open state;

advancing a bag in a collapsed state as part of a catheter with a fill lumen into the false lumen;

inflating the bag while said bag is in the false lumen using a filling medium provided to said bag through the fill lumen such that the bag conforms to an inner layer between the true lumen and the false lumen and covers a tear formed in the inner layer to block blood flow through the false lumen; and

separating the bag from the catheter while maintaining the bag in the false lumen.

2. The method of claim 1, wherein the support structure is a balloon expandable stent or a self-expandable stent.

3. The method of claim 1, comprising sealing at least one opening into the dissection with a support structure that is partially covered with a graft.

4. The method of claim 1, comprising inflating the bag with the filling medium comprising a polymer or monomer that crosslinks after injection.

5. The method of claim 4, wherein the polymer comprises polyethylene glycol.

6. The method of claim 1, wherein the bag is made from ePTFE, polyurethane, Dacron, woven or knitted biocompatible fibers, or other thin-wall biocompatible material.

7. The method of claim 1, wherein the bag comprises an embolization agent.

8. The method of claim 1, further comprising monitoring a pressure in the bag during inflation.

9. The method of claim 1, wherein the filling medium for inflating the bag is liquid during injection and changes phase to a solid after injection.

10. The method of claim 1, comprising inflating the bag to displace the blood in the false lumen after deploying the support structure in the true lumen of the blood vessel adjacent to or overlapping a portion of the dissection.

11. The method of claim 1, further comprising advancing the bag into the false lumen through an opening closer to a downstream end of the false lumen than an upstream end of the false lumen.

12. The method of claim 1, wherein inflating the bag comprises inflating the bag to a pressure in excess of systolic blood pressure.