RF electrodes on multiple flexible wires for renal nerve ablation

• US 9,408,661 B2
• Filed: 07/18/2011
• Issued: 08/09/2016
• Est. Priority Date: 07/30/2010
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Haverkost, Patrick A.
• Primary Examiner(s): Peffley, Michael
• Assistant Examiner(s): Zink, Amanda
• Application Number:
  US13/184,677
• Publication Number:
  US 20120029510A1
• Time in Patent Office: 1,849 Days
• Field of Search: 60 32- 48
• US Class Current: 1/1
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00214 Expandable means emitting energy, e.g. by elements carried thereon
• CPC Class Codes: A61B 2018/00226 extending from a surface, i.e. Blisters
• CPC Class Codes: A61B 2018/00232 having an irregular shape
• CPC Class Codes: A61B 2018/00267 having a basket shaped structure
• CPC Class Codes: A61B 2018/00434 Neural system
• CPC Class Codes: A61B 2018/00511 Kidney
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/1467 using more than two electrodes on a single probe
• CPC Class Codes: A61B 2018/1475 Electrodes retractable in or deployable from a housing

Abstract

A catheter includes a flexible shaft having a distal end dimensioned for deployment within a patient'"'"'s renal artery. A number of elongated resilient members are mounted along a longitudinal length of the distal end of the shaft, and are extensible radially from the shaft at regions defined between longitudinally spaced-apart engagement locations. One or more electrodes are mounted on each of the resilient members at the radially extensible regions. A number of conductors are electrically coupled to the electrodes and extend along the shaft of the catheter. The elongated resilient members are collapsible when encompassed within a lumen of an outer sheath and extensible radially outward from the shaft at the regions defined between the longitudinally spaced-apart engagement locations when the catheter and the resilient members are axially extended beyond the distal tip of the sheath. RF energy is delivered to the electrodes for ablating perivascular renal nerves.

Claims

1. An apparatus, comprising:

a sheath having a lumen and a length sufficient to access a patient'"'"'s renal artery relative to a percutaneous access location;

a catheter comprising a flexible shaft having a proximal end, a distal end, and a length, the length of the shaft sufficient to access a patient'"'"'s renal artery relative to the percutaneous access location, the shaft dimensioned for displacement within the lumen of the sheath and extendible beyond a distal tip of the sheath;

a plurality of elongated resilient members each mounted structurally independent of one another along a longitudinal length of the distal end of the shaft, the resilient members engaging the shaft at a plurality of longitudinally spaced-apart locations and extensible radially from the shaft at regions defined between the longitudinally spaced-apart engagement locations;

one or more electrodes mounted on each of the resilient members at the radially extensible regions; and

a plurality of conductors electrically coupled to the one or more electrodes and extending along the shaft of the catheter;

the elongated resilient members collapsible when encompassed within the lumen of the sheath and extensible radially outward from the shaft at the regions defined between the longitudinally spaced-apart engagement locations when the catheter and the resilient members are axially extended beyond the distal tip of the sheath, wherein a proximal end of the elongated resilient members is movable relative to the shaft, and wherein the electrodes are distributed about a perimeter of the catheter shaft to facilitate formation of a spiral lesion in a wall of the renal artery when the catheter and the resilient members are axially extended beyond the distal tip of the sheath.

2. The apparatus of claim 1, wherein the resilient members are arranged to form expandable curves or loops.

3. The apparatus of claim 1, wherein the resilient members are formed of a flexible electrically conductive material that facilitates flexing of the resilient members to accommodate variations in renal artery anatomy.

4. The apparatus of claim 1, wherein each of the electrodes comprises a tissue displacing tip.

5. The apparatus of claim 4, wherein the tissue displacing tips are configured to forcibly displace tissue of an inner wall of the renal artery relative to an outer wall of the renal artery to a prescribed depth, but not to pierce through at least the outer wall of the renal artery.

6. The apparatus of claim 1, wherein the electrodes are individually energizable to produce multiple discrete ablation regions of the renal artery.

7. The apparatus of claim 1, wherein the resilient members are formed of a material that produces elastic forces in the resilient members sufficient to cause self-expansion of the resilient members when the catheter and the resilient members are axially extended beyond the distal tip of the sheath.

8. The apparatus of claim 1, wherein the resilient members are formed of a flexible material that facilitates expansion and contraction of the resilient members in response to expansion and contraction control forces applied to the resilient members.

9. The apparatus of claim 1, wherein a portion of the resilient members between the electrodes is covered by an electrical insulator.