Medical fluid cassettes and related systems and methods

• US 9,421,314 B2
• Filed: 07/15/2010
• Issued: 08/23/2016
• Est. Priority Date: 07/15/2009
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Inventors: Plahey, Kulwinder S., Jensen, Lynn, Jensen, Melvin D., Lindley, DeLoy, Fallon, Joseph Michael
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): LEE, BRANDY SCOTT
• Application Number:
  US12/836,740
• Publication Number:
  US 20110015610A1
• Time in Patent Office: 2,231 Days
• Field of Search: 604/500, 604/153, 604/28, 604/29
• US Class Current: 1/1
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/1524 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/267 used for pumping
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 2205/121 interface between cassette and base
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches

Abstract

A medical fluid delivery cassette configured for use with a medical fluid pumping system and related systems and methods. The medical fluid delivery cassette includes a base and a membrane that together define a fluid pump chamber. The medical fluid delivery cassette further includes a member configured to apply an outward force to an inner surface of the membrane.

Claims

1. A medical fluid pumping system, comprising:

a medical fluid pumping machine defining a cassette enclosure, the medical fluid pumping machine comprising a movable piston; and

a medical fluid cassette configured to be disposed within the cassette enclosure of the medical fluid pumping machine, the medical fluid cassette comprising

a base;

a membrane attached to the base, the membrane and a region of the base cooperating to define a fluid pump chamber, the cassette positionable within the cassette enclosure of the medical fluid pumping machine so that the membrane faces the piston and the membrane can be moved by the piston to decrease a volume of the fluid pump chamber; and

a member disposed within the fluid pump chamber and configured to apply an outward force to an inner surface of the membrane to increase the volume of the fluid pump chamber, the member comprising a first portion defining a recess configured to receive the piston.

2. The medical fluid pumping system of claim 1, wherein the region of the base that together with the membrane defines the fluid pump chamber is a recessed region of the base.

3. The medical fluid pumping system of claim 1, wherein the membrane together with the base further defines a flow pathway that leads from the fluid pump chamber to an inlet of the cassette and a flow pathway that leads from the fluid pump chamber to an outlet of the cassette.

4. The medical fluid pumping system of claim 1, wherein the member is attached to the base of the cassette.

5. The medical fluid pumping system of claim 1, wherein the member further comprises a second portion attached to the first portion, the second portion being moveable between an expanded position and a compressed position.

6. The medical fluid pumping system of claim 5, wherein the second portion is substantially cup-shaped in the expanded position and substantially planar in the compressed position.

7. The medical fluid pumping system of claim 1, wherein the member comprises a second resilient portion attached to the first portion, the second resilient portion configured to resiliently move between an expanded position and a compressed position, and the first portion configured to apply the outward force to the membrane when the second resilient portion is moved from the compressed position to the expanded position.

8. The medical fluid pumping system of claim 7, wherein the second resilient portion is substantially cup-shaped in the expanded position and substantially planar in the compressed position.

9. The medical fluid pumping system of claim 7, wherein the second resilient portion is a cup-shaped member having a sidewall that defines a plurality of circumferentially spaced apertures.

10. The medical fluid pumping system of claim 1, wherein the member disposed within the fluid pump chamber is a substantially planar spring.

11. The medical fluid pumping system of claim 10, wherein the substantially planar spring comprises a hub portion and a plurality of circumferentially spaced legs extending radially outward from the hub portion.

12. The medical fluid pumping system of claim 11, wherein the substantially planar spring further comprises feet extending from ends of the legs opposite the hub portion, and at least one of the feet has a width that is greater than a width of the leg to which the at least one of the feet is attached.

13. The medical fluid pumping system of claim 12, wherein the at least one of the feet has a curved configuration that substantially conforms to an adjacent surface of the base.

14. The medical fluid pumping system of claim 10, wherein the substantially planar spring is formed of one or more metals.

15. The medical fluid pumping system of claim 1, further comprising a resilient device positioned between the base of the cassette and the member disposed in the fluid pump chamber of the cassette, the resilient device configured to apply a force to the member.

16. The medical fluid pumping system of claim 15, wherein the resilient device is configured to self-expand after being compressed.

17. The medical fluid pumping system of claim 16, wherein the resilient device comprises an elastomeric member.

18. The medical fluid pumping system of claim 1, wherein the medical fluid pumping machine comprises a device configured to apply a force to the member disposed in the fluid pump chamber when the cassette is disposed in the cassette enclosure.

19. The medical fluid pumping system of claim 18, wherein the device is a resilient device configured to self-expand after being compressed.

