Hemodialysis and peritoneal dialysis systems having electrodialysis and electrodeionization capabilities

• US 9,440,016 B2
• Filed: 04/13/2015
• Issued: 09/13/2016
• Est. Priority Date: 03/06/2009
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Lin, Rongsheng, Ding, Yuanpang Samuel, White, James M., Chen, Ye, Lo, Ying-Cheng, Miller, Joshua, Rohde, Justin
• Primary Examiner(s): Kim, John
• Application Number:
  US14/684,675
• Publication Number:
  US 20150209500A1
• Time in Patent Office: 519 Days
• US Class Current: 1/1
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1674 using UV radiation sources for sterilising the dialysate
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: B01D 61/243 Dialysis
• CPC Class Codes: B01D 61/422 Electrodialysis
• CPC Class Codes: B01D 61/44 Ion-selective electrodialysis
• CPC Class Codes: B01D 61/58 Multistep processes

Abstract

Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodialysis and electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source, an ED/EDI unit. The carbon source, urease source, and/or the ED/EDI unit can be in the form of removable cartridges.

Claims

1. A method of performing hemodialysis comprising:

passing dialysis fluid from a dialyzer through, in any order, a carbon source, a urease source, and a combination unit comprising an electrodialysis (“

ED”

) component and an electrodeionization (“

EDI”

) component to produce a cleaned dialysis fluid, wherein the ED component and the EDI component are separate, and wherein the dialysis fluid is passed within the combination unit via a fluid path from the ED component to the separate EDI component; and

returning the cleaned dialysis fluid to the dialyzer.

2. The method of claim 1, which includes passing the dialysis fluid through an ion exchange unit before returning the cleaned dialysis fluid to the dialyzer.

3. The method of claim 1, which includes adding at least one dialysis fluid concentrate to the dialysis fluid before returning the cleaned dialysis fluid to the dialyzer.

4. The method of claim 1, which includes draining a portion of the dialysis fluid that is passed through at least one of the ED and EDI components.

5. The method of claim 1, which includes recirculating a portion of the dialysis fluid that is passed through at least one of the ED and EDI components.

6. The method of claim 1, which includes adding at least one of sterile/injectable or tap water to the dialysis fluid.

7. The method of claim 1, which includes filtering the dialysis fluid before returning the cleaned dialysis fluid to the dialyzer.

8. A method of performing peritoneal dialysis comprising:

recirculating dialysis fluid removed from a patient or dialyzer through, in any order, a carbon source, a urease source, and a combination unit comprising an electrodialysis (“

ED”

) component and an electrodeionization (“

EDI”

) component to produce a cleaned dialysis fluid, wherein the ED component and the EDI component are separate, and wherein the dialysis fluid is passed within the combination unit via a fluid path from the ED component to the separate EDI component; and

returning the cleaned dialysis fluid to the patient or dialyzer.

9. The method of claim 8, which includes passing the dialysis fluid through an ion exchange unit before returning the cleaned dialysis fluid to the patient.

10. The method of claim 8, which includes adding at least one dialysis fluid concentrate to the dialysis fluid before returning the cleaned dialysis fluid to the patient.