Expandable endoprostheses, systems, and methods for treating a bifurcated lumen

• US 9,402,754 B2
• Filed: 05/18/2010
• Issued: 08/02/2016
• Est. Priority Date: 05/18/2010
• Status: Active Grant

• Current Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Chan, Gregory W., Boylan, John F., Lee, Carol M., Kalvass, Laura M., Stamberg, Barbara E.
• Primary Examiner(s): LOUIS, RICHARD G
• Application Number:
  US12/782,399
• Publication Number:
  US 20110288622A1
• Time in Patent Office: 2,268 Days
• Field of Search: 623/1.11, 623/1.15, 623/1.35, 606/108
• US Class Current: 1/1
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

An endoprosthesis for treating a bifurcated lumen. The distal end of the endoprosthesis can include at least two wings and at least two troughs so the endoprosthesis can adequately scaffold the ostium of a bifurcated lumen by at least partially straddling the carina of the lumen bifurcation. The distal end of the endoprosthesis can also be configured to have increased expandability to help allow conformity to the anatomy of a bifurcated lumen.

Claims

1. An expandable endoprosthesis, comprising:

a tubular body having a distal end and a proximal end, a central longitudinal axis extending through the tubular body, a first plane and a second plane both parallel to the central longitudinal axis, the first plane and the second plane being orthogonal to each other, the distal end including at least two distally extending wing portions and at least two proximally extending recesses, the at least two distally extending wing portions being substantially symmetrical relative to both the first plane and the second plane, the at least two proximally extending recesses being substantially symmetrical relative to both the first plane and the second plane, the at least two distally extending wing portions and at least two proximally extending recesses being formed from at least one concentric ring having a plurality of alternating crests and valleys aligned in a wave pattern, a continuous inner surface of each at least two proximally extending recesses including a circumferentially extending transition recess intermediate a distal end of an adjacent wing portion and a proximal end of the recess,

wherein the at least two proximally extending recesses extend the length of at least two concentric rings of the tubular body such that when deployed proximate a bifurcated lumen the at least two proximally extending recesses are configured to straddle a carina portion of the bifurcated lumen without substantially contacting the carina, and

wherein expandability and flexibility of the expandable endoprosthesis increases from the proximal end to the distal end such that, when deployed proximate a bifurcated lumen, the distal end of the endoprosthesis may be expanded to a greater diameter than the proximal end and the at least two wing portions may extend into and along the lateral walls of the side branches of the bifurcated lumen.

2. The endoprosthesis as recited in claim 1, wherein the proximal end of the body is configured to expand from a contracted diameter to a first expanded diameter and at least a portion of the distal end of the body being configured to expand from the contracted diameter to a second expanded diameter that is larger than the first expanded diameter.

3. The endoprosthesis as recited in claim 1, wherein apices of the crests and valleys of the at least one concentric ring of the distal end have a semi-circular shape and are connected together by curved strut members.

4. The endoprosthesis as recited in claim 1, wherein the at least one concentric ring of the distal end comprises ten crests.

5. The endoprosthesis as recited in claim 1, wherein the at least one concentric ring of the distal end is secured to an adjacent concentric ring by a plurality of angled inter-connectors that extends between offset apices of valley and an adjacent crest.

21. The endoprosthesis as recited in claim 3, wherein a first closed cell is defined by an apex of a crest having a distal semi-circular shape, an apex of a valley having a proximal semi-circular shape, a first curved strut extending from a first end of the apex of the crest to a first end of the apex of the valley, a second curved strut extending from a second end of the apex of the crest to a second end of the apex of the valley, the first and second curved struts being convex relative to the crest and the valley.

22. The endoprosthesis as recited in claim 3, wherein one of the at least one concentric rings of the distal end forms a plurality of closed cells, and wherein the closed cells are walnut-shaped.

23. The endoprosthesis as recited in claim 22, wherein one of the at least one concentric rings of the proximal end forms a plurality of closed cells, and wherein the closed cells are not walnut-shaped.

24. The endoprosthesis as recited in claim 5, wherein at least two of the plurality of angled inter-connectors are non-parallel to each other.

