System and method for accurately detecting cardiac events using multi-threshold processing

• US 9,433,793 B2
• Filed: 11/03/2008
• Issued: 09/06/2016
• Est. Priority Date: 11/03/2008
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Bharmi, Rupinder, Snell, Jeffery D.
• Primary Examiner(s): Kahelin, Michael
• Assistant Examiner(s): PHAM, MINH DUC GIA
• Application Number:
  US12/264,131
• Publication Number:
  US 20100114194A1
• Time in Patent Office: 2,864 Days
• Field of Search: 600/515, 600/509, 600/521, 607/9
• US Class Current: 1/1
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/346 Analysis of electrocardiograms
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control

Abstract

A system and method provide precise detection of the time of occurrence of a cardiac event of a heart. The method comprises the steps of sensing electrical activity of the heart to generate an electrogram of the heart and applying the electrogram to an event detector having a plurality of spaced apart thresholds. The thresholds are selected such that the electrogram has an amplitude for crossing at least one of the thresholds. The method further comprises determining a characteristic identifying feature of the electrogram at each threshold crossing of the electrogram, comparing the determined characteristic identifying features to an electrogram template, and identifying the time of occurrence of the cardiac event based upon the comparison.

Claims

1. A method of detecting the time of occurrence of a cardiac event of a heart, the method comprising:

sensing electrical activity of the heart to generate an electrogram of the heart;

applying the electrogram to an event detector having a plurality of thresholds, the electrogram having an amplitude for crossing a plurality of the thresholds;

determining a characteristic identifying feature of the electrogram at each of the plurality of threshold crossings of the electrogram;

comparing the determined characteristic identifying features to an electrogram template for each of the plurality of threshold crossings; and

identifying the time of occurrence of the cardiac event based upon the comparison.

2. The method of claim 1, wherein the characteristic identifying feature is electrogram slope.

3. The method of claim 1, wherein the characteristic identifying feature is electrogram amplitude.

4. The method of claim 1, wherein the characteristic identifying feature is time of threshold crossing.

5. The method of claim 1, wherein the step of identifying the time of occurrence of the cardiac event based upon the comparison comprises the steps of assigning a point on the electrogram template as a fiducial point, aligning the electrogram with the electrogram template and locating a point on the electrogram corresponding to the fiducial point on the electrogram template.

6. The method of claim 1, wherein the electrogram is a portion of a cardiac cycle.

7. The method of claim 6, further comprising the steps of defining a recording window and recording the electrogram during the recording window.

8. The method of claim 7, comprising the further step of initiating the recording window based upon real time detection of the cardiac event.

9. A system that detects the time of occurrence of a cardiac event of a heart, the system comprising:

a sensing circuit that senses electrical activity of the heart to generate an electrogram of the heart;

an event detector that acts upon the electrogram, the event detector having a plurality of thresholds, the electrogram having an amplitude for crossing a plurality of the thresholds; and

a processor that stores an electrogram template and determines a characteristic identifying feature of the electrogram at each of the plurality of threshold crossings of the electrogram, compares the determined characteristic identifying features to the electrogram template, and identifies the time of occurrence of the cardiac event based upon the comparison.

10. The system of claim 9, wherein the characteristic identifying feature is electrogram slope.

11. The system of claim 9, wherein the characteristic identifying feature is electrogram amplitude.

12. The system of claim 9, wherein the characteristic identifying feature is time of threshold crossing.

13. The system of claim 9, wherein the processer is programmed to assign a point on the electrogram template as a fiducial point, align the electrogram with the electrogram template based upon the characteristic identifying features and locate a point on the electrogram corresponding to the fiducial point on the electrogram template.

14. The system of claim 9, wherein the cardiac event is an R wave.

15. The system of claim 9, wherein the electrogram is a portion of a cardiac cycle.

16. The system of claim 15, wherein the processor is further programmed to define a recording window and to record the electrogram during the recording window.

17. The system of claim 16, wherein the processor is further programmed to initiate the recording window based upon a real time detection of the cardiac event.

18. In an implantable cardiac device, a system that detects the time of occurrence of a cardiac event of a heart comprising:

a sensing circuit that senses electrical activity of the heart to generate an electrogram of the heart;

an event detector that acts upon the electrogram, the event detector having a plurality of thresholds, the electrogram having an amplitude for crossing a plurality of the thresholds; and

a processor that stores an electrogram template and determines a characteristic identifying feature of the electrogram at each of the plurality of threshold crossings of the electrogram, compares the determined characteristic identifying features to the electrogram template, and identifies the time of occurrence of the cardiac event based upon the comparison.

19. The device of claim 18, wherein the characteristic identifying feature is electrogram slope.

20. The device of claim 18, wherein the characteristic identifying feature is electrogram amplitude.