Valveless pharmaceutical infusion system

• US 9,433,728 B2
• Filed: 03/01/2013
• Issued: 09/06/2016
• Est. Priority Date: 03/01/2013
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Marsh, Charles
• Primary Examiner(s): Bosworth, Kami A
• Application Number:
  US13/783,213
• Publication Number:
  US 20140249349A1
• Time in Patent Office: 1,285 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1409 in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems needle sets A61M5/162
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14232 Roller pumps

Abstract

A valveless pharmaceutical infusion system for delivery of a pharmaceutical, such as a radiopharmaceutical, is described. The device may include two or more roller pumps, a fluid path set including a confidence, and a measuring device for measuring a property of the pharmaceutical. Methods for delivering a pharmaceutical, such as a radiopharmaceutical, using a valveless pharmaceutical infusion system are also describe.

Claims

1. A device for delivering a pharmaceutical, the device comprising:

two or more roller pumps comprising at least a first roller pump and a second roller pump; and

a fluid path set wherein a portion of the fluid path set is reversibly received by the two or more roller pumps, the fluid path set comprising;

a first tubing section fluidly connecting a pharmaceutical source to a confluence, wherein a flow of fluid through the first tubing section is controlled by the first roller pump;

a second tubing section fluidly connecting a source of medical fluid to the confluence, wherein a flow of fluid through the second tubing section is controlled by the second roller pump;

a third tubing section fluidly connecting the confluence to an exit port;

a fourth tubing section fluidly connecting the third tubing section or a portion thereof to a waste receptacle; and

a waste by-pass tubing section fluidly connecting an upstream portion of the fourth tubing section with a downstream portion of the fourth tubing section, wherein a flow of fluid through the waste by-pass tubing section is controlled by the second roller pump.

2. The device of claim 1, further comprising a delivery tubing section for delivering fluid to a patient, wherein the delivery tubing section is reversibly connected to the exit port.

3. The device of claim 1, wherein the two or more roller pumps further comprise a third roller pump configured to control a flow of fluid through the fourth tubing section.

4. The device of claim 3, further comprising a medical fluid by-pass tubing section fluidly connecting an upstream portion of the second tubing section to a downstream portion of the second tubing section.

5. The device of claim 4, wherein a flow of fluid through the medical fluid by-pass tubing section is controlled by the third roller pump.

6. The device of claim 5, wherein operating the third roller pump causes fluid to flow from the source of medical fluid through the medical fluid by-pass tubing section to the confluence, and into the third tubing section to the exit port.

7. The device of claim 4, wherein the medical fluid by-pass tubing section is fluidly connected to the upstream portion of the second tubing section by a first T-joint, and the medical fluid by-pass tubing section is fluidly connected to the downstream portion of the second tubing section by a second T-joint.

8. The device of claim 4, wherein the medical fluid by-pass tubing section is fluidly connected to the confluence.

9. The device of claim 1, wherein a first T-joint connects the third tubing section to the fourth tubing section.

10. The device of claim 1, wherein the waste by-pass tubing section is fluidly connected to the upstream portion of the fourth tubing section by a first T-joint, and the waste by-pass tubing section is fluidly connected to the downstream portion of the fourth tubing section by a second T-joint.

11. The device of claim 1, wherein fluid from the source of medical fluid can flow through the second tubing section, the confluence, the third tubing section, and into the waste receptacle through the waste by-pass tubing section.

12. The device of claim 1, further comprising an activity measuring device disposed between a first portion of the third tubing section and a second portion of the third tubing section.

13. The device of claim 12, wherein the activity measuring device comprises a measurement coil.

14. The device of claim 12, wherein the activity measuring device measures radioactivity.

15. The device of claim 1, further comprising one or more check valves.

16. The device of claim 1, wherein the confluence comprises one or more check valves.