25. The endoprosthesis as recited in claim 5, wherein at least two of the plurality of angled inter-connectors extend away from each other or extend toward each other.

26. The endoprosthesis as recited in claim 1, wherein a distal end of each wing portion has a generally convex configuration that extends to a concave portion of the inner surface.

27. The endoprosthesis as recited in claim 1, wherein the inner surface of the recess comprises a stepped configuration extending from the distal end to the proximal end.

6. An expandable endoprosthesis, comprising:

a tubular body having a distal end and a proximal end;

the proximal end of the body being configured to expand from a contracted diameter to a first expanded diameter; and

at least a portion of the distal end of the body being configured to expand from the contracted diameter to a second expanded diameter that is larger than the first expanded diameter;

wherein the distal end includes at least two distally extending wing portions formed from a web structure having a plurality of alternating crests and valleys and at least two recessed portions extending proximately into the distal end of the body between the at least two distally extending wing portions such that the distal end includes alternating wing portions and recessed portions, a continuous inner surface of each at least two proximally extending recesses including a circumferentially extending transition recess intermediate a distal end of an adjacent wing portion and a proximal end of the recess, and

wherein the distal end is configured in size and shape such that when deployed proximate a bifurcated lumen the at least two wing portions extend into and along the lateral walls of the side branches of the bifurcated lumen substantially without contacting a central wall portion of the bifurcated lumen;

wherein the distal end comprises a plurality of concentric rings having a plurality of alternating crests and valleys, the plurality of concentric rings being aligned in a wave pattern, the wave pattern defined by arranging the crests in a pattern of increasing and decreasing distal extent, such that crests having an increased distal extension form peaks of the wave pattern and crests having a decreased distal extension form troughs of the wave pattern;

wherein an inter-connector extends from each trough, adjacent to a distal-most peak forming one of the at least two distally extending wing portions of the distal concentric ring, and connecting the distal concentric ring with a longitudinally adjacent concentric ring of the plurality of concentric rings.

7. The endoprosthesis as recited in claim 6, wherein the two or more recessed portions and the two or more wing portions are sized and shaped to allow the distal end of the tubular body to straddle a carina of a bifurcated lumen substantially without contacting the carina.

8. The endoprosthesis as recited in claim 6, wherein the alternating wing portions and recessed portions are defined at least in part by at least one concentric ring, the at least one concentric ring including a plurality of alternating crests and valleys.

9. The endoprosthesis as recited in claim 8, wherein the at least one concentric ring is aligned in a wave pattern such that the peaks of the wave pattern define the at least two wing portions and the troughs of the wave pattern define the at least two recessed portions.

10. The endoprosthesis as recited in claim 6, wherein the proximal end of the tubular body is formed from a web structure including a plurality of diamond-shaped cells and the distal end of the tubular body is formed from a web structure including a plurality of rounded cells, wherein a first rounded cell is defined by an apex of a crest having a distal semi-circular shape, an apex of a valley having a proximal semi-circular shape, a first curved strut extending from a first end of the apex of the crest to a first end of the apex of the valley, a second curved strut extending from a second end of the apex of the crest to a second end of the apex of the valley, the first and second curved struts being convex relative to the crest and the valley.

11. An expandable, intraluminal endoprosthesis, comprising:

a tubular body having a length, proximal and distal ends, and a lumen extending therebetween;

at least two wing portions extending distally from the distal end of the tubular body, the at least two wing portions including a web structure having plurality of alternating crests and valleys; and

at least two recessed portions extending proximately into the distal end of the tubular body, wherein the at least two recessed portions extend proximally at least one quarter of the length of the tubular body;

wherein the distal end is configured in size and shape such that when deployed proximate a bifurcated lumen the at least two recessed portions straddle the carina substantially without contacting the carina of the bifurcated lumen and the at least two wing portions extend into and along the lateral walls of the side branches of the bifurcated lumen substantially without contacting a central wall portion of the bifurcated lumen;

wherein the distal end of the tubular body is formed from a web structure including a plurality of rounded cells, wherein a first rounded cell is defined by an apex of a crest having a distal semi-circular shape, an apex of a valley having a proximal semi-circular shape, a first curved strut extending from a first end of the apex of the crest to a first end of the apex of the valley, a second curved strut extending from a second end of the apex of the crest to a second end of the apex of the valley, the first and second curved struts being convex relative to the crest and the valley, the plurality of first and second curved struts forming a plurality of recesses along an inner surface of the at least two recessed portions.

