Peripheral nerve field stimulation and spinal cord stimulation

• US 9,393,416 B2
• Filed: 12/30/2013
• Issued: 07/19/2016
• Est. Priority Date: 06/09/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Rooney, Ethan A., King, Gary W., Wahlstrand, Carl D., Heruth, Kenneth T., Cross, Thomas E. Jr., Wacnik, Paul W., Stone, Richard T.
• Primary Examiner(s): Heller, Tammie K
• Application Number:
  US14/144,307
• Publication Number:
  US 20140114374A1
• Time in Patent Office: 932 Days
• US Class Current: 1/1
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/0558 Anchoring or fixation means therefor
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

Delivery of peripheral nerve field stimulation (PNFS) in combination with one or more other therapies is described. The other therapy delivered in combination with PNFS may be, for example, a different type of neurostimulation, such as spinal cord stimulation (SCS), or a drug. PNFS and the other therapy may be delivered simultaneously, in an alternating fashion, according to a schedule, and/or selectively, e.g., in response to a request received from a patient or clinician. A combination therapy that includes PNFS may be able to more completely address complex or multifocal pain than would be possible through delivery of either PNFS or other therapies alone. Further, the combination of PNFS with one or more other therapies may reduce the likelihood that neural accommodation will impair the perceived effectiveness PNFS or the other therapies.

Claims

1. A system for treating pain of a patient comprising:

a first implantable medical device configured to deliver peripheral nerve field stimulation to a region of a body of the patient in which the patient experiences pain via a first set of one or more electrodes configured to be implanted in the region; and

a second implantable medical device configured to deliver spinal cord stimulation to the patient via a second set of one or more electrodes configured to be implanted proximate to a spinal cord of the patient.

2. The system of claim 1, wherein the first and second medical devices are configured to communicate to coordinate delivery of the peripheral nerve field stimulation and the spinal cord stimulation.

3. The system of claim 1, wherein the first implantable medical device comprises a housing configured to be implanted within the region of the body in which the patient experiences pain, and the first set of electrode comprises an array of electrodes located on the housing.

4. The system of claim 1, wherein the first implantable medical device is configured to be implanted within at least one of an intra-dermal, deep dermal, or subcutaneous layer of the region.

5. The system of claim 1, wherein the first and second implantable medical devices are configured to deliver stimulation substantially simultaneously.

6. The system of claim 1, wherein the first and second implantable medical devices are configured to alternate delivery the peripheral nerve field stimulation and the spinal cord stimulation.

7. The system of claim 1, wherein the first set of electrodes is configured to be implanted in an axial region of a back of the patient.

8. The system of claim 7, wherein the second set of electrodes is configured to be implanted within a region from a seventh thoracic vertebrae to a first lumbar vertebrae of the patient.

9. The system of claim 1, wherein the first set of electrodes is configured to be implanted proximate to a branch of a spinal nerve that originates in a region from a second cervical vertebrae to a third cervical vertebrae of the patient, and the second set of electrodes is configured to be implanted within a region from a first cervical vertebrae to a third cervical vertebrae of the patient.

10. The system of claim 1, wherein the first set of electrodes is configured to be implanted proximate to an eye of the patient, and the second set of electrodes is configured to be implanted within a region from a first cervical vertebrae to a third cervical vertebrae of the patient.

11. The system of claim 1, wherein the first set of electrodes is configured to be implanted within or between dermal or subcutaneous tissue on a chest of the patient, and the second set of electrodes is configured to be implanted within a region from a first cervical vertebrae fourth thoracic vertebrae of the patient.

12. The system of claim 1, wherein the second set of electrodes is configured to be implanted at least one of in an epidural space or proximal to a dorsal root entry zone of the patient.

13. A method of treating pain of a patient comprising:

delivering peripheral nerve field stimulation to a region of a body of the patient in which the patient experiences pain via a first set of one or more electrodes of a first implantable medical device, the first set of one or more electrodes implanted in the region; and

delivering spinal cord stimulation to the patient via a second set of one or more electrodes of a second implantable medical device, the second set of one or more electrodes implanted proximate to a spinal cord of the patient.

14. The method of claim 13, further comprising communicating between the first and second implantable medical devices to coordinate delivery of the peripheral nerve field stimulation and spinal cord stimulation.

15. The method of claim 13, wherein the first implantable medical device comprises a housing implantable within the region of the body in which the patient experiences pain, and the first set of electrodes comprises an array of electrodes located on the housing.

16. The method of claim 13, wherein the first implantable medical device is implanted within at least one of the intra-dermal, deep dermal, or subcutaneous layer of the region.

17. The method of claim 13, further comprising delivering the peripheral nerve field stimulation and the spinal cord stimulation simulation substantially simultaneously.

18. The method of claim 13, further comprising alternating delivery of the peripheral nerve field stimulation and the spinal cord stimulation.

19. The method of claim 13, wherein the first set of electrodes is implanted in an axial region of a back of the patient.

20. The method of claim 19, wherein the second set of electrodes is implanted within a region from a seventh thoracic vertebrae to a first lumbar vertebrae of the patient.

21. The method of claim 13, wherein the first set of electrodes is implanted proximate to a branch of a spinal nerve that originates in a region from a second cervical vertebrae to a third cervical vertebrae of the patient, and the second set of electrodes is implanted within a region from a first cervical vertebrae to the third cervical vertebrae of the patient.