Detecting conditions associated with medical device operations using matched filters

• US 9,402,949 B2
• Filed: 08/13/2013
• Issued: 08/02/2016
• Est. Priority Date: 08/13/2013
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Tieck, R. Marie, Alderete, Juan M. Jr., Haller, Matthew I.
• Primary Examiner(s): STILES, AMBER R.
• Application Number:
  US13/966,183
• Publication Number:
  US 20150051573A1
• Time in Patent Office: 1,085 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/16863 Occlusion detection
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066

Abstract

Apparatus are provided for infusion devices and related operating methods. An exemplary device includes a sensing arrangement to provide an output indicative of a characteristic that is influenced by operation of the device, and a control module that is coupled to the sensing arrangement to apply a matched filter corresponding to a condition associated with the operation of the device to the output of the sensing arrangement and detect that condition based on the filtered output. In one example, the device includes a motor coupled to a plunger of a reservoir and operable to displace the plunger, wherein the characteristic is a force opposing displacement of the plunger and the control module detects an occlusion condition in a fluid path from the reservoir based on filtered force measurements.

Claims

1. A fluid infusion device comprising:

a motor operable to displace a plunger of a reservoir;

a sensing arrangement to provide an output indicative of a characteristic influenced by displacement of the plunger; and

a control module coupled to the sensing arrangement to;

identify a current physical delivery configuration for the fluid infusion device;

identify a current delivery mode for the fluid infusion device;

select a matched filter associated with the current delivery mode and the current physical delivery configuration, the matched filter corresponding to a condition;

correlate the output of the sensing arrangement to an analysis domain variable associated with the matched filter to produce correlated output values;

apply the matched filter to the correlated output values by calculating a weighted sum of the respective values of the correlated output values using filter coefficient values of the matched filter as weighting factors for the respective correlated output values, resulting in a filtered output; and

detect the condition based on the filtered output.

2. The fluid infusion device of claim 1, the condition comprising an occlusion condition in a fluid path from the reservoir, wherein the sensing arrangement comprises a force sensing arrangement providing the output indicative of a force opposing the displacement of the plunger.

3. The fluid infusion device of claim 1, the condition comprising a leakage condition, wherein the sensing arrangement comprises a volume sensing arrangement providing the output indicative of a remaining volume of fluid in the reservoir.

4. A device comprising:

a motor coupled to a plunger of a reservoir, the motor being operable to displace the plunger;

a sensing arrangement to provide an output indicative of a characteristic influenced by operation of the motor; and

a control module coupled to the sensing arrangement to;

identify a current physical delivery configuration for the device;

identify a current delivery mode for the device;

select a matched filter associated with the current delivery mode and the current physical delivery configuration;

correlate the output of the sensing arrangement to an analysis domain variable associated with the matched filter corresponding to a condition associated with the operation of the device by interpolating the output of the sensing arrangement to obtain correlated output values comprising estimated output values for intermediate values of the analysis domain variable between analysis domain variable values corresponding to the output;

apply the matched filter by calculating a weighted sum of the respective correlated output values using filter coefficient values of the matched filter as weighting factors for the respective correlated output values, resulting in a filtered output; and

detect the condition based on the filtered output.

5. The device of claim 4, wherein:

the filter coefficient values comprise a first set of values corresponding to an expected output from the sensing arrangement in response to the condition and a second set of values to cancel the first set of values such that an integral of the matched filter is equal to zero; and

the first set of values and the second set of values are scaled so that the second set of values comprise integer values equal to a power of two.

6. The device of claim 4, wherein:

the analysis domain variable comprises a number of motor steps;

the output comprising force measurements obtained before and after an operation of the motor; and

the control module is configured to obtain the correlated output by interpolating the force measurements to estimate force measurement values for each incremental motor step during the operation of the motor.

7. A device comprising:

a motor coupled to a plunger of a reservoir, the motor being operable to displace the plunger;

a sensing arrangement to provide an output indicative of a characteristic influenced by operation of the motor; and

a control module coupled to the sensing arrangement to;

identify a current physical delivery configuration for the device;

identify a current delivery mode for the device;

select a matched filter associated with the current delivery mode and the current physical delivery configuration;

correlate the output of the sensing arrangement to an analysis domain variable associated with the matched filter corresponding to a condition, resulting in a correlated output

apply the matched filter by calculating a weighted sum of respective values of the correlated output using filter coefficient values of the matched filter as weighting factors for the respective values, resulting in a filtered output; and

detect the condition based on the filtered output.

8. The device of claim 7, wherein:

the filter coefficient values comprise a first set of values corresponding to an expected output from the sensing arrangement in response to the condition and a second set of values to cancel the first set of values such that an integral of the matched filter is equal to zero; and

the first set of values and the second set of values are scaled so that the second set of values comprise integer values equal to a power of two.

9. The device of claim 7, wherein:

the characteristic comprises a force opposing displacement of the plunger.

10. The device of claim 9, wherein the condition comprises an occlusion condition in a fluid path from the reservoir.

11. The device of claim 10, wherein an impulse response of the matched filter corresponds to an expected output from the sensing arrangement in response to the occlusion condition.

12. The device of claim 9, further comprising a gear assembly to couple a rotor of the motor to a shaft of the plunger, wherein the sensing arrangement is integrated with the gear assembly.

13. The device of claim 7, wherein the control module identifying the current physical delivery configuration comprises one or more of identifying a type of infusion set coupled to the reservoir to provide a fluid path from the reservoir to a user, identifying a length of tubing of an infusion set coupled to the reservoir to provide the fluid path from the reservoir to the user, identifying a type of the reservoir, or identifying a volume of the reservoir.

14. The device of claim 7, wherein the current delivery mode comprises a basal delivery mode or a bolus delivery mode.

15. The device of claim 7, wherein the control module identifying the current delivery mode comprises the control module identifying a rate of delivery of fluid from the reservoir.

16. The device of claim 7, wherein the matched filter comprises a first set of values corresponding to an expected output from the sensing arrangement in response to the condition.

17. The device of claim 16, the expected output having a first slope, wherein the first set of values have a second slope substantially equal to a negative of the first slope.

18. The device of claim 16, wherein an integral of the matched filter is equal to zero.

19. The device of claim 16, wherein the matched filter further comprises a second set of values to cancel the first set of values such that an integral of the matched filter is equal to zero, the second set of values comprising integer values equal to a power of two.

20. The device of claim 7, wherein:

the output comprises a force measurement output indicative of a force opposing the displacement of the plunger from a force sensing arrangement;

the matched filter corresponds to an occlusion condition the filtered output comprising a filtered force measurement; and

the condition comprises the occlusion condition detected when a magnitude of the filtered force measurement is greater than an occlusion force threshold.

21. The device of claim 7, wherein:

the output comprises a volume measurement output indicative of a remaining volume of fluid in the reservoir from a volume sensing arrangement;

the matched filter corresponds to a leakage condition;

the filtered output comprises a filtered volume measurement; and

the condition comprises the leakage condition detected based on the filtered volume measurement.