Method and device for acquiring physiological data during tissue stimulation procedure

• US 9,399,132 B2
• Filed: 06/28/2010
• Issued: 07/26/2016
• Est. Priority Date: 06/30/2009
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Parramon, Jordi, Feldman, Emanuel, Shi, Jess Weiqian
• Primary Examiner(s): Flory, Christopher A
• Application Number:
  US12/825,187
• Publication Number:
  US 20100331916A1
• Time in Patent Office: 2,220 Days
• Field of Search: 607/2, 607/72, 607/116
• US Class Current: 1/1
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/3614 based on impedance measurement
• CPC Class Codes: A61N 1/36164 Sub-threshold or non-excitatory signals non-excitatory signals to the heart A61N1/3628
• CPC Class Codes: A61N 1/37235 Aspects of the external programmer

Abstract

A method and system of providing therapy to a patient implanted with an array of electrodes is provided. A train of electrical stimulation pulses is conveyed within a stimulation timing channel between a group of the electrodes to stimulate neural tissue, thereby providing continuous therapy to the patient. Electrical parameter is sensed within a sensing timing channel using at least one of the electrodes, wherein the first stimulation timing channel and sensing timing channel are coordinated, such that the electrical parameter is sensed during the conveyance of the pulse train within time slots that do not temporally overlap any active phase of the stimulation pulses.

Claims

1. A neurostimulation system, comprising:

analog output circuitry configured for conveying a train of electrical stimulation pulses within a stimulation timing channel between a selected group of an array of electrodes to stimulate neural tissue;

monitoring circuitry configured for sensing an electrical parameter within a sensing timing channel using at least one of the electrodes; and

control circuitry configured for coordinating the stimulation timing channel and the sensing timing channel, such that the electrical parameter is sensed during the conveyance of the pulse train within time slots that do not temporally overlap any active phase of the stimulation pulses.

2. The neurostimulation system of claim 1, wherein the analog output circuitry is further configured for conveying another train of electrical stimulation pulses within another stimulation timing channel between another group of the electrodes in a manner that provides further therapy to the patient, wherein the control circuitry is configured for coordinating the stimulation timing channels and sensing timing channel, such that the electrical parameter is sensed during the conveyance of the pulse trains within time slots that do not temporally overlap any active phase of the stimulation pulses.

3. The neurostimulation system of claim 2, wherein the control circuitry is further configured for coordinating the stimulation timing channels, such that the stimulation pulses within the respective pulse trains do not temporally overlap any active phase of each other.

4. The neurostimulation system of claim 2, further comprising a memory configured for storing different stimulation parameters for independently programming the stimulation timing channels.

5. The neurostimulation system of claim 1, wherein the analog output circuitry is configured for transmitting sub-threshold pulses within the sensing timing channel between another group of electrodes, and the monitoring circuitry is configured for sensing the electrical parameter in response to the transmission of the sub-threshold pulses.

6. The neurostimulation system of claim 1, wherein the electrical parameter is selected from the group consisting of an electrical impedance, a field potential, and an evoked action potential.

7. The neurostimulation system of claim 1, further comprising the array of electrodes.

8. The neurostimulation system of claim 1, wherein the control circuitry is configured for coordinating the stimulation timing channel and the sensing timing channel by providing a hold-off period after the active phase of the stimulation pulses, such that no electrical parameter is sensed during the hold-off period.

9. The neurostimulation system of claim 1, further comprising telemetry circuitry configured for wirelessly transmitting the sensed electrical parameter to an external programmer.

10. The neurostimulation system of claim 1, wherein the analog output circuitry is configured for conveying a continuous train of electrical stimulation pulses within the stimulation timing channel between the electrodes.

11. A method of providing therapy to a patient implanted with an array of electrodes using the neurostimulation system of claim 1, the method comprising:

conveying from the analog output circuitry a train of electrical stimulation pulses within a stimulation timing channel between a group of the electrodes to stimulate neural tissue, thereby providing therapy to the patient; and

sensing by the monitoring circuitry an electrical parameter within a sensing timing channel using at least one of the electrodes, wherein the first stimulation timing channel and sensing timing channel are coordinated by the control circuitry, such that the electrical parameter is sensed during the conveyance of the pulse train within time slots that do not temporally overlap any active phase of the stimulation pulses.

12. The method of claim 11, further comprising conveying from the analog output circuitry another train of electrical stimulation pulses within another stimulation timing channel between another group of the electrodes, thereby providing further therapy to the patient, wherein the stimulation timing channels and sensing timing channel are coordinated by the control circuitry, such that the electrical parameter is sensed during the conveyance of the pulse trains within time slots that do not temporally overlap any active phase of the stimulation pulses.

13. The method of claim 12, wherein the stimulation timing channels are coordinated by the control circuitry, such that the stimulation pulses within the respective pulse trains do not temporally overlap any active phase of each other.

14. The method of claim 12, further comprising independently programming the stimulation timing channels with different stimulation parameters.

15. The method of claim 11, further comprising transmitting from the analog output circuitry sub-threshold pulses within the sensing timing channel between another group of the electrodes, wherein the electrical parameter is sensed by the monitoring circuitry in response to the transmission of the sub-threshold pulses.

16. The method of claim 11, wherein the electrical parameter is selected from the group consisting of an electrical impedance, a field potential, and an evoked action potential.

17. The method of claim 11, wherein the neural tissue is spinal cord tissue.

18. The method of claim 11, further comprising implanting the array of electrodes within the patient.

19. The method of claim 11, wherein the coordination of the first stimulation timing channel and sensing timing channel comprising providing a hold-off period after the active phase of the stimulation pulses, such that no electrical parameter is sensed during the hold-off period.

20. The method of claim 11, wherein the conveyance of the train of electrical stimulation pulses within the stimulation timing channel between the electrodes provides continuous therapy to the patient.