Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
First Claim
1. A method for treating a sex-hormone related condition of a subject in need thereof, comprising administering to the subject an effective amount of a compound having the following structure (I):
1 Assignment
0 Petitions
Accused Products
Abstract
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure:
wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.
38 Citations
19 Claims
- 1. A method for treating a sex-hormone related condition of a subject in need thereof, comprising administering to the subject an effective amount of a compound having the following structure (I):
Specification