20. The medical fluid pumping system of claim 18, wherein the device comprises a spring.

21. The medical fluid pumping system of claim 18, wherein the member has a stem portion disposed within an aperture of the base of the cassette.

22. The medical fluid pumping system of claim 21, wherein the device contacts the stem portion when the cassette is disposed in the cassette enclosure.

23. The medical fluid pumping system of claim 22, further comprising an o-ring surrounding the stem portion, the o-ring compressed between the stem portion and a portion of the base defining the aperture in which the stem portion is disposed.

24. The medical fluid pumping system of claim 21, wherein the cassette further comprises a seal secured to the base and disposed over the aperture defined by the base.

25. The medical fluid pumping system of claim 24, wherein the device contacts the seal when the cassette is disposed in the cassette enclosure, the seal being deformable such that the force can be transmitted from the device to the stem portion of the member via the seal.

26. The medical fluid pumping system of claim 1, wherein the member is configured to create a vacuum pressure of about 150 mbar to about 200 mbar within the fluid pump chamber by applying the outward force to the membrane.

27. The medical fluid pumping system of claim 1, wherein the member is configured to apply an outward force of about 20N to about 100N to the membrane.

28. The medical fluid pumping system of claim 1, wherein the medical fluid pumping machine comprises first and second movable pistons, and the membrane and regions of the base cooperate to define first and second fluid pump chambers, the cassette is positionable within the cassette enclosure of the medical fluid pumping machine so that the membrane faces the first and second pistons and the membrane can be moved by the first and second pistons to decrease volumes of the first and second fluid pump chambers, and first and second members are disposed within the first and second fluid pump chambers, respectively, and are configured to apply outward forces to the inner surface of the membrane to increase the volumes of the first and second fluid pump chambers.

29. The medical fluid pumping system of claim 28, wherein the medical fluid pumping machine comprises a rod having a first end region and a second end region, the rod configured such that the first end region can apply a force to the first member disposed in the first fluid chamber and the second end region can apply a force to the second member disposed in the second fluid chamber.

30. The medical fluid pumping system of claim 29, wherein the rod is pivotable about a central pivot point such that when the first end region applies the force to the first member causing the first member to apply the outward force to the membrane, the second end region moves away from the second member, and when the second end region applies the force to the second member causing the second member to apply the outward force to the membrane, the first end region moves away from the first member.

31. The medical fluid pumping system of claim 1, wherein the medical fluid pumping system is a dialysis system.

32. A medical fluid cassette, comprising:

a base;

a membrane attached to the base, the membrane and a region of the base cooperating to define a fluid pump chamber; and

a member disposed within the fluid pump chamber and configured to apply an outward force to an inner surface of the membrane to increase a volume of the fluid pump chamber, the member comprising a first portion defining a recess configured to receive a piston of a medical fluid pumping machine.

33. The medical fluid cassette of claim 32, wherein the region of the base that together with the membrane defines the fluid pump chamber is a recessed region of the base.

34. The medical fluid cassette of claim 32, wherein the membrane together with the base further defines a flow pathway that leads from the fluid pump chamber to an inlet of the cassette and a flow pathway that leads from the fluid pump chamber to an outlet of the cassette.

35. The medical fluid cassette of claim 32, wherein the member further comprises a second portion attached to the first portion, the second portion being moveable between an expanded position and a compressed position.

36. The medical fluid cassette of claim 35, wherein the second portion is substantially cup-shaped in the expanded position and substantially planar in the compressed position.

37. The medical fluid cassette of claim 32, wherein the member comprises a second resilient portion attached to the first portion, the second resilient portion configured to resiliently move between an expanded position and a compressed position, and the first portion configured to apply the outward force to the membrane when the second resilient portion is moved from the compressed position to the expanded position.

38. The medical fluid cassette of claim 32, further comprising a resilient device positioned between the base of the cassette and the member disposed in the fluid pump chamber of the cassette, the resilient device configured to apply a force to the member.

39. The medical fluid cassette of claim 38, wherein the resilient device is configured to self-expand after being compressed.

40. The medical fluid cassette of claim 32, wherein the member has a stem portion disposed within an aperture of the base of the cassette.

41. The medical fluid cassette of claim 40, further comprising an o-ring surrounding the stem portion, the o-ring compressed between the stem portion and a portion of the base defining the aperture in which the stem portion is disposed.

42. The medical fluid cassette of claim 40, wherein the cassette further comprises a seal secured to the base and disposed over the aperture defined by the base.