Cardiac rhythm management device with neural sensor
First Claim
1. An implantable medical device configured to provide a cardiac rhythm management (CRM) therapy to provide a physiologic system with a baseline response and configured to receive feedback from a transient nerve traffic response in a neural target within an autonomic nervous system (ANS), wherein perturbing the physiologic system causes the transient nerve traffic response before nerve traffic at the neural target returns to the baseline response, the device comprising:
- a CRM function module configured to apply the CRM therapy using an electrical signal to capture cardiac tissue, wherein the CRM therapy is configured to provide closed-loop cardiac stimulation to selected chambers of the heart in order to treat disorders of cardiac rhythm;
a neural function module configured to sense nerve traffic in the neural target within the ANS; and
a controller connected to the CRM function module and the neural function module, wherein the controller is configured to control the CRM therapy to provide closed-loop cardiac stimulation that causes the baseline response, implement a programmed protocol for receiving the feedback used to control the closed-loop cardiac stimulation, and adjust the CRM therapy using the feedback,wherein, in implementing the programmed protocol for receiving the feedback, the controller is configured to;
prepare to determine the transient nerve traffic response by perturbing the physiologic system from the baseline response to cause the transient nerve traffic response to the perturbed system, anddetermine the transient nerve traffic response to perturbing the physiologic system by monitoring nerve traffic at the neural target within a time period before nerve traffic at the neural target adapts to changes caused by perturbing the physiologic system and returns to the baseline response.
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Abstract
Various aspects of the present subject matter relate to a device. In various embodiments, the device comprises at least one port adapted to connect at least one lead, a CRM functions module connected to the port and adapted to provide at least one CRM function using the lead, a neural function module, and a controller connected to the CRM functions module and the neural function module. The at least one CRM function includes a function to provide an electrical signal to the lead to capture cardiac tissue. The neural function module includes a signal processing module connected to the port and adapted to receive and process a nerve traffic signal from the lead into a signal indicative of the nerve traffic. The controller is adapted to implement a CRM therapy based on the signal indicative of the nerve traffic. Other aspects are provided herein.
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Citations
12 Claims
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1. An implantable medical device configured to provide a cardiac rhythm management (CRM) therapy to provide a physiologic system with a baseline response and configured to receive feedback from a transient nerve traffic response in a neural target within an autonomic nervous system (ANS), wherein perturbing the physiologic system causes the transient nerve traffic response before nerve traffic at the neural target returns to the baseline response, the device comprising:
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a CRM function module configured to apply the CRM therapy using an electrical signal to capture cardiac tissue, wherein the CRM therapy is configured to provide closed-loop cardiac stimulation to selected chambers of the heart in order to treat disorders of cardiac rhythm; a neural function module configured to sense nerve traffic in the neural target within the ANS; and a controller connected to the CRM function module and the neural function module, wherein the controller is configured to control the CRM therapy to provide closed-loop cardiac stimulation that causes the baseline response, implement a programmed protocol for receiving the feedback used to control the closed-loop cardiac stimulation, and adjust the CRM therapy using the feedback, wherein, in implementing the programmed protocol for receiving the feedback, the controller is configured to; prepare to determine the transient nerve traffic response by perturbing the physiologic system from the baseline response to cause the transient nerve traffic response to the perturbed system, and determine the transient nerve traffic response to perturbing the physiologic system by monitoring nerve traffic at the neural target within a time period before nerve traffic at the neural target adapts to changes caused by perturbing the physiologic system and returns to the baseline response. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification