Neural stimulation modulation based on monitored cardiovascular parameter
First Claim
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1. A method, comprising:
- delivering vagus nerve stimulation in a recurring succession of stimulation cycles, each cycle including a stimulation on portion and a stimulation off portion, wherein a burst of pulses is delivered during the stimulation on portion and no stimulation is delivered during the stimulation off portion, wherein a duty cycle of the stimulation cycles represents a ratio of a duration of the stimulation on portion to a cycle duration;
sensing a physiological parameter selected from a group of parameters consisting of;
heart rate, blood pressure and respiration; and
adjusting the duty cycle of the stimulation cycles based on the sensed physiological parameter.
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Abstract
An aspect relates to a system for providing baroreflex stimulation. An embodiment of the system comprises a heart rate monitor to sense a heart rate and provide a signal indicative of the heart rate, and a baroreflex stimulator. The stimulator includes a pulse generator to intermittently generate a stimulation signal to provide baroreflex stimulation for a baroreflex therapy, and further includes a modulator to adjust the stimulation signal based on the signal indicative of the heart rate such that the stimulation signal provides a desired baroreflex stimulation corresponding to a desired heart rate.
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Citations
20 Claims
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1. A method, comprising:
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delivering vagus nerve stimulation in a recurring succession of stimulation cycles, each cycle including a stimulation on portion and a stimulation off portion, wherein a burst of pulses is delivered during the stimulation on portion and no stimulation is delivered during the stimulation off portion, wherein a duty cycle of the stimulation cycles represents a ratio of a duration of the stimulation on portion to a cycle duration; sensing a physiological parameter selected from a group of parameters consisting of;
heart rate, blood pressure and respiration; andadjusting the duty cycle of the stimulation cycles based on the sensed physiological parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method, comprising:
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delivering vagus nerve stimulation in a recurring succession of stimulation cycles, each cycle including a stimulation on portion and a stimulation off portion, wherein a burst of pulses is delivered during the stimulation on portion and no stimulation is delivered during the stimulation off portion, wherein a duty cycle of the stimulation cycles represents a ratio of a duration of the stimulation on portion to a cycle duration; sensing heart rate; implementing a programmed algorithm to determine a target heart rate; and adjusting the duty cycle of the stimulation cycles based on the sensed heart rate and the target heart rate. - View Dependent Claims (10, 11, 12, 13)
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14. A system, comprising:
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a vagus nerve stimulator configured to deliver vagus nerve stimulation in a recurring succession of stimulation cycles, each cycle including a stimulation on portion and a stimulation off portion, wherein a burst of pulses is delivered during the stimulation on portion and no stimulation is delivered during the stimulation off portion, wherein a duty cycle of the stimulation cycles represents a ratio of a duration of the stimulation on portion to a cycle duration; a physiological parameter monitor configured to monitor a physiological parameter selected from a group of parameters consisting of;
heart rate, blood pressure and respiration; anda controller configured to adjust the duty cycle of the stimulation cycles based on the sensed physiological parameter. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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Specification