ECG sensing with noise filtering

• US 9,414,786 B1
• Filed: 09/20/2013
• Issued: 08/16/2016
• Est. Priority Date: 11/03/2009
• Status: Active Grant

• Current Assignee: VivaQuant LLC
• Original Assignee: VivaQuant LLC
• Inventors: Brockway, Marina, Brockway, Brian
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): KIMBALL, JEREMIAH T
• Application Number:
  US14/032,544
• Time in Patent Office: 1,061 Days
• Field of Search: 600/523, 600/300, 600/508, 600/509, 600/522
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/0026 characterised by the transmission medium
• CPC Class Codes: A61B 5/259 using conductive adhesive means, e.g. gels
• CPC Class Codes: A61B 5/276 Protection against electrode failure
• CPC Class Codes: A61B 5/30 Input circuits therefor
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/335 using integrated circuit memory devices
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7253 characterised by using transforms

Abstract

Various embodiments are directed to signal processing. In accordance with example embodiments, methods and apparatuses involve using at least two electrodes that sense an ECG signal. A denoising module is communicatively coupled to the at least two electrodes, and receives the ECG signal sensed by the sensing electrodes. The denoising module includes circuitry that conditions and digitizes the ECG signal, and a computing circuit that processes the digitized ECG signal to denoise the ECG signal. A communications circuit generates a communication including the denoised ECG signal for access by a remote device.

Claims

1. An apparatus comprising:

at least two electrodes configured and arranged to sense an ECG signal;

digitizing circuitry communicatively coupled to the at least two electrodes and configured and arranged to generate a digitized ECG signal from the ECG signal sensed via the electrodes; and

a computing circuit coupled to the digitizing circuitry and configured and arranged to generate a denoised ECG signal from the digitized ECG signal, the denoised ECG signal having, relative to the digitized ECG signal,

an improved signal-to-noise ratio of at least 15 dB as measured using the ANSI EC 57 standard, and

a quality of signal reconstruction greater than 95%.

2. The apparatus of claim 1, wherein the computing circuit is configured and arranged to generate the denoised ECG signal from a digitized ECG signal that has a signal-to-noise ratio of 0 dB and that includes a substantially noise-free ECG with white noise added as prescribed in the ANSI EC 57 standard.

3. The apparatus of claim 2, wherein the substantially noise-free ECG is an ECG having a signal-to-noise ratio of greater than 30 dB according to the ANSI EC 57 standard.

4. The apparatus of claim 1, wherein the computing circuit is configured and arranged to

decompose the digitized ECG signal from a first domain into subcomponents in a second domain that is different than the first domain, and

generate the denoised ECG signal by selecting and combining ones of the subcomponents based upon a time-based distribution of the subcomponents.

5. The apparatus of claim 4, wherein the computing circuit is configured and arranged to select and combine ones of the subcomponents by

identifying target subcomponents of the digitized ECG signal that are associated with a desired ECG signal based upon the time-based distribution of the subcomponents, and

reconstructing a denoised ECG signal in the first domain from at least two of the identified target subcomponents.

6. The apparatus of claim 1, wherein the computing circuit is a portable computer.

7. The apparatus of claim 1, wherein the computing circuit is a mobile telephone configured and arranged to receive the ECG signal sensed by the electrodes.

8. The apparatus of claim 1, further including an adhesive substrate configured and arranged to adhere to a patient, and wherein

the electrodes are coupled to the substrate and configured and arranged with the substrate to adhere to a patient and sense the ECG signal, and

the digitizing circuitry and computing circuit are coupled to the substrate between the electrodes.

9. The apparatus of claim 8, further including a wireless communication circuit configured and arranged to wirelessly communicate the denoised ECG signal with a remote transceiver.

10. The apparatus of claim 9, further including a battery coupled to the substrate and configured and arranged to power the digitizing circuitry, computing circuit and wireless communication circuit, the substrate being configured and arranged to support the battery while adhered to the patient.

11. The apparatus of claim 10, further including a housing that encloses the digitizing circuitry, computing circuit, wireless communication circuit and battery, the housing being connected to the substrate and the substrate being configured and arranged to support the housing while adhered to the patient, the housing being disposed between the electrodes.

