Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
First Claim
1. A method of inducing locomotor activity in a mammal, said method comprising administering non-invasive transcutaneous electrical spinal cord stimulation (tSCS) to said mammal at a frequency and intensity sufficient to elicit said locomotor activity, wherein said locomotor activity comprises step-like movements and the frequency of said step like movements does not depend on the frequency of the transdermal electrical stimulation.
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Abstract
This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.
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Citations
22 Claims
- 1. A method of inducing locomotor activity in a mammal, said method comprising administering non-invasive transcutaneous electrical spinal cord stimulation (tSCS) to said mammal at a frequency and intensity sufficient to elicit said locomotor activity, wherein said locomotor activity comprises step-like movements and the frequency of said step like movements does not depend on the frequency of the transdermal electrical stimulation.
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2. A method of inducing locomotor activity in a mammal, said method comprising administering non-invasive transcutaneous electrical spinal cord stimulation (tSCS) to said mammal at a frequency and intensity sufficient to elicit said locomotor activity, wherein said locomotor activity comprises step-like movements, wherein the hip, knee, and ankle joints are involved in said step-like movements.
Specification