Apparatus for determining at least one evaluation parameter of a blood sample

• US 9,429,562 B2
• Filed: 01/27/2014
• Issued: 08/30/2016
• Est. Priority Date: 03/24/2010
• Status: Active Grant

• Current Assignee: C. A. Casyso GmbH
• Original Assignee: C A Casyso AG
• Inventors: Schubert, Axel, Bels, Kevin
• Primary Examiner(s): SIEFKE, SAMUEL P
• Application Number:
  US14/165,323
• Publication Number:
  US 20140202231A1
• Time in Patent Office: 946 Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/02035 Determining blood viscosity
• CPC Class Codes: A61B 5/1427 Multiple blood sampling, e.g. at periodic or pre-established intervals
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/150251 Collection chamber divided into at least two compartments, e.g. for division of samples injection syringes having more than one chamber A61M5/19; syringes for injection of two or more media A61M5/2448, A61M5/284; sample preparation for further analysis A61B5/150755
• CPC Class Codes: A61B 5/153 Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
• CPC Class Codes: A61B 5/155 Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals devices loaded with multiple lancets simultaneously A61B5/15146
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/4821 Determining level or depth of anaesthesia A61B5/1106 takes precedence
• CPC Class Codes: G01N 33/49 Blood chemical methods for determining blood cell populations G01N33/5094; chemical analysis of blood groups or blood types G01N33/80
• CPC Class Codes: G01N 33/4905 Determining clotting time of blood by chemical methods G01N33/86, C12Q1/56
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

The present invention provides a method for determining at least one evaluation parameter of a blood sample, comprising the following steps: providing (S4) at least one blood gas parameter; providing (S5) at least one hemostasis parameter; and determining (S6 . . . S10″) the at least one evaluation parameter as a function of the blood gas parameter and/or the hemostasis parameter.

Claims

1. An apparatus for determining at least one evaluation parameter of a blood sample, comprising:

a blood gas analyzer configured to determine at least one blood gas parameter of the blood sample from the group of pH level and partial pressure of oxygen;

a thromboelastometer configured to determine at least one hemostasis parameter of the blood sample from the group of blood clotting time and blood clot formation time; and

an evaluation unit coupled to the thromboelastometer via a first data interface, coupled to the blood gas analyzer via a second data interface and configured to determine the at least one evaluation parameter as a function of the blood gas parameter and the hemostasis parameter, the evaluation unit comprising a processor;

wherein the processor is programmed to determine the at least one evaluation parameter of at least one blood sample by carrying out computer-executable instructions on in a non-transitory computer-readable medium for performing steps comprising;

providing the at least one blood gas parameter;

providing the at least one hemostasis parameter;

providing an interdependence parameter describing an interdependence between the blood gas parameter and the hemostasis parameter; and

determining the at least one evaluation parameter as a function of the blood gas parameter and the hemostasis parameter;

wherein determining the evaluation parameter comprises at least one of the following;

comparing the blood gas parameter with a blood gas parameter range and/or comparing the blood gas parameter with a blood gas parameter value;

wherein comparing the blood gas parameter with a blood gas parameter range and/or comparing the blood gas parameter with a blood gas parameter value is performed as a function of the interdependence parameter; and

wherein the interdependence parameter is provided by reading out a sensor, reading out a data input device and/or reading out a data storage.

2. The apparatus according to claim 1, further comprising a single cartridge for the blood sample.

3. The apparatus according to claim 1, wherein a temperature of the blood gas analyzer and/or the thromboelastometer is controlled as a function of a temperature parameter of the blood sample determined by a thermometer.