Topical systems and methods for treating sexual dysfunction
First Claim
1. A method, comprising:
- administering, to a subject having or at risk of sexual dysfunction, a composition comprising an effective amount of MSH or an MSH agonist and molecular nitric oxide to treat or prevent the sexual dysfunction, and a carrier comprising phosphatidylcholine containing the molecular nitric oxide, wherein the composition is stable at room temperature.
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Accused Products
Abstract
The present invention generally relates to compositions and methods for topical or transdermal delivery, and treatment of sexual dysfunction. The compositions can be used in a variety of applications, including treating erectile dysfunction or sexual dysfunction. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid “stick,” etc., that can be rubbed or sprayed onto the skin, e.g., onto the penis, vulva, or other suitable portion of the skin. The composition can also be applied to a mucosal surface in some instances. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.
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Citations
39 Claims
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1. A method, comprising:
administering, to a subject having or at risk of sexual dysfunction, a composition comprising an effective amount of MSH or an MSH agonist and molecular nitric oxide to treat or prevent the sexual dysfunction, and a carrier comprising phosphatidylcholine containing the molecular nitric oxide, wherein the composition is stable at room temperature. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method, comprising:
administering, to a subject having or at risk of sexual dysfunction, a composition comprising an effective amount of MSH or an MSH agonist and molecular nitric oxide to treat or prevent the sexual dysfunction, and a carrier comprising phosphatidylcholine containing the molecular nitric oxide, wherein the first phase comprises no more than about 250 ppm of water by weight of the composition. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A method, comprising:
administering, to a subject having or at risk of sexual dysfunction, a composition comprising an effective amount of TRH and molecular nitric oxide to treat or prevent the sexual dysfunction, and a carrier comprising phosphatidylcholine containing the molecular nitric oxide, wherein the first phase comprises no more than about 250 ppm of water by weight of the composition. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
Specification