Clot capture systems and associated methods

• US 9,402,707 B2
• Filed: 10/26/2012
• Issued: 08/02/2016
• Est. Priority Date: 07/22/2008
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Vale, David, Gilvarry, Michael, Razavi, Mahmood, O'Shaughnessy, John
• Primary Examiner(s): Yabut, Diane
• Application Number:
  US13/662,299
• Publication Number:
  US 20130144326A1
• Time in Patent Office: 1,376 Days
• Field of Search: 606/113, 606/127, 606/200
• US Class Current: 1/1
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0058 X-shaped

Abstract

A clot capture system for disengaging a clot from a vessel wall and removing the clot from the vessel. The system may include a clot capture device for placement on a distal side of a clot. The clot capture device may have a retracted delivery configuration and an expanded deployed configuration. The clot removal device may have a proximal support frame, and a distal fiber net. The support frame may have a retracted delivery configuration and an expanded deployed configuration. The proximal support frame in the expanded configuration may define a proximal inlet mouth for engaging a clot and a net for confining the clot. An elongate member may facilitate capture and/or withdrawal of a clot from a vessel.

Claims

1. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration, the device comprising:

an expandable clot retrieval portion having a plurality of struts forming a clot inlet mouth having a pair of opposed bifurcations at a periphery of a proximal end of the clot retrieval portion, wherein the clot inlet mouth includes a distal-most apex at a midpoint between the pair of opposed bifurcations;

an expandable portion located proximal the clot retrieval portion, the expandable portion having a plurality of struts and a proximally tapering portion at a proximal end of the expandable portion;

a clot receiving space between the clot retrieval portion and the expandable portion; and

a longitudinally-extending member extending through the clot receiving space and coupled to the clot retrieval portion, wherein a central axis of the longitudinally-extending member is located along a central axis of both the clot retrieval portion and the expandable portion;

wherein two distal struts extend distally from each bifurcation of the pair of opposed bifurcations.

2. The clot removal device of claim 1, wherein the clot retrieval portion includes a distally tapering distal end portion.

3. The clot removal device of claim 2, wherein the plurality of struts of the expandable portion includes a plurality of struts formed by a distal end portion of a tubular member, the plurality of struts formed by the distal end portion of the tubular member defining openings through the expandable portion between the plurality of struts formed by the distal end portion of the tubular member.

4. The clot removal device of claim 1, wherein the bifurcations include a single strut extending proximally from a bifurcation point of the bifurcations.

5. The clot removal device of claim 1, including only two struts extending proximally from the clot inlet mouth.

6. The clot removal device of claim 1, wherein the longitudinally-extending member is a tubular member.

7. The clot removal device of claim 6, wherein the tubular longitudinally-extending member is movable relative to the proximal end of the clot retrieval portion.

8. The clot removal device of claim 7, wherein the tubular longitudinally-extending member is coupled to the clot retrieval portion at a distal end of the clot retrieval portion.

9. The clot removal device of claim 1, wherein a distal-most end of a first strut of the two distal struts extending distally from a first bifurcation point is directly joined with a distal-most end of a first strut of the two distal struts extending distally from a second bifurcation point, wherein the joined struts form a distally extending portion of the clot inlet mouth.

10. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration, the device comprising:

an expandable clot retrieval portion having;

a plurality of struts forming a clot inlet mouth, the clot inlet mouth including a pair of opposed bifurcations at a periphery of a proximal end of the clot retrieval portion, the bifurcations including branches extending distally from a bifurcation point, and a single strut extending proximally from the bifurcation points;

an expandable portion located proximal the clot retrieval portion, the expandable portion having a plurality of struts and a proximally tapering portion at a proximal end of the expandable portion; and

a clot receiving space between the clot retrieval portion and the expandable portion; and

a tubular longitudinally-extending member extending through the clot receiving space and coupled to the clot retrieval portion, wherein a central axis of the tubular longitudinally-extending member is located along a central axis of both the clot retrieval portion and the expandable portion, and the tubular longitudinally-extending member extends through the clot retrieval portion and is coupled to the clot retrieval portion at a distal end of the clot retrieval portion.

11. The clot removal device of claim 10, wherein the clot retrieval portion includes a distally tapering distal end portion.

12. The clot removal device of claim 11, wherein the struts of the expandable portion includes a plurality of struts formed by a distal end portion of a tubular member, the plurality of struts formed by the distal end portion of the tubular member defining openings through the expandable portion between the plurality of struts formed by the distal end portion of the tubular member.

13. The clot removal device of claim 10, wherein the clot inlet mouth of the clot retrieval portion includes a distal-most apex at a midpoint between the pair of opposed bifurcations.

14. The clot removal device of claim 10, wherein the clot inlet mouth includes only two bifurcations.

15. The clot removal device of claim 10, wherein the tubular longitudinally-extending member is movable relative to a proximal end of the clot retrieval portion.

16. The clot removal device of claim 10, wherein two distal branches extend distally from each bifurcation of the pair of opposed bifurcations, wherein a distal-most end of a first branch of the two distal branches extending distally from a first bifurcation point is directly joined with a distal-most end of a first branch of the two distal branches extending distally from a second bifurcation point, wherein the joined branches form a distally extending portion of the clot inlet mouth.

17. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery, the device comprising:

an expandable clot retrieval portion configured for deployment on a distal side of the clot, the clot retrieval portion having a plurality of struts forming a clot inlet mouth having a pair of opposed bifurcations at a periphery of a proximal end of the clot retrieval portion, wherein the clot inlet mouth includes a distal-most apex at a midpoint between the pair of opposed bifurcations, and wherein the clot retrieval portion includes a distally tapering distal end portion;

an expandable portion configured for deployment on a proximal side of the clot, the expandable portion having a plurality of struts and a proximally tapering portion at a proximal end of the expandable portion;

a clot receiving space between the clot retrieval portion and the expandable portion; and

a tubular longitudinally-extending member extending through the clot receiving space and coupled to the clot retrieval portion, wherein a central axis of the tubular longitudinally-extending member is located along a central axis of both the clot retrieval portion and the expandable portion, and the tubular longitudinally-extending member is coupled to the clot retrieval portion at a distal end of the clot retrieval portion;

wherein two distal struts extend distally from each bifurcation of the pair of opposed bifurcations.