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Biochip

  • US 9,400,278 B2
  • Filed: 06/17/2014
  • Issued: 07/26/2016
  • Est. Priority Date: 12/19/2002
  • Status: Active Grant
First Claim
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1. A biochip, comprising:

  • a flat carrier;

    an array of spots containing catcher molecules, each spot being assigned a microelectrode arrangement for detecting binding events between the catcher molecules and target molecules applied via an analyte solution, wherein the microelectrode arrangement is at least a two-pole system, the microelectrode arrangement being at least partially embedded in a hydrophilic reaction layer which is permeable to target molecules and in which immobilized catcher molecules are distributed three-dimensionally, wherein the catcher molecules are configured to cause the binding events, wherein the hydrophilic reaction layer has a thickness of between 2 and 10 μ

    m, and a sum of electrode width and electrode spacing is from 2 to 100 μ

    m, wherein the microelectrode arrangement is an interdigital electrode arrangement, and wherein the hydrophilic reaction layer covers the interdigital electrode arrangement.

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