12. The apparatus of claim 10, wherein the computing circuit and digitizing circuitry are configured and arranged to sample each ECG signal at 300 Hz or less, and the computing circuit is configured and arranged to reduce in-band noise of the digitized ECG signal using an average power consumption that is less than 500 micro-Watts per ECG signal.

13. The apparatus of claim 1, wherein the quality of signal reconstruction (QSR) is defined as

14. An apparatus comprising:

at least two electrodes configured and arranged to sense an ECG signal;

a wireless communication circuit configured and arranged to wirelessly communicate an ECG signal, corresponding to the sensed ECG signal, with a remote receiver;

digitizing circuitry configured and arranged to generate a digitized ECG signal from the ECG signal sensed via the electrodes; and

a computing circuit coupled to the digitizing circuitry and configured and arranged to generate a denoised ECG signal from the digitized ECG signal, the denoised ECG signal having, relative to the digitized ECG signal,

an improved signal-to-noise ratio of at least 15 dB as measured using the ANSI EC 57 standard, and

a quality of signal reconstruction greater than 95%.

15. The apparatus of claim 14,

wherein at least one of the electrodes and the wireless communication circuit are coupled to a common substrate that is configured and arranged with the electrodes to sense the ECG signal, and

further including a portable device including the digitizing circuitry, the computing circuit and a second wireless communication circuit configured and arranged to receive the wirelessly-communicated ECG signal, the digitizing circuitry being configured and arranged to generate the digitized ECG signal from the wirelessly-communicated ECG signal.

16. The apparatus of claim 15, wherein the wireless communication circuits are configured and arranged with at least one of a speaker and a microphone to communicate the ECG signal via sound waves.

17. The apparatus of claim 16, wherein the electrodes and the wireless communication circuit are integrated in a chassis configured and arranged to attach to the portable device and to generate sound waves, the portable device including microphone configured and arranged to receive the generated sound waves when attached to the chassis, and the second wireless communication circuit being configured and arranged with the microphone to receive the ECG signal communicated via the sound waves and to provide the received ECG signal to the digitizing circuitry.

18. An ECG device comprising:

an electrode assembly configured to sense heart-related signals upon contact with a user'"'"'s skin, and to convert the sensed heart-related signals to ECG electrical signals wherein the electrode assembly is positioned on an outer surface of a smartphone protective case; and

a converter assembly including an audio transmitter for outputting frequency modulated ultrasonic signals, the converter assembly integrated with, and electrically connected to the electrode assembly and configured to receive the ECG electrical signals generated by the electrode assembly and output ECG sound signals through the audio transmitter to a microphone in a computing device within range of the audio transmitter, wherein the converter assembly is further configured to output the ECG signals as an ultrasonic FM sound signal, wherein the audio transmitter is configured to output the ultrasonic FM sound signal to a microphone in a computing device within range of the audio transmitter, wherein the output from the audio transmitter is detectable by a microphone in a smartphone when the smartphone is positioned within the smartphone protective case;

digitizing circuitry configured and arranged to generate a digitized ECG signal based on the ECG electrical signals generated by the electrode assembly; and

a computing circuit coupled to the digitizing circuitry and configured and arranged to generate a denoised ECG signal from the digitized ECG signal, the denoised ECG signal having, relative to the digitized ECG signal,

an improved signal-to-noise ratio of at least 15 dB as measured using the ANSI EC 57 standard, and

a quality of signal reconstruction greater than 95%.

19. The ECG device of claim 18, wherein the digitizing circuitry is configured and arranged to receive the ECG electrical signals via the ultrasonic FM sound signal.

20. The ECG device of claim 18, wherein the converter assembly includes the digitizing circuitry and the computing circuit, and is configured and arranged to output the ECG sound signals based upon the denoised ECG signal.

21. An apparatus comprising:

at least two electrodes configured and arranged to sense an ECG signal;

a denoising module communicatively coupled to the at least two electrodes and configured and arranged to receive the ECG signal sensed by the electrodes, the denoising module including;

circuitry configured and arranged to condition and digitize the ECG signal, and

a computing circuit configured to process said digitized ECG signal to denoise the ECG signal, based upon a time-based distribution of subcomponents of the signal; and

a communications circuit configured and arranged to generate a wireless communication including the denoised ECG signal for access by a device remote from the communications circuit.