Vascular devices and methods with distal protection

• US 9,402,708 B2
• Filed: 07/25/2013
• Issued: 08/02/2016
• Est. Priority Date: 07/25/2013
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Holloway, Ken
• Primary Examiner(s): Manahan, Todd E
• Assistant Examiner(s): Wei, Charles
• Application Number:
  US13/950,930
• Publication Number:
  US 20150032144A1
• Time in Patent Office: 1,104 Days
• Field of Search: 606/200, 623 111- 1143
• US Class Current: 1/1
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2230/0067 conical

Abstract

A device for treating a thrombus in a blood vessel includes a treatment section and a filter section. The treatment section can be generally cylindrical and comprise a plurality of individual filaments and individual cells, as well as a first edge and a second edge along a longitudinal axis of the device. A varying degree of overlap of the first edge and the second edge may be provided as the device transitions from a volume-reduced form to an expanded form. The filter section can be generally conical and accommodate the variable degree of overlap by providing a first section, distal to the treatment section, that has a variable degree of overlap with a non-continuous, interrupted surface. A second section, distal to the first section, has a continuous surface for providing effective filtering of debris and emboli dislodged from the thrombus during action upon the thrombus by the treatment section.

Claims

1. An expandable medical device, comprising:

a treatment section forming a cylindrical structure comprising a proximal end and a distal end;

wherein the cylindrical structure has a curled mesh structure such that a seam extends along a longitudinal axis of the expandable medical device;

wherein the treatment section is configured to be delivered in a volume-reduced form having overlapping edges; and

wherein the cylindrical structure is configured to at least partially uncurl to allow the treatment section to assume a volume-enlarged form;

a filter section attached to the treatment section, forming a conical structure, and comprising (i) a first section, distal to the treatment section, wherein the first section is configured to have overlapping first edges while the treatment section is in the volume-reduced form, and wherein the first edges are configured not to overlap while the treatment section is in the volume-enlarged form; and

(ii) a second section, distal to the first section, wherein the second section is configured to have overlapping second edges while the treatment section is in the volume-reduced form and while the treatment section is in the volume-enlarged form.

2. The expandable device of claim 1, wherein the first section has a circumferentially interrupted surface and the second section has a circumferentially continuous surface.

3. The expandable device of claim 1, further comprising a tapering section proximal to the treatment section.

4. The expandable device of claim 1, wherein the treatment section comprises a plurality of cells.

5. The expandable device of claim 1, wherein the filter section further comprises a plurality of fingers, each of the fingers extending proximally from a proximal edge of the first section, through a respective cell of the treatment section, and distally back to the first section, a portion of each finger being affixed to the first section.

6. The expandable device of claim 1, wherein the second section defines an opening at a distal end of the second section.

7. The expandable device of claim 1, wherein the treatment section, while in an expanded configuration, has a first cross-sectional dimension;

the first section, while in the expanded configuration, is configured to transition, along a longitudinal length of the first section, from the first cross-sectional dimension to a second cross-sectional dimension, less than the first cross-sectional dimension; and

the second section, while in the expanded configuration, transitions, along a longitudinal length of the second section, from the second cross-sectional dimension to a third cross-sectional dimension, less than the second cross-sectional dimension.

8. The expandable device of claim 1, wherein the treatment section, while in an expanded configuration, has a first cross-sectional dimension;

the first section, while in the expanded configuration, transitions, along a longitudinal length of the first section, from a second cross-sectional dimension, less than the first cross-sectional dimension, to a third cross-sectional dimension, less than the second cross-sectional dimension; and

the second section, while in the expanded configuration, transitions, along a longitudinal length of the second section, from the third cross-sectional dimension to a fourth cross-sectional dimension, less than the third cross-sectional dimension.

9. A self-expanding device for treating a thrombus, comprising:

a treatment section forming a generally cylindrical shape and comprising a seam along a longitudinal axis of the treatment section, the seam forming two edges extending generally longitudinally along the treatment section;

wherein the treatment section is configured to have a generally rolled, tubular configuration with the edges of the treatment section being overlapped in a volume-reduced rolled configuration such that the treatment section has multiple layers in at least one radial direction when the treatment section is in the volume-reduced rolled configuration;

wherein the treatment section is configured to self-expand from the volume-reduced rolled configuration to an expanded configuration; and

a filter section attached to the treatment section, forming a generally conical configuration, and comprising (i) a first section, distal to the treatment section, having a circumferentially continuous surface while the treatment section is in the volume-reduced rolled configuration and a circumferentially interrupted surface while the treatment section is in the expanded configuration and (ii) a second section, distal to the first section, having a circumferentially continuous surface while the treatment section is in the volume-reduced rolled configuration and while the treatment section is in the expanded configuration.

10. The self-expanding device of claim 9, wherein the treatment section comprises a plurality of mesh cells.

11. The self-expanding device of claim 9, wherein the filter section further comprises a plurality of fingers, each of the fingers extending proximally from a proximal edge of the first section, through a respective cell of the treatment section, and distally back to the first section, a portion of each finger being affixed to the first section.

12. The self-expanding device of claim 9, wherein the first section comprises a distal seam forming edges configured to overlap in the volume-reduced rolled configuration such that the first section has multiple layers in at least one radial direction.

13. The self-expanding device of claim 9, wherein the second section defines an opening at a distal end of the second section.

14. The self-expanding device of claim 9, wherein the treatment section, while in the expanded configuration, has a first cross-sectional dimension;

the first section, while in the expanded configuration, is configured to transition, along a longitudinal length of the first section, from the first cross-sectional dimension to a second cross-sectional dimension, less than the first cross-sectional dimension; and

the second section, while in the expanded configuration, transitions, along a longitudinal length of the second section, from the second cross-sectional dimension to a third cross-sectional dimension, less than the second cross-sectional dimension.

15. The self-expanding device of claim 9, wherein the treatment section, while in the expanded configuration, has a first cross-sectional dimension;

the first section, while in the expanded configuration, is configured to transition, along a longitudinal length of the first section, from a second cross-sectional dimension, less than the first cross-sectional dimension, to a third cross-sectional dimension, less than the second cross-sectional dimension; and

the second section, while in the expanded configuration, transitions, along a longitudinal length of the second section, from the third cross-sectional dimension to a fourth cross-sectional dimension, less than the third cross-sectional dimension.

16. The self-expanding device of claim 9, wherein the treatment section is configured to maintain the volume-reduced rolled configuration while within a catheter, and the treatment section is configured to self-expand from the volume-reduced rolled configuration to the expanded configuration when released from the catheter.

17. A thrombectomy device, comprising:

a treatment section forming a cylindrical structure comprising a proximal end, a distal end, and a plurality of cells;

wherein the cylindrical structure has a curled mesh structure such that a seam extends along a longitudinal axis of the thrombectomy device, wherein the treatment section is configured to at least partially uncurl from a volume-reduced form to a volume-enlarged form;

a filter section attached to the treatment section, the filter section forming a conical structure, the filter section comprising a main body, a proximal edge of the main body, and a plurality of fingers, at least a portion of the main body being of a preformed unsintered polymer material, each of the plurality of fingers wrapped through a respective one of the plurality of cells of the treatment section, at least a portion of each of the plurality of fingers being sintered to the main body, at least a portion of the filter section covering a portion of an inner surface of the treatment section, at least a portion of the filter section covering a portion of an outer surface of the treatment section, the main body comprising (i) a first section configured to have overlapping first edges while the treatment section is in the volume-reduced form, and wherein the first edges are configured not to overlap while the treatment section is in the volume-enlarged form; and

(ii) a second section, distal to the first section, wherein the second section is configured to have overlapping second edges while the treatment section is in the volume-reduced form and while the treatment section is in the volume-enlarged form.

18. The thrombectomy device of claim 17, wherein a portion of the inner surface of the treatment section remains uncovered between adjacent fingers.

19. The thrombectomy device of claim 17, wherein each of the plurality of fingers is spaced apart about a circumference of the proximal edge of the first section.

20. The thrombectomy device of claim 17, wherein the treatment section is configured to be delivered in the volume-reduced form having overlapping edges.