12. The endoprosthesis as recited in claim 11, wherein the tubular body comprises a web pattern that includes a first web pattern and at least a second web pattern, wherein the web pattern changes from the first web pattern to the at least second web pattern along the length of the tubular body to correspond with the anatomy of a bifurcated lumen.

13. The endoprosthesis as recited in claim 12, wherein the tubular body comprises:

a proximal portion with a web pattern configured to uniformly expand from a contracted diameter to a first expanded diameter; and

a distal portion with a web pattern configured to expand from the contracted diameter to a second expanded diameter larger than the first expanded diameter.

14. The endoprosthesis as recited in claim 13, wherein the distal portion comprises a plurality of concentric rings having a plurality of alternating crests and valleys, the plurality of concentric rings being aligned in a wave pattern, the wave pattern defined by arranging the crests in a pattern of increasing and decreasing distal extent, such that crests having an increased distal extension form peaks of the wave pattern and crests having a decreased distal extension form troughs of the wave pattern.

15. The endoprosthesis as recited in claim 13, further comprising a central portion with a web pattern differing from the web patterns of the proximal portion and the distal portion.

16. An expandable endoprosthesis for treating a bifurcated lumen, comprising:

a first set of concentric rings including a plurality of alternating crests and valleys defining a proximal end of a tubular body, wherein at least one crest or valley of each concentric ring of the first set of concentric rings is directly joined to a crest or valley of an adjacent concentric ring of the first set of concentric rings;

a second set of concentric rings including a plurality of alternating crests and valleys defining a distal end of the tubular body, wherein at least one crest or valley of each concentric ring of the second set of concentric rings is indirectly joined to a crest or valley of an adjacent concentric ring of the second set of concentric rings by a plurality of angled inter-connecter elements, wherein at least two of the plurality of angled inter-connectors are non-parallel to each other such that the at least two of the plurality of angled inter-connectors extend away from each other or extend toward each other, two of the plurality of angled inter-connector elements extending from each valley adjacent a distal-most crest of a distal-most concentric ring of the second set of concentric rings; and

wherein the distal end of the tubular body includes at least two distally extending wing portions formed by the plurality of alternating crests and valleys of the second set of concentric rings and at least two recessed portions extending proximally the length of at least two concentric rings of the tubular body, a continuous inner surface of each at least two proximally extending recesses including a circumferentially extending transition recess intermediate a distal end of an adjacent wing portion and a proximal end of the recess, and

wherein the distal end is configured in size and shape such that when deployed proximate a bifurcated lumen the at least two recessed portions straddle the carina substantially without contacting the carina of the bifurcated lumen and the at least two wing portions extend into and along the lateral walls of the side branches of the bifurcated lumen substantially without contacting a central wall portion of the bifurcated lumen, and

wherein the first set of concentric rings provides a first expandability and flexibility and the second set of concentric rings providing a second expandability such that the expandability and flexibility of the expandable endoprosthesis increases from the proximal end to the distal end.

17. The endoprosthesis as recited in claim 16, wherein the distal end includes alternating wing portions and recessed portions.

18. The endoprosthesis as recited in claim 16, wherein the one or more inter-connector elements is angled and secures an apex of a crest of one concentric ring to an apex of a valley of an adjacent concentric ring.

19. The endoprosthesis as recited in claim 16, wherein the distal most concentric ring of the second set of concentric rings includes ten crests.

20. The endoprosthesis as recited in claim 16, wherein the second set of concentric rings are aligned in a wave pattern such that the peaks of the wave pattern at least partially define the at least two wing portions and the troughs of the wave pattern define at least two recessed portions extending proximately into the distal end of the tubular body.