Steerable ultrasound catheter

• US 9,421,024 B2
• Filed: 03/07/2014
• Issued: 08/23/2016
• Est. Priority Date: 08/26/2002
• Status: Active Grant

• Current Assignee: Flowcardia Inc. (Becton, Dickinson & Co)
• Original Assignee: Flowcardia Inc. (Becton, Dickinson & Co)
• Inventors: Nita, Henry, Sarge, Jeff
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US14/201,649
• Publication Number:
  US 20140188146A1
• Time in Patent Office: 900 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/22004 using mechanical vibrations, e.g. ultrasonic shock waves A61B17/225 takes precedence
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 17/320068 using mechanical vibrations, e.g. ultrasonic A61B17/22012 takes precedence; dental tooth drilling devices operated by vibration A61C3/03; removing intra-ocular material using mechanical vibrations A61F9/00745
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/22014 the ultrasound transducer being outside patient's body; with an ultrasound transmission member; with a wave guide; with a vibrated guide wire not applied in A61B17/22012
• CPC Class Codes: A61B 2017/308 with suction cups
• CPC Class Codes: A61B 2017/32007 with suction or vacuum means
• CPC Class Codes: A61B 2017/320071 with articulating means for working tip
• CPC Class Codes: A61M 25/0054 with regions for increasing flexibility

Abstract

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

Claims

1. An ultrasound catheter comprising:

a catheter body having a proximal portion, a distal portion, a distally narrowing taper, and at least one lumen, wherein the proximal portion is stiffer than the distal portion, and the distal portion is more flexible near a distal end of the catheter body than near the proximal portion of the catheter body;

an ultrasound transmission member extending longitudinally through the at least one lumen and having a proximal end, a distal end, and a distally narrowing taper;

a distal head coupled with the distal end of the ultrasound transmission member and disposed adjacent the distal end of the catheter body; and

at least one coupling member for coupling the ultrasound transmission member with a source of ultrasound energy, wherein

the ultrasound transmission member is more flexible near its distal end than near its proximal end and contacts a guidewire,

the distal portion of the catheter body and the ultrasound transmission member are sufficiently flexible to conform concomitantly with at least one bend in the guidewire extended through the at least one lumen,

the distally narrowing taper of the ultrasound transmission member extends distally beyond the distally narrowing taper of the catheter body.

2. An ultrasound catheter as in claim 1 wherein the distal portion of the catheter body and the ultrasound transmission member are sufficiently flexible to conform concomitantly to multiple bends in the guidewire.

3. An ultrasound catheter as in claim 2 wherein the distal portion of the catheter body and the ultrasound transmission member are sufficiently flexible to conform concomitantly to multiple bends in a blood vessel.

4. An ultrasound catheter as in claim 3 wherein the distal portion of the catheter body, the ultrasound transmission member and the guidewire may be passed together or sequentially through the multiple bends in the blood vessel while conforming concomitantly to the multiple bends.

5. An ultrasound catheter as in claim 1 wherein the at least one coupling member comprises a housing fixedly coupled with the proximal portion of the catheter body such that torque applied to the housing is transmitted along the catheter body to its distal portion.

6. An ultrasound catheter comprising:

an elongate flexible body having a proximal portion, a distal portion, a distally narrowing taper, and at least one lumen;

an ultrasound transmission member extending longitudinally through the at least one lumen and having a proximal end, a distal end, and a distally narrowing taper, the distally narrowing taper of the ultrasound transmission member extending distally beyond the distally narrowing taper of the elongate flexible body;

a guidewire tube disposed within the at least one lumen, the guidewire tube including at least one opening within the catheter body for allowing contact between a guidewire extending through the guidewire tube and the ultrasound transmission member; and

a distal head coupled with the distal end of the ultrasound transmission member and disposed adjacent the distal portion of the elongate flexible body.

7. An ultrasound catheter as in claim 6 wherein the proximal portion is stiffer than the distal portion.

8. An ultrasound catheter as in claim 7 further comprising at least one coupling member for coupling the ultrasound transmission member with a source of ultrasound energy.

9. An ultrasound catheter as in claim 8 wherein the distal portion is more flexible near a distal end of the elongate flexible body than near the proximal portion of the elongate flexible body.

10. An ultrasound catheter as in claim 9 wherein the ultrasound transmission member is more flexible near its distal end than near its proximal end.

11. An ultrasound catheter as in claim 10 wherein the distal portion of the elongate flexible body and the ultrasound transmission member are sufficiently flexible to conform concomitantly with at least one bend in the guidewire extended through the at least one lumen.

12. An ultrasound catheter as in claim 6 wherein the guidewire contacts the ultrasound transmission member nearer the distal portion of the elongate flexible body than the proximal portion of the elongate flexible body.

13. An ultrasound catheter as in claim 6 wherein the guidewire contacts the ultrasound transmission member nearer the proximal portion of the elongate flexible body than the distal portion of the catheter body.

14. An ultrasound catheter as in claim 6 wherein the guidewire contacts the ultrasound transmission member near the middle of the elongate flexible body.

15. An ultrasound catheter comprising:

a catheter body having a proximal portion, a distal portion, a distally narrowing taper, and at least one lumen;

an ultrasound transmission member extending longitudinally through the at least one lumen, contacting a guidewire, and having a proximal end, a distal end, and a distally narrowing taper, the distally narrowing taper of the ultrasound transmission member extending distally beyond the distally narrowing taper of the catheter body;

a distal head coupled with the distal end of the ultrasound transmission member and disposed adjacent the distal portion of the catheter body; and

a housing fixedly coupled with the proximal portion of the catheter body such that torque applied to the housing is transmitted along the catheter body to its distal portion.

16. An ultrasound catheter as in claim 15 wherein the distal portion of the catheter body and the ultrasound transmission member are sufficiently flexible to conform concomitantly to multiple bends in the guidewire.

17. An ultrasound catheter as in claim 16 wherein the distal portion of the catheter body and the ultrasound transmission member are sufficiently flexible to conform concomitantly to multiple bends in a blood vessel.

18. An ultrasound catheter as in claim 17 wherein the distal portion of the catheter body, the ultrasound transmission member and the guidewire may be passed together or sequentially through the multiple bends in the blood vessel while conforming concomitantly to the multiple bends.

19. An ultrasound catheter as in claim 18 wherein the ultrasound transmission member is more flexible near its distal end than near its proximal end.