Drug delivery device

• US 9,408,985 B2
• Filed: 03/28/2011
• Issued: 08/09/2016
• Est. Priority Date: 05/20/2010
• Status: Active Grant

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Cronenberg, Richard A., Vedrine, Lionel, Alchas, Paul
• Primary Examiner(s): Osinski, Bradley
• Application Number:
  US13/698,894
• Publication Number:
  US 20130110049A1
• Time in Patent Office: 1,961 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/1426 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

The subject invention provides a drug delivery device for injecting medicament which includes: a tubular reservoir; a stopper slidably disposed in the reservoir; a spring for moving the stopper in the reservoir; at least one needle, the needle having a distal end for insertion into a patient, and a lumen extending proximally from the distal end, the lumen being in direct or indirect communication with the reservoir; a needle driver for displacing the needle; and, an actuator. Activation of the actuator causes the spring to move the stopper and the needle driver to displace the needle. The needle moves relative to, and separately from, the reservoir with the needle being displaced. Advantageously, with the subject invention, a drug delivery device is provided wherein a needle is moved, relative to the reservoir, in being displaced for injection. This permits control of the needle displacement separate from the reservoir.

Claims

1. A drug delivery device for injecting medicament, said drug delivery device comprising:

a tubular reservoir for accommodating a medicament, said reservoir extending along a longitudinal axis;

a stopper slideably disposed in said reservoir;

a first spring for moving said stopper from a first position to a second position in said reservoir;

a needle, said needle having a distal end for insertion into a patient, and a lumen extending proximally from said distal end, said lumen being in direct or indirect communication with said reservoir, wherein, at least a portion of said lumen extending proximally from said distal end extends along a reference axis not coaxial with said longitudinal axis;

a second spring;

a needle driver for displacing said needle in a direction transverse to said longitudinal axis from a first state to a second state;

an actuator; and

a needle actuator driven by the second spring to displace in a direction parallel to the longitudinal axis, wherein during its displacement, the needle actuator interacts with the needle driver to cause said needle displacement

wherein activation of said actuator causes;

said first spring to move said stopper from said first position and toward said second position; and

said second spring to displace said needle actuator to cause said needle driver to displace said needle from said first state and toward said second state,

wherein, said needle moves relative to, and separately from, said reservoir with said needle being displaced from said first state and toward said second state.

2. A drug delivery device as in claim 1, further comprising a flow channel in communication with said lumen of said needle, said flow channel being selectively communicable with said reservoir,

wherein in an initial state, said flow channel not being in communication with said reservoir.

3. A drug delivery device as in claim 2, wherein activation of said actuator causes said channel to communicate with said reservoir.

4. A drug delivery device as in claim 2, further comprising an adjustable valve for permitting selective communication between said flow channel and said reservoir.

5. A drug delivery device as in claim 1 further comprising a second stopper disposed in said reservoir and spaced from said stopper.

6. A drug delivery device as in claim 5 further comprising a secondary needle having a lumen in communication with said flow path, said secondary needle having a proximal end, wherein, in an initial state, said proximal end of said secondary needle is spaced from, or partially embedded into, said second stopper, and, wherein, said second stopper being displaceable to be pierced therethrough by said secondary needle to permit said proximal end of said secondary needle to be in communication with said reservoir.

7. A drug delivery device as in claim 1 further comprising an adhesive for removably adherently securing the infuser to a patient.

8. A drug delivery device as in claim 1, wherein said needle driver includes a cantilevered arm, deformation of said cantilevered arm causing displacement of said needle from said first state and toward said second state.

9. A drug delivery device as in claim 8, wherein said needle driver further includes a spring member for causing deformation of said cantilevered arm.

10. A drug delivery device as in claim 1 further comprising an indicator for indicating that said stopper has moved to said second position.

11. A drug delivery device as in claim 1 further comprising a body in which said reservoir is accommodated, wherein, a window is formed in said body to permit viewing of at least a portion of said reservoir.

12. A drug delivery device as in claim 1 further comprising a body in which said reservoir is accommodated, wherein, in said first state, said distal end of said needle being within said body, and, wherein, in said second state, said distal end of said needle being exposed externally of said body.

13. A drug delivery device as in claim 1, wherein said reference axis is not parallel to said longitudinal axis.

14. A drug delivery device as in any of claim 1, wherein:

said needle driver includes a first interacting feature;

said needle actuator includes a second interacting feature; and

during said needle actuator displacement, said first and second interacting features interact to displace said needle from said first state to said second state.

15. A drug delivery device as in any of claim 14, wherein said first interacting feature includes a detent;

and

said second interacting feature includes a ramp surface.

16. A drug delivery device for injecting medicament, said drug delivery device comprising:

a tubular reservoir for accommodating a medicament, said reservoir extending along a longitudinal axis;

a stopper slideably disposed in said reservoir;

a spring for moving said stopper from a first position to a second position in said reservoir;

a needle, said needle having a distal end for insertion into a patient, and a lumen extending proximally from said distal end, said lumen being in direct or indirect communication with said reservoir, wherein, at least a portion of said lumen extending proximally from said distal end extends along a reference axis not coaxial with said longitudinal axis;

a needle driver for displacing said needle from a first state to a second state; and

,

an actuator, wherein activation of said actuator causes;

said spring to move said stopper from said first position and toward said second position; and

said needle driver to displace said needle from said first state and toward said second state,

wherein, said needle moves relative to, and separately from, said reservoir with said needle being displaced from said first state and toward said second state, and

wherein said needle driver includes a cantilevered arm and a spring member for causing deformation of said cantilevered arm, said deformation of said cantilevered arm causing displacement of said needle from said first state and toward said second state.

17. A drug delivery device for injecting medicament, said drug delivery device comprising:

a tubular reservoir for accommodating a medicament, said reservoir extending along a longitudinal axis;

a body accommodating said reservoir and having a substantially planar portion to which the longitudinal axis is parallel;

a stopper slideably disposed in said reservoir;

a first spring for moving said stopper from a first position to a second position in said reservoir;

a needle, said needle having a distal end for insertion into a patient, and a lumen extending proximally from said distal end, said lumen being in direct or indirect communication with said reservoir, wherein, at least a portion of said lumen extending proximally from said distal end extends along a reference axis not coaxial with said longitudinal axis;

a second spring;

a needle driver for displacing said needle in a direction transverse to said longitudinal axis from a first state to a second state;

a needle actuator driven by the second spring to displace in a direction parallel to the body'"'"'s planar portion, wherein during its displacement, the needle actuator interacts with the needle driver to cause said needle displacement; and

an actuator, wherein activation of said actuator causes;

said first spring to move said stopper from said first position and toward said second position; and

said second spring to displace said needle actuator to cause said needle driver to displace said needle from said first state toward said second state; and

wherein, said needle moves relative to, and separately from, said reservoir with said needle being displaced from said first state and toward said second state.

18. A drug delivery device as in claim 17, wherein:

said needle driver includes a first interacting feature;

said needle actuator includes a second interacting feature; and

during said needle actuator displacement, said first and second interacting features interact to displace said needle from said first state to said second state.

19. A drug delivery device as in claim 18, wherein said first interacting feature includes a detent;

and

said second interacting feature includes a ramp surface.