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Integrated closed-loop medication delivery with error model and safety check

  • US 9,402,953 B2
  • Filed: 11/18/2013
  • Issued: 08/02/2016
  • Est. Priority Date: 03/31/2009
  • Status: Active Grant
First Claim
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1. An integrated system for the delivery of medication to a patient, the system comprising:

  • a controller programmed to receive a sensor glucose measurement signal, to provide a delivery control signal to a medication delivery device as a function of the received sensor glucose measurement signal in accordance with a control model and a glucose measurement error model, and to adjust a value of the delivery control signal in accordance with safety checks, wherein the safety checks;

    impose a maximum infusion rate related to a basal rate, the maximum infusion rate being dependent on a current sensor glucose level, time since a previous meal, and carbohydrate content of a meal; and

    cap the medication infusion to a pre-programmed basal rate in response to an inference of an occlusion of the medication delivery device.

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