Pen-type injector

• US 9,408,979 B2
• Filed: 11/19/2015
• Issued: 08/09/2016
• Est. Priority Date: 03/03/2003
• Status: Expired due to Term

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Veasey, Robert Frederick, Perkins, Robert, Plumptre, David Aubrey
• Primary Examiner(s): MENDEZ, MANUEL A
• Application Number:
  US14/946,203
• Publication Number:
  US 20160074590A1
• Time in Patent Office: 264 Days
• Field of Search: 604208-211, 604/68, 128/DIG.12, 128/DIG.13
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/2407 from the rear
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31536 Blocking means to immobilize a selected dose, e.g. to administer equal doses
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/3156 using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
• CPC Class Codes: A61M 5/31563 interacting with a displaceable stop member
• CPC Class Codes: A61M 5/31565 Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31575 using scaling up or down transmissions, e.g. gearbox
• CPC Class Codes: A61M 5/31578 based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 : Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
• CPC Class Codes: A61M 5/32 : Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Claims

1. A drive mechanism for use in a drug delivery device comprising:

a housing having a longitudinal axis and comprising an inner surface with an insert that is rotationally and axially fixed relative to the housing;

a piston rod positioned and aligned with the longitudinal axis having a first thread on a first end that is engaged with the insert; and

a drive sleeve that extends about the piston rod and has internal and outer surfaces, where the internal surface is engaged with the piston rod;

wherein longitudinal axial movement of the drive sleeve causes the piston rod to rotate through the insert relative to the housing.

2. The drive mechanism of claim 1 where the rotation of the piston rod advances a piston in a cartridge.

3. The drive mechanism of claim 1 where the piston rod has a second thread on a second end.

4. The drive mechanism of claim 3 where the drive sleeve has an internal surface comprising a helical groove that engages the second thread of the piston rod.

5. The drive mechanism of claim 4 further comprising a dose dial sleeve having an outer surface having a helical thread with a lead, where the helical groove of the drive sleeve has a lead that is equal to the lead of the helical thread of the helical thread on the dose dial sleeve.

6. The drive mechanism of claim 5 where the first thread and second thread have opposing directions to prevent the piston rod from rotating when the dose dial sleeve is extended axially from the housing.

7. The drive mechanism of claim 3 where the first thread has a different lead than the second thread.

8. The drive mechanism of claim 3 where the second thread comprises a series of part threads.

9. The drive mechanism of claim 3 where the first thread of the piston rod is oppositely disposed to the second thread of the piston rod.

10. The drive mechanism of claim 3 where the piston rod further comprises a receiving recess at the second end that accepts a stem